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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About NEOPRATE INJECTION 5ML

NEOPRATE INJECTION 5ML belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, NEOPRATE INJECTION 5ML is also used to treat bipolar disorder. Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behavior, and loss of awareness. Bipolar disorder is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. 
­ 
NEOPRATE INJECTION 5ML contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. NEOPRATE INJECTION 5ML increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
NEOPRATE INJECTION 5ML will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as sleepiness, dizziness, nausea, headache, and asthenia (weakness). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are of childbearing age, use effective contraception while on treatment with NEOPRATE INJECTION 5ML. Inform your doctor before taking NEOPRATE INJECTION 5ML if you are pregnant or breastfeeding. Do not drive or operate machinery as NEOPRATE INJECTION 5ML may cause sleepiness and dizziness. Avoid consuming alcohol along with NEOPRATE INJECTION 5ML as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of NEOPRATE INJECTION 5ML

Epilepsy/seizures, Bipolar disorder

Directions for Use

NEOPRATE INJECTION 5ML will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

NEOPRATE INJECTION 5ML belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). NEOPRATE INJECTION 5ML decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Additionally, NEOPRATE INJECTION 5ML is also used to treat bipolar disorder. NEOPRATE INJECTION 5ML increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of NEOPRATE INJECTION 5ML

  • Somnolence (sleepiness)
  • Dizziness
  • Nausea
  • Headache
  • Asthenia (weakness)
  • Paresthesia (prickling or burning sensation)

Drug Warnings

Do not take NEOPRATE INJECTION 5ML if you are allergic to any of its contents, if you have urea cycle problems, mitochondrial disorders, or hepatic disease/dysfunction. Inform your doctor if you have/had liver problems, porphyria (blood disorder), diabetes, immune system disorder, bleeding problems, systemic lupus erythematosus (a rare skin condition), or kidney problems. NEOPRATE INJECTION 5ML may cause hepatotoxicity (liver damage); consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). NEOPRATE INJECTION 5ML may also cause pancreatitis (inflammation of the pancreas); consult your doctor if you experience symptoms such as abdominal pain, vomiting, nausea, and/or anorexia (eating disorder).

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateLeflunomide
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Neoprate Injection 5ml:
Combining Sodium phenylbutyrate and Neoprate Injection 5ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Neoprate Injection 5ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Leflunomide and Neoprate Injection 5ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Neoprate Injection 5ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Lithium with Neoprate Injection 5ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Neoprate Injection 5ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Teriflunomide and Neoprate Injection 5ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Vorinostat with Neoprate Injection 5ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Neoprate Injection 5ml:
The combined use of Ertapenem and Neoprate Injection 5ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Neoprate Injection 5ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Neoprate Injection 5ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Meropenam and Neoprate Injection 5ml together can reduce the effect of Neoprate Injection 5ml.

How to manage the interaction:
Co-administration of Meropenam and Neoprate Injection 5ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Neoprate Injection 5ml:
Using buprenorphine together with Neoprate Injection 5ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Neoprate Injection 5ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Neoprate Injection 5ml:
Co-administration of Ketamine and Neoprate Injection 5ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Neoprate Injection 5ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

NEOPRATE INJECTION 5ML Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

NEOPRATE INJECTION 5ML decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizures episodes.

NEOPRATE INJECTION 5ML is used to treat bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

NEOPRATE INJECTION 5ML may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

NEOPRATE INJECTION 5ML may cause hepatotoxicity (liver damage). Consult your doctor if you experience symptoms such as weakness, facial swelling, vomiting, malaise (general discomfort), lethargy (lack of energy or enthusiasm), and anorexia (eating disorder). Serum liver tests before starting NEOPRATE INJECTION 5ML and at regular intervals for at least six months are advised.

NEOPRATE INJECTION 5ML should not be administered to women of child-bearing age unless it is essential to manage her condition. Women of child-bearing age must use effective contraception whilst on treatment with NEOPRATE INJECTION 5ML.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • LAMOTRIGINE
  • FELBAMATE
  • ETHOSUXIMIDE
  • WARFARIN
  • ZIDOVUDINE
  • DIAZEPAM
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • RIFAMPICIN

Special Advise

  • Contact your doctor immediately if you develop suicidal thoughts such as harming or killing yourself.
  • Regular tests such as serum liver tests, platelet count, coagulation tests, and ammonia level tests are advised whilst on treatment with NEOPRATE INJECTION 5ML.
  • If you are of childbearing age, use effective contraception during the entire treatment with NEOPRATE INJECTION 5ML.
  • Consult your doctor immediately if you become pregnant while on treatment with NEOPRATE INJECTION 5ML.

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumour, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. Symptoms of manic episodes include high energy, loss of touch with reality, and reduced need for sleep. Symptoms of depressive episodes include low motivation, low energy, and loss of interest in daily life.

Side effects of Neoprate Injection 5ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
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