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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Composition :

NEVIRAPINE-200MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Nevimune Tablet

Nevimune Tablet is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Nevimune Tablet is combined with other antiretroviral medicines to treat HIV infection.

Nevimune Tablet contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection.

Nevimune Tablet may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Nevimune Tablet should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

Nevimune Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. Nevimune Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. Before taking this medicine, inform your doctor if you have liver/kidney disease, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If you are pregnant and breastfeeding, let your doctor know before taking Nevimune Tablet . Nevimune Tablet should be used in children only if recommended by the doctor. 

Uses of Nevimune Tablet

Human Immunodeficiency Virus (HIV) Infection.

Directions for Use

Take this medicine as advised by your doctor. It should be taken with or without food. Swallow as a whole with a glass of water. Do not chew, crush, or break the medicine.

Medicinal Benefits

Nevimune Tablet contains Neviparine, which belongs to the class of non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. Nevimune Tablet is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Nevimune Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Maintain good oral hygiene.
  • Rinsing with salt water may also help relieve mouth ulcers.
  • Avoid foods that cause inflammation like spicy, salty or sugary foods.
  • Eat soft foods like yoghurt, apple sauce, and mashed potatoes.
  • Drink enough fluids.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Nevimune Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with moderate to severe hepatic impairment or used as an occupational or non-occupational post-exposure prophylaxis. This medicine should only be prescribed in patients with CD4+ greater than 250 cells/mm3 (females) and 400 cells/mm3 (males). Inform your doctor about your medical history and the medicines you take to prevent possible interactions. Nevimune Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. If the patient develops any signs or symptoms of hepatitis, increased transaminase, rash, or hypersensitivity reactions, Nevimune Tablet should be discontinued immediately. This medicine may cause dizziness; hence, avoid driving or operating machines while taking Nevimune Tablet . Before taking this medicine, inform your doctor if you have liver/kidney diseases, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If pregnant and breastfeeding, inform your doctor before taking Nevimune Tablet . Nevimune Tablet should be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. Nevimune Tablet treats the infection but does not cure or prevent it.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nevimune Tablet:
Co-administration of Nevimune Tablet with Ranolazine may significantly reduce the blood levels of Ranolazine. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nevimune Tablet with Ranolazine is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Nevimune Tablet:
When Atazanavir is taken with Nevimune Tablet, it can reduce the levels and side effects of atazanavir & increase the blood levels and effects of Nevimune Tablet.

How to manage the interaction:
Taking Nevimune Tablet with Atazanavir is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nevimune Tablet:
When Olaparib is taken with Nevimune Tablet may reduce the blood levels of Olaparib. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Nevimune Tablet and Olaparib, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting a doctor.
NevirapineEtravirine
Severe
How does the drug interact with Nevimune Tablet:
when Nevimune Tablet is used in conjunction with etravirine, the effects of etravirine may be reduced.

How to manage the interaction:
Co-administration of Nevimune Tablet with Etravirine can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nevimune Tablet:
Coadministration of Nevimune Tablet with Apremilast may decrease the blood levels of Apremilast, which may make the medication less effective.

How to manage the interaction:
Although there is a possible interaction between Apremilast and Nevimune Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
NevirapinePretomanid
Severe
How does the drug interact with Nevimune Tablet:
When Pretomanid is taken with Nevimune Tablet may reduce the blood levels of Pretomanid. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Nevimune Tablet and Pretomanid together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nevimune Tablet:
Coadministration of Nevimune Tablet with Amiodarone may decrease the effects of amiodarone. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Amiodarone with Nevimune Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineHydrocodone
Severe
How does the drug interact with Nevimune Tablet:
Co-administration of Nevimune Tablet with Hydrocodone may reduce the blood levels of Hydrocodone. This can lead to low treatment outcomes.

How to manage the interaction:
Co-administration of Nevimune Tablet with Hydrocodone can result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like pain, watery eyes, runny nose, sneezing, yawning, sweating, fever, chills, restlessness, irritability, anxiety, depression, big pupils, shaking, fast heartbeat, twitching, loss of appetite, feeling sick, throwing up, diarrhoea, losing weight or taking too much medicine, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nevimune Tablet:
Coadministration of Nevimune Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Nevimune Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nevimune Tablet:
Taking Cariprazine with Nevimune Tablet may reduce the blood levels of cariprazine, which may make the medication less effective.

How to manage the interaction:
Taking Cariprazine with Nevimune Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.  
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nevimune Tablet contains Neviparine, which works by inhibiting the HIV reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

No, completing the entire treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.

Nevimune Tablet doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections. Nevimune Tablet is used in combination with other anti-retroviral medicines.

Drug-Drug Interactions Checker List

  • CYCLOSERINE
  • TACROLIMUS
  • SIROLIMUS
  • AMIODARONE
  • CARBAMAZEPINE
  • CLONAZEPAM
  • RITONAVIR
  • ITRACONAZOLE
  • LOPINAVIR

Special Advise

  • Get an HIV test done at least every three months.
  • Nevimune Tablet may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Nevimune Tablet should be carefully monitored throughout the treatment.
  • Regular liver function and CBC tests while taking Nevimune Tablet are advised.

Disease/Condition Glossary

HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. Nevimune Tablet helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.

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