Neotagmin-P Injection 5 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

MRP ₹94.5

(Inclusive of all Taxes)

₹14.2 Cashback (15%)

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Whats That

About Neotagmin-P Injection 5 ml

Neotagmin-P Injection 5 ml is an anticholinergic agent/acetylcholinesterase inhibitor combination that is primarily used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants.

Neotagmin-P Injection 5 ml is made of Glycopyrrolate and Neostigmine. Neostigmine raises acetylcholine levels by inhibiting an enzyme that breaks down acetylcholine, which is involved in nerve impulse transmission and muscle action. On the other hand, Glycopyrrolate is an anticholinergic that inhibits the negative effects of Neostigmine, such as slowed heart rate and excessive saliva production.

Neotagmin-P Injection 5 ml is prescription-only medication available in the form of injection. It is administered by a qualified healthcare professional. The common side-effects of Neotagmin-P Injection 5 ml are pain, itching, swelling or redness around the site of injection, constipation, dry mouth, nausea, vomiting, visual disturbance, dizziness, diarrhoea, too much saliva, dryness of skin, increased pressure on the eye, stomach cramps, the uncontrolled need of passing urine. Most of these side effects of Neotagmin-P Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not use Neotagmin-P Injection 5 ml if you are allergic to Glycopyrrolate, Neostigmine Methylsulphate, or other substances in this drug, or if you are receiving Suxamethonium, a muscle relaxant commonly used during surgery. It is also not suggested if you have difficulties passing urine, intestinal blockage, prolonged QT interval (irregular heart rhythm), or heart problems. If you are pregnant or breastfeeding, suspect you are pregnant or plan to have a baby. Consult your doctor before driving or operating machinery since this medication may impair your ability to drive or operate machinery safely. Neotagmin-P Injection 5 ml can be given to children if medically indicated; the child's age and weight determine the dose.

Uses of Neotagmin-P Injection 5 ml

Used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants.

Directions for Use

Neotagmin-P Injection 5 ml will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Neotagmin-P Injection 5 ml is an anticholinergic agent/acetylcholinesterase inhibitor combination that is primarily used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants. Neotagmin-P Injection 5 ml is composed of Glycopyrrolate and Neostigmine. Neostigmine boosts acetylcholine levels by blocking an enzyme that degrades acetylcholine, which is involved in nerve impulse transmission and muscle activity. On the other hand, Glycopyrrolate is an anticholinergic that reduces the unfavourable effects of Neostigmine, such as slow heart rate and increased saliva production.

Storage

Keep out of sight and reach of children.

Drug Warnings

Do not use Neotagmin-P Injection 5 ml if you are allergic to Glycopyrrolate, Neostigmine Methylsulphate, or other substances in this drug, or if you are receiving Suxamethonium, a muscle relaxant commonly used during surgery. It is also not suggested if you have difficulties passing urine, intestinal blockage, prolonged QT interval (irregular heart rhythm), or heart problems. If you are pregnant or breastfeeding, suspect you are pregnant or plan to have a baby. Let the doctor know about your medical history and the ongoing therapies and medications to avoid potential negative effects or interactions. Consult your doctor before driving or operating machinery since this medication may impair your ability to drive or operate machinery safely. Neotagmin-P Injection 5 ml can be given to children if medically indicated; the child's age and weight determine the dose.

Drug-Drug Interactions

Glycopyrronium bromideLevodopa

Severe

Glycopyrronium bromideDigoxin

Severe

Drug-Drug Interactions

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Glycopyrronium bromideLevodopa

Severe

How does the drug interact with Neotagmin-P Injection 5 ml:
Coadministration of levodopa with Neotagmin-P Injection 5 ml can significantly decrease the blood levels of levodopa.

How to manage the interaction:
Although using Neotagmin-P Injection 5 ml and levodopa together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without a doctor's advice.

