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Reviewed By Sureshvarma D , MPharma
Non returnable*
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Manufacturer/Marketer :

Genix Lifescience Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nevilast 30EP Tablet

Nevilast 30EP Tablet belongs to the class of medications called ‘antiretroviral agents’ used in the treatment of HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness and sore throat that usually last for days to several weeks.

Nevilast 30EP Tablet is a combination of three medicines: Stavudine, lamivudine and nevirapine. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. Nevilast 30EP Tablet may cause side effects such as headache, insomnia (difficulty in sleeping), nausea, diarrhea, dry mouth, fever, rash, and peripheral neuropathy (tingling and numbness of feet and hands). Inform your doctor if any of these side effects persist or get worse.

It is not recommended to take Nevilast 30EP Tablet if you are allergic to any contents of it. Before taking Nevilast 30EP Tablet , inform your doctor if you have any liver disease, hepatitis B or C (liver infections), a history of mental illness, seriously overweight and have kidney disease. Inform your doctor if you are pregnant or breastfeeding. Nevilast 30EP Tablet should be used with caution in children and elderly patients. Alcohol consumption may increase the risk of side effects. Nevilast 30EP Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Nevilast 30EP Tablet

HIV infection

Directions for Use

Take Nevilast 30EP Tablet with food or after a meal as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Nevilast 30EP Tablet belongs to the group of medicines called antiretroviral therapy (ART). Nevilast 30EP Tablet contains stavudine, lamivudine, and nevirapine. Nevilast 30EP Tablet work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection. It helps in improving the quality of life of a patient with HIV.

Storage

Keep Nevilast 30EP Tablet out of the sight and reach of children.
Side effects of Nevilast 30EP Tablet
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Maintain good oral hygiene.
  • Rinsing with salt water may also help relieve mouth ulcers.
  • Avoid foods that cause inflammation like spicy, salty or sugary foods.
  • Eat soft foods like yoghurt, apple sauce, and mashed potatoes.
  • Drink enough fluids.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.

Drug Warnings

Inform your doctor if you develop persistent diarrhea or vomiting, as it may affect the effectiveness of Nevilast 30EP Tablet . Nevilast 30EP Tablet may cause pancreatitis (inflammation of the pancreas), so inform your doctor if you develop symptoms such as nausea (feeling sick), vomiting or stomach pain. Nevilast 30EP Tablet may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat) and tremors. Nevilast 30EP Tablet may destroy bone leading to symptoms such as joint stiffness or pain. It may also cause muscle pain, tenderness, or weakness. Speak with your doctor about the precautions to follow to avoid infecting other people as one can still pass on HIV while on this medicine, although the risk is somewhat lowered by antiretroviral therapy, it can spread through sexual contact with a person who already has the infection or by transfer of infected blood. Nevilast 30EP Tablet does not cure HIV infection. Nevilast 30EP Tablet can make hormonal contraceptives less effective or less likely to work. So, use other effective methods for contraception, including a barrier form (cervical cap, condom, diaphragm, or contraceptive sponge) to prevent pregnancy as advised by your doctor. Do not breastfeed while taking this medicine. Nevilast 30EP Tablet is not recommended in pregnancy as could harm the unborn baby or cause birth defects. You may need frequent medical tests while on Nevilast 30EP Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nevilast 30EP Tablet:
Co-administration of Nevilast 30EP Tablet with Ranolazine may significantly reduce the blood levels of Ranolazine. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevilast 30EP Tablet with Ranolazine is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Nevilast 30EP Tablet:
When Atazanavir is taken with Nevilast 30EP Tablet, it can reduce the levels and side effects of atazanavir & increase the blood levels and effects of Nevilast 30EP Tablet.

How to manage the interaction:
Taking Nevilast 30EP Tablet with Atazanavir is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LamivudineEmtricitabine
Critical
How does the drug interact with Nevilast 30EP Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Nevilast 30EP Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
NevirapineLomitapide
Severe
How does the drug interact with Nevilast 30EP Tablet:
Coadministration of Nevilast 30EP Tablet and Lomitapide may increase the risk or severity of liver problems.

How to manage the interaction:
Although taking Nevilast 30EP Tablet and Lomitapide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nevilast 30EP Tablet:
Coadministration of Nevilast 30EP Tablet and Teriflunomide can increase the risk and severity of liver problems.

How to manage the interaction:
Although taking Nevilast 30EP Tablet and Teriflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding make sure to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineMipomersen
Severe
How does the drug interact with Nevilast 30EP Tablet:
Coadministration of Nevilast 30EP Tablet and Mipomersen can increase the risk and severity of liver problems.

