apollo
0
Written By Urvashi Bharti , MBBS
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Manufacturer/Marketer

Zenlabs Ethica Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Neufil 300 mcg Injection

Neufil 300 mcg Injection belongs to the class of medicine called 'hematopoietic agent' used to treat neutropenia, a lack of certain white blood cells caused by cancer, bone marrow transplant, receiving chemotherapy, bacterial infections or other conditions. Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the blood is decreased. White blood cells (neutrophils) protect the body from infections. Without enough neutrophils, the body can not fight off bacteria which increases the risk of many types of infections.

Neufil 300 mcg Injection contains ' Filgrastim ' that stimulates the bone marrow (the tissue where new blood cells are made) to produce more white blood cells that help fight infection. Neufil 300 mcg Injection is used to improve white blood cells during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells), neutropenia in patients with HIV infection, and before stem cell donation.

You are advised to take Neufil 300 mcg Injection for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as thrombocytopenia (low platelets level), anaemia (low red blood cell), headache, diarrhoea, vomiting, nausea, alopecia (unusual hair loss), tiredness, soreness, swelling of the digestive tract, fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Neufil 300 mcg Injection for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Neufil 300 mcg Injection if you are pregnant or planning for pregnancy. Neufil 300 mcg Injection should not be taken by breastfeeding mothers unless prescribed. Neufil 300 mcg Injection should be given to children under strict medical supervision. Please tell your doctor before using Neufil 300 mcg Injection if you have sickle cell anaemia, as Neufil 300 mcg Injection may cause sickle cell crisis and osteoporosis (bone disease). Regular blood tests will be taken to monitor the number of white blood cells in the body. Inform your doctor about your health condition and medicines to rule out unpleasant side effects. Neufil 300 mcg Injection is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees celsius else its efficacy might get lost. Do not store in the freezer or the fridge.

Uses of Neufil 300 mcg Injection

Neutropenia (low number of white blood neutropenia cells),  Neutropenia during Chemotherapy,  Neutropenia after Bone marrow transplantation,  Neutropenia in patients with HIV infection,  peripheral blood stem cell mobilisation (to stimulate stem cells to enter the bloodstream to be collected and used in bone marrow transplantation)

Directions for Use

Neufil 300 mcg Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Neufil 300 mcg Injection contains ‘Filgrastim’ is a white blood cell growth factor. It belongs to a group of proteins called cytokines and is very similar to a natural protein (granulocyte-colony stimulating factor) produced by your body. Neufil 300 mcg Injection works by stimulating the bone marrow (the tissue where new blood cells are made) to produce more white blood cells that help fight infection. Neufil 300 mcg Injection is used to improve white blood cells during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells), neutropenia in patients with HIV infection and before stem cell donation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Neufil 300 mcg Injection

  • Thrombocytopenia (low platelets level)
  • Anaemia (low red blood cell)
  • Headache
  • Diarrhoea
  • Vomiting
  • Nausea
  • Alopecia (unusual hair loss)
  • Tiredness
  • Soreness and swelling of the digestive tract
  • Fever

Drug Warnings

Do not take Neufil 300 mcg Injection if you are allergic to Neufil 300 mcg Injection or any of its ingredients it may contain inactive ingredients (such as dry natural rubber/latex in the needle cover on the prefilled syringe), which can cause allergic reactions or other problems. Before starting treatment with Neufil 300 mcg Injection , inform your doctor if you have sickle cell anaemia, osteoporosis (bone disease), kidney disease, liver disease, spleen problems, heart problems, and radiation treatment. Neufil 300 mcg Injection can cause the spleen to become enlarged, and it could rupture (tear). Inform your doctor right away if you have sudden or severe pain in your left upper stomach spreading up to your shoulder. If you receive chemotherapy or bone marrow transplant, do not use Neufil 300 mcg Injection within 24 hours before or 24 hours after you receive chemotherapy or bone marrow transplant.  Do not take Neufil 300 mcg Injection if you are pregnant or breastfeeding unless prescribed by the doctor. Neufil 300 mcg Injection can be given safely to children only when prescribed. Neufil 300 mcg Injection may cause dizziness, so drive only if you are alert. Avoid consuming alcohol along with Neufil 300 mcg Injection as it could lead to increased drowsiness. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements. 

Drug-Drug Interactions

verifiedApollotooltip
FilgrastimMercaptopurine
Severe
FilgrastimBleomycin
Severe

Drug-Drug Interactions

Login/Sign Up

FilgrastimMercaptopurine
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Co-administration of Neufil 300 mcg Injection 0.5 ml together with Mercaptopurine can reduce the effects of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Although taking Neufil 300 mcg Injection 0.5 ml and Mercaptopurine together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
FilgrastimBleomycin
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Combining Neufil 300 mcg Injection 0.5 ml with Bleomycin can increase the risk of developing lung disorders.

