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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS

About Neopride Total 20 Capsule 15's

Neopride Total 20 Capsule 15's belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity. 
 
Neopride Total 20 Capsule 15's is a combination of two drugs, namely: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Neopride Total 20 Capsule 15's helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
 
You are advised to take Neopride Total 20 Capsule 15's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Neopride Total 20 Capsule 15's may cause osteoporosis and hypomagnesemia. Consult a doctor if you are pregnant or breastfeeding. Neopride Total 20 Capsule 15's may cause drowsiness and dizziness, so drive only if you are alert. Neopride Total 20 Capsule 15's is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Neopride Total 20 Capsule 15's as it could lead to increased drowsiness and elevate stomach acid production. 

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Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Neopride Total 20 Capsule 15's

Gastro-oesophageal reflux disease, acidity, indigestion heartburn, and peptic ulcers.

Medicinal Benefits

Neopride Total 20 Capsule 15's is a combination of two drugs, namely: Rabeprazole and Levosulpiride. Neopride Total 20 Capsule 15's belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. Rabeprazole is a proton pump inhibitor that works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Neopride Total 20 Capsule 15's helps in preventing acid reflux, thereby providing relief from acidity and heartburn. 

Side Effects of Neopride Total 20 Capsule 15's

  • Headache
  • Nausea
  • Vomiting
  • Flatulence
  • Abdominal pain
  • Dizziness
  • Diarrhoea 

Directions for Use

Take Neopride Total 20 Capsule 15's 1hour prior to food. Swallow Neopride Total 20 Capsule 15's as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Neopride Total 20 Capsule 15's if you are allergic to any of its components. Inform your doctor if you have a history of pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney or liver impairment. Neopride Total 20 Capsule 15's may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment. Consult a doctor if you are pregnant or breastfeeding. Neopride Total 20 Capsule 15's may cause dizziness and drowsiness, so drive only if you are alert. Neopride Total 20 Capsule 15's is not recommended for children as safety and effectiveness have not been established.

Therapeutic Class

ANTACIDS, ANTIULCERANTS

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
How does the drug interact with Neopride Total 20 Capsule 15's:
When used in combination with erlotinib, Neopride Total 20 Capsule 15's may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Neopride Total 20 Capsule 15's with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Neopride Total 20 Capsule 15's:
Co-administration of Neopride Total 20 Capsule 15's can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Neopride Total 20 Capsule 15's with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleDasatinib
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
Taking Neopride Total 20 Capsule 15's together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Neopride Total 20 Capsule 15's and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePazopanib
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
Taking Neopride Total 20 Capsule 15's together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Neopride Total 20 Capsule 15's and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
RabeprazoleClopidogrel
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
Taking Clopidogrel with Neopride Total 20 Capsule 15's can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and Neopride Total 20 Capsule 15's together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
RabeprazoleGefitinib
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
Taking Neopride Total 20 Capsule 15's together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Neopride Total 20 Capsule 15's and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Neopride Total 20 Capsule 15's. Do not discontinue any medications without a doctor's advice.
RabeprazoleDasatinib
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
Taking Dasatinib with Neopride Total 20 Capsule 15's may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Neopride Total 20 Capsule 15's with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
RabeprazolePhenytoin
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
When Phenytoin and Neopride Total 20 Capsule 15's are taken in combination, Phenytoin will reduce the concentration or impact of Neopride Total 20 Capsule 15's.

How to manage the interaction:
Although taking Phenytoin and Neopride Total 20 Capsule 15's together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleMethotrexate
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
Co-administration of Methotrexate with Neopride Total 20 Capsule 15's can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Neopride Total 20 Capsule 15's and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleAcalabrutinib
Severe
How does the drug interact with Neopride Total 20 Capsule 15's:
Taking Neopride Total 20 Capsule 15's together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Neopride Total 20 Capsule 15's and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • METHOTREXATE
  • DIGOXIN
  • MYCOPHENOLATE MOFETIL
  • TACROLIMUS
  • AMOXICILLIN
  • CLARITHROMYCIN

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Special Advise

  • Neopride Total 20 Capsule 15's might cause false-positive results for secretin stimulation test, prolactin test, and tests for tetrahydrocannabinol (THC). Inform the person doing the tests that you are taking Neopride Total 20 Capsule 15's.
  • Regular blood tests for monitoring magnesium levels and bone density tests are advised if you are on long-term treatment with Neopride Total 20 Capsule 15's.
  • Inform your doctor if you are due to have Chromogranin A test.

Author Details

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Disease/Condition Glossary

Acidity: The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn, and peptic ulcers.

Gastroesophageal reflux disease (GERD): It occurs when stomach acid frequently flows into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. 

Stomach ulcers: Stomach ulcers are sores that develop on the stomach and intestine lining due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. 

Indigestion: Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea, and vomiting.

Neopride Total 20 Capsule 15's Substitute

Substitutes safety advice
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