How to manage the interaction:
Although taking Nevilast 30EP Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, or bleeding make sure to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
NevirapineBrigatinib
Severe
How does the drug interact with Nevilast 30EP Tablet:
When Brigatinib is taken with Nevilast 30EP Tablet may reduce the blood levels of Brigatinib. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevilast 30EP Tablet with Brigatinib together can possibly result in an interaction, but it can be taken if your doctor has advised it.Do not stop using any medications without a doctor's advice.
NevirapineHydrocodone
Severe
How does the drug interact with Nevilast 30EP Tablet:
Co-administration of Nevilast 30EP Tablet with Hydrocodone may reduce the blood levels of Hydrocodone. This can lead to low treatment outcomes.

How to manage the interaction:
Co-administration of Nevilast 30EP Tablet with Hydrocodone can result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like pain, watery eyes, runny nose, sneezing, yawning, sweating, fever, chills, restlessness, irritability, anxiety, depression, big pupils, shaking, fast heartbeat, twitching, loss of appetite, feeling sick, throwing up, diarrhoea, losing weight or taking too much medicine, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nevilast 30EP Tablet:
When Butorphanol is taken with Nevilast 30EP Tablet may reduce the blood levels of Butorphanol. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Nevilast 30EP Tablet and Butorphanol together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience watery eyes, runny nose, sneezing, yawning, excessive sweating, goose bumps, fever, chills, flushing, restlessness, irritability, anxiety, depression, pupil dilation, tremor, rapid heartbeat, body aches, involuntary twitching and kicking, abdominal cramping, loss of appetite, nausea, vomiting, diarrhea, and weight loss call a doctor right away. Do not discontinue any medications without consulting a doctor.
NevirapinePretomanid
Severe
How does the drug interact with Nevilast 30EP Tablet:
When Pretomanid is taken with Nevilast 30EP Tablet may reduce the blood levels of Pretomanid. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Nevilast 30EP Tablet and Pretomanid together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LAMIVUDINE-150MG+NEVIRAPINE-200MG+STAVUDINE-30MGHigh fat foods
Mild

Drug-Food Interactions

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LAMIVUDINE-150MG+NEVIRAPINE-200MG+STAVUDINE-30MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Taking Nevilast 30EP Tablet with high fatty foods can reduce the effectiveness of Nevilast 30EP Tablet Avoid taking high-fat food while taking Nevilast 30EP Tablet, as this can lead to interaction.

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange and red vegetables, and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration. 
  • Wash your hands properly before and after eating.
  • Make sure you sleep at least 8 hours a day.

Side Effects of Nevilast 30EP Tablet

  • Headache
  • Tiredness
  • Insomnia (difficulty in sleeping)
  • Diarrhea
  • Dryness in mouth
  • Fever
  • Peripheral neuropathy (tingling and numbness of feet and hand)

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nevilast 30EP Tablet is a combination of three medicines: Stavudine, lamivudine and nevirapine. These three drugs work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection.

Nevilast 30EP Tablet may cause side-effects such as muscle pain and discomfort, difficulty in sleeping, stomach pains, allergic reactions, feeling sick, vomiting, inflammation of the liver, changes in the shape or location of body fat. Inform your doctor if any of these side-effects persist or get worse.

Nevilast 30EP Tablet may cause lactic acidosis (excess of lactic acid in the blood), a rare but a severe side effect, especially in women who are very obese. However, if you experience stomach pain, vomiting or nausea while taking Nevilast 30EP Tablet , please consult a doctor immediately.

Nevilast 30EP Tablet doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

No, Nevilast 30EP Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

If you miss a dose of Nevilast 30EP Tablet , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Do not stop taking Nevilast 30EP Tablet without talking to your doctor. If you suddenly stop taking Nevilast 30EP Tablet , you may experience confusion, fever, mental state changes or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.

Drug-Drug Interactions Checker List

  • HYDROXYUREA
  • WARFARIN
  • BACTRIM

Special Advise

  • Nevilast 30EP Tablet may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Nevilast 30EP Tablet should be carefully monitored throughout the treatment.
  • You can still infect other people while taking Nevilast 30EP Tablet . So, use necessary precautions to avoid infecting others.
  • Nevilast 30EP Tablet may cause abnormal liver function tests. So, regular monitoring of liver function is necessary while taking this medicine.

Disease/Condition Glossary

HIV infection: HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition and there is no definite cure for it.  However, it can be controlled by treating with antiretroviral agents.

Have a query?

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Alcohol

Caution

Avoid drinking alcohol while on Nevilast 30EP Tablet as it may increase the risk of liver damage.

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Pregnancy

Caution

Nevilast 30EP Tablet should be used with caution in pregnant women. It is given only if clinically needed and when benefits outweigh the risk.

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Breast Feeding

Caution

If Nevilast 30EP Tablet is prescribed during breastfeeding, the doctor may advise you to stop breastfeeding as this medicine can pass into breast milk.

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Driving

Caution

Nevilast 30EP Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Nevilast 30EP Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nevilast 30EP Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Dose adjustment may be necessary for use in children when prescribed by a child specialist.

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