Neotagmin-P Injection 5 ml is an anticholinergic agent/acetylcholinesterase inhibitor combination that is primarily used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants.

Neotagmin-P Injection 5 ml is made of Glycopyrrolate and Neostigmine. Neostigmine raises acetylcholine levels by inhibiting an enzyme that breaks down acetylcholine, which is involved in nerve impulse transmission and muscle action. On the other hand, Glycopyrrolate is an anticholinergic that inhibits the negative effects of Neostigmine, such as slowed heart rate and excessive saliva production.

Neotagmin-P Injection 5 ml is prescription-only medication available in the form of injection. It is administered by a qualified healthcare professional. The common side-effects of Neotagmin-P Injection 5 ml are pain, itching, swelling or redness around the site of injection, constipation, dry mouth, nausea, vomiting, visual disturbance, dizziness, diarrhoea, too much saliva, dryness of skin, increased pressure on the eye, stomach cramps, the uncontrolled need of passing urine. Most of these side effects of Neotagmin-P Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not use Neotagmin-P Injection 5 ml if you are allergic to Glycopyrrolate, Neostigmine Methylsulphate, or other substances in this drug, or if you are receiving Suxamethonium, a muscle relaxant commonly used during surgery. It is also not suggested if you have difficulties passing urine, intestinal blockage, prolonged QT interval (irregular heart rhythm), or heart problems. If you are pregnant or breastfeeding, suspect you are pregnant or plan to have a baby. Consult your doctor before driving or operating machinery since this medication may impair your ability to drive or operate machinery safely. Neotagmin-P Injection 5 ml can be given to children if medically indicated; the child's age and weight determine the dose.

Neotagmin-P Injection 5 ml is an anticholinergic agent/acetylcholinesterase inhibitor combination that is primarily used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants. Neotagmin-P Injection 5 ml is composed of Glycopyrrolate and Neostigmine. Neostigmine boosts acetylcholine levels by blocking an enzyme that degrades acetylcholine, which is involved in nerve impulse transmission and muscle activity. On the other hand, Glycopyrrolate is an anticholinergic that reduces the unfavourable effects of Neostigmine, such as slow heart rate and increased saliva production.

• Constipation
• Dry mouth
• Nausea
• Vomiting
• Visual disturbance
• Dizziness
• Diarrhoea
• Too much saliva
• Dryness of skin
• Increased pressure on the eye
• Stomach cramps
• Uncontrolled need to pass urine

Do not use Neotagmin-P Injection 5 ml if you are allergic to Glycopyrrolate, Neostigmine Methylsulphate, or other substances in this drug, or if you are receiving Suxamethonium, a muscle relaxant commonly used during surgery. It is also not suggested if you have difficulties passing urine, intestinal blockage, prolonged QT interval (irregular heart rhythm), or heart problems. If you are pregnant or breastfeeding, suspect you are pregnant or plan to have a baby. Let the doctor know about your medical history and the ongoing therapies and medications to avoid potential negative effects or interactions. Consult your doctor before driving or operating machinery since this medication may impair your ability to drive or operate machinery safely. Neotagmin-P Injection 5 ml can be given to children if medically indicated; the child's age and weight determine the dose.

Drug-Drug Interactions: Neotagmin-P Injection 5 ml may interact with certain antidepressant medicines (e.g. lithium, amitriptyline, imipramine), certain medicines used for mental illness (e.g. clozapine), certain pain killers (e.g. nefopam), certain antiviral medicines (e.g. amantadine), muscle relaxant (e.g. Suxamethonium), antibiotics (e.g. gentamicin, streptomycin, colistimethate sodium), certain medicines for heart disease (e.g. procainamide, propafenone, quinidine), certain antimalarial medicines (e.g. chloroquine), and a drug used to treat a variety of ailments such as migraines, heart issues, and anxiety (e.g. propranolol).

Drug-Food Interactions: Do not consume alcohol while taking Neotagmin-P Injection 5 ml as it could lead to increased dizziness and weak eyesight.

Drug-Disease Interactions: Neotagmin-P Injection 5 ml may have interactions with diseases conditions, including difficulties passing urine, intestinal blockage, prolonged QT interval (irregular heart rhythm), heart problems, asthma, glaucoma, intestinal disorders, stomach ulcers, high temperature (fever), low or high blood pressure, heart disorders, overactive thyroid gland, myasthenia gravis (severe muscle weakness and fatigue), epilepsy or Parkinsonism, Pyloric stenosis (gastric outlet obstruction), and kidney or liver disorders.

• LITHIUM
• AMITRIPTYLINE
• IMIPRAMINE
• CLOZAPINE
• NEFOPAM
• AMANTADINE
• SUXAMETHONIUM
• GENTAMICIN
• STREPTOMYCIN
• COLISTIMETHATE SODIUM
• PROCAINAMIDE
• PROPAFENONE
• QUINIDINE
• CHLOROQUINE
• PROPRANOLOL

• Maintain proper weight by following a healthy diet.
• Avoid smoking and alcohol consumption.
• Try to avoid stress by practising meditation or yoga.
• Include fruits and vegetables in your diet as they contain antioxidants.
• Limit foods with high cholesterol and saturated fats.
• Cut down on sugar, salt, and processed foods.
• Drink plenty of water.

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