How to manage the interaction:
There may be a possibility of interaction between Neufil 300 mcg Injection 0.5 ml and Bleomycin, it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
FilgrastimMelphalan
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Co-administration of Neufil 300 mcg Injection 0.5 ml together with Melphalan can reduce the effect of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Although taking Neufil 300 mcg Injection 0.5 ml and Melphalan together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
FilgrastimMitomycin
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Using Neufil 300 mcg Injection 0.5 ml together with mitomycin reduce the effects of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Co-administration of Neufil 300 mcg Injection 0.5 ml with Mitomycin can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
FilgrastimBusulfan
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Coadministration of Neufil 300 mcg Injection 0.5 ml with Busulfan can reduce the effects of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Although there is a possible interaction between Neufil 300 mcg Injection 0.5 ml and Busulfan, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without talking to your doctor.
FilgrastimImatinib
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Taking Neufil 300 mcg Injection 0.5 ml together with Imatinib can reduce the effect of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
There may be a possibility of interaction between Neufil 300 mcg Injection 0.5 ml and Imatinib, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FilgrastimBrentuximab
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Coadministration of Neufil 300 mcg Injection 0.5 ml with Brentuximab can decrease the therapeutic effect of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Although there is an interaction between Neufil 300 mcg Injection 0.5 ml and brentuximab, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FilgrastimBexarotene
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Coadministration of Neufil 300 mcg Injection 0.5 ml with Bexarotene can alter the effect of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Although there is an interaction between Neufil 300 mcg Injection 0.5 ml and bexarotene, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FilgrastimPentostatin
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Using Neufil 300 mcg Injection 0.5 ml together with pentostatin can reduce the effect of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Although there is a possible interaction between Neufil 300 mcg Injection 0.5 ml and Pentostatin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
FilgrastimLenalidomide
Severe
How does the drug interact with Neufil 300 mcg Injection 0.5 ml:
Using Neufil 300 mcg Injection 0.5 ml together with lenalidomide can reduce the effect of Neufil 300 mcg Injection 0.5 ml.

How to manage the interaction:
Co-administration of Neufil 300 mcg Injection 0.5 ml with Lenalidomide can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat a well-balanced and healthy diet, as it helps you to recover quickly. A dietitian will help you to create a diet plan based on your health condition. 

  • Avoid eating raw or undercooked food. 

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

  • Limit alcohol consumption and quit smoking. 

Habit Forming

No

Therapeutic Class

HEMATOPOIETIC

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

Neufil 300 mcg Injection contains 'Filgrastim' is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

No, Neufil 300 mcg Injection is not recommended to patients with spleen disorder. It may cause your spleen to become enlarged, and it could rupture. If you experience pain in the left upper stomach/abdominal area or left shoulder, contact your doctor immediately.

If you are being treated for severe chronic neutropenia for a longer period, Neufil 300 mcg Injection may cause blood in your urine (haematuria). Your doctor may regularly test your urine if you experience this side effect or if a protein is found in your urine (proteinuria).

Neufil 300 mcg Injection should be used with caution in patients with kidney diseases. Dose adjustments may be necessary. Neufil 300 mcg Injection cause breathlessness (dyspnoea), tachycardia & wheeze, and even death. If you have had a history of asthma, the more possibility of these systemic allergic-like reactions. Please inform your doctor.

Neufil 300 mcg Injection to be taken with caution, especially if you have had heart problems. The dose may have to be adjusted by your doctor. In some cases, Neufil 300 mcg Injection causes inflammation of the aorta (the large blood vessel which transports blood from the heart to the body) symptoms can include fever, abdominal pain, malaise, back pain, and increased inflammatory markers. Tell your doctor if you experience those symptoms. Please inform your doctor before taking Neufil 300 mcg Injection .

Yes, Neufil 300 mcg Injection may interfere with certain lab tests such as bone imaging and blood tests (elevation in lactate dehydrogenase and alkaline phosphate), possibly causing false test results. Make sure your doctor and laboratory staff know you use Neufil 300 mcg Injection .

Drug-Drug Interactions Checker List

  • ALTRETAMINE
  • BUSULFAN
  • CLADRIBINE
  • PROCARBAZINE
  • PEGFILGRASTIM
  • DACARBAZINE
  • GEMTUZUMAB
  • DINUTUXIMAB
  • BEVACIZUMAB
  • ALEMTUZUMAB
  • CARBOPLATIN
  • BENDAMUSTINE

Special Advise

  • Constantly monitors the number of blood cells in your blood, and your bone density level while you are receiving treatment with Neufil 300 mcg Injection .

  • Do not take any kind of immunization or vaccination without your doctor's approval while using Neufil 300 mcg Injection .

Disease/Condition Glossary

Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the blood is decreased. White blood cells (neutrophils) protect the body from infections. Without enough neutrophils, the body can not fight off bacteria which increases the risk of many types of infections. It can be caused by diseases that damage the bone marrow like cancer chemotherapy, HIV or AIDS, infections or deficiencies in vitamins or minerals, such as vitamin B12, folate, or copper, and autoimmune diseases, including Crohn's disease, lupus, and rheumatoid arthritis. Severe chronic neutropenias arise from the failure of the bone marrow to produce adequate numbers of neutrophils that circulate in the blood. It appears that patients with severe chronic neutropenias are at greater risk of developing leukaemia (blood cancer) than are other people.

whatsapp Floating Button

Add to Cart