Glycopyrronium bromideDigoxin

Severe

How does the drug interact with Neotagmin-P Injection 5 ml:
Co-administration of Digoxin and Neotagmin-P Injection 5 ml may increase the serum concentration of Digoxin and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Digoxin and Neotagmin-P Injection 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Glycopyrronium bromidePotassium chloride

Severe

How does the drug interact with Neotagmin-P Injection 5 ml:
The use of Potassium chloride and Neotagmin-P Injection 5 ml can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Using Potassium chloride and Neotagmin-P Injection 5 ml together can lead to an interaction, however, it can be taken if advised by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Glycopyrronium bromideSecretin

Severe

How does the drug interact with Neotagmin-P Injection 5 ml:
The combined use of secretin and Neotagmin-P Injection 5 ml can inhibit gastric acid secretion.

How to manage the interaction:
Although using secretin and Neotagmin-P Injection 5 ml together can lead to an interaction, it can be taken if advised by your doctor.

Glycopyrronium bromidePramlintide

Severe

How does the drug interact with Neotagmin-P Injection 5 ml:
Taking Pramlintide with Neotagmin-P Injection 5 ml can cause slow stomach emptying or slow the intestinal absorption of nutrients.

How to manage the interaction:
Although using Pramlintide and Neotagmin-P Injection 5 ml together can lead to an interaction, it can be taken if advised by your doctor.

NeostigmineTramadol

Severe

How does the drug interact with Neotagmin-P Injection 5 ml:
Co-administration of tramadol with Neotagmin-P Injection 5 ml can increase the effect of tramadol.

How to manage the interaction:
Taking Neotagmin-P Injection 5 ml with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain proper weight by following a healthy diet.
Avoid smoking and alcohol consumption.
Try to avoid stress by practising meditation or yoga.
Include fruits and vegetables in your diet as they contain antioxidants.
Limit foods with high cholesterol and saturated fats.
Cut down on sugar, salt, and processed foods.
Drink plenty of water.

Side Effects of Neotagmin-P Injection 5 ml

Constipation
Dry mouth
Nausea
Vomiting
Visual disturbance
Dizziness
Diarrhoea
Too much saliva
Dryness of skin
Increased pressure on the eye
Stomach cramps
Uncontrolled need to pass urine

Habit Forming

No

Therapeutic Class

MUSCLE STIMULANTS AND CHOLINESTERASE INHIBITORS

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Neotagmin-P Injection 5 ml work?

Neotagmin-P Injection 5 ml is an anticholinergic agent/acetylcholinesterase inhibitor combination that is primarily used at the end of an operation to reverse the effects of anaesthetics and muscle relaxants. Neotagmin-P Injection 5 ml is composed of Glycopyrrolate and Neostigmine. Neostigmine boosts acetylcholine levels by blocking an enzyme that degrades acetylcholine, which is involved in nerve impulse transmission and muscle activity. On the other hand, Glycopyrrolate is an anticholinergic that reduces the unfavourable effects of Neostigmine, such as slow heart rate and increased saliva production.

In which conditions should I avoid using Neotagmin-P Injection 5 ml?

Do not use Neotagmin-P Injection 5 ml in people with difficulties passing urine, intestinal blockage, prolonged QT interval (irregular heart rhythm), or heart problems. As a precautionary measure, please let your doctor know if you have any other medical problems before starting Neotagmin-P Injection 5 ml.

Can I use Neotagmin-P Injection 5 ml on my own?

Neotagmin-P Injection 5 ml is prescription-only medication available in the form of injection. It is administered by a qualified healthcare professional. Do not self-administer.

Is it necessary for everyone to use Neotagmin-P Injection 5 ml after surgery?

It is not required to utilise Neotagmin-P Injection 5 ml in every patient following surgery. It can only be used to reverse the effects of medications used during surgery based on the patient's medical state following surgery.

How to store and dispose of Neotagmin-P Injection 5 ml?

Keep the Neotagmin-P Injection 5 ml in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.

Drug-Drug Interactions Checker List