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  3. Ngmine 250 Injection 1's

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

BIVALIRUDIN-250MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Ngmine 250 Injection

Ngmine 250 Injection belongs to the group of medicines called blood thinners used to prevent the formation of blood clots. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Ngmine 250 Injection is used in combination with aspirin during Percutaneous transluminal coronary angioplasty (PTCA) and Percutaneous coronary intervention (PCI) (angioplasty procedures) in unstable angina patients to reduce the chance of blood clot formation.

Ngmine 250 Injection contains Bivalirudin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or other severe chest pain-related problems.

Ngmine 250 Injection will be administered by your doctor. So, do not self-administer. The dose of the medicine will be decided by your doctor based on your health condition. Ngmine 250 Injection may cause certain side effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme levels. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Ngmine 250 Injection should not be used if you are allergic to it or if you ever had a brain stroke, bleeding in the brain or transient ischemic attack (stroke). Talk to your doctor before receiving Ngmine 250 Injection if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems, have/had a heart problem, kidney disease or using any blood thinner medicine. Pregnant or breastfeeding mothers should inform the doctor before receiving this medicine. Ngmine 250 Injection is not recommended for children as efficacy and safety have not been established.

Uses of Ngmine 250 Injection

Myocardial infarction (heart attack)

Directions for Use

A trained healthcare professional will administer Ngmine 250 Injection. Hence do not self-administer.

Key Benefits

Ngmine 250 Injection belongs to the group of medicines called antithrombolytic agents (direct thrombin inhibitors) used to prevent the formation of blood clots. Ngmine 250 Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke, especially in people who have had heart surgery, known as angioplasty.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not receive Ngmine 250 Injection if you are allergic to it or if you have a medical condition that causes bleeding from the stomach or intestine, had a transient ischemic attack (stroke) or if you are suffering from severe liver disease. Let your doctor know if you have bleeding problems, had/have a recent serious injury or surgery, kidney/liver disease, or taking any blood thinner medicine before receiving this medicine. Consult your doctor immediately if you develop a medical condition called thrombotic thrombocytopenic purpura (blood disorder) while on treatment with Ngmine 250 Injection. Pregnant or breastfeeding mothers should inform their doctor before receiving this medicine. Ngmine 250 Injection is not recommended for children as efficacy and safety have not been established.

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Side Effects of Ngmine 250 Injection

  • Nose bleeds
  • Skin rash
  • Bleeding in bowels
  • Blood in urine
  • Low haemoglobin
  • Bruising
  • Thrombocytopenia

Habit Forming

No

Therapeutic Class

[ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS]

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FAQs

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • CELECOXIB
  • TRAMADOL
  • CLOPIDOGREL
  • ENOXAPARIN
  • PRASUGREL
  • TICAGRELOR

Special Advise

 Regular blood tests are advised while taking Ngmine 250 Injection to monitor prothrombin, platelets and coagulation time.

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot, preventing bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow which could lead to unstable angina (chest pain).

Heart attack: It is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

Have a query?

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Alcohol

Safe if prescribed

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while receiving Ngmine 250 Injection to prevent unpleasant side effects.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Ngmine 250 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data are available on the effect of Ngmine 250 Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Ngmine 250 Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Safe if prescribed

Ngmine 250 Injection does not affect your ability to drive.

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Liver

Consult your doctor

Ngmine 250 Injection should be used with caution in patients with liver impairment. Please inform your doctor if you have liver disease or any concerns regarding this.

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Kidney

Consult your doctor

Ngmine 250 Injection should be used with caution in patients with kidney impairment. Please inform your doctor if you have kidney disease or any concerns regarding this.

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Children

Safe if prescribed

Ngmine 250 Injection is not recommended for use in children, as efficacy and safety have not been established.

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