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Whats That
About Nicoduce 48mg Injection
Nicoduce 48mg Injection belongs to a class of medication called 'vasodilators' used to prevent or treat angina pectoris (heart-related chest pain) in adults who cannot take beta-blockers (blood pressure-lowering pills). Angina pectoris is a kind of chest pain due to decreased blood flow to the heart. It is a symptom of coronary artery disease.
Nicoduce 48mg Injection contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels. Thereby, Nicoduce 48mg Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicoduce 48mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.
Nicoduce 48mg Injection will be administered by a healthcare professional; do not self-administer. Some people may experience headache, nausea, vomiting, dizziness, weakness or flushing (reddening of the skin). Most of these side effects of Nicoduce 48mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Nicorandil or any other medicines, inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Nicoduce 48mg Injection. Drive only if you are alert as Nicoduce 48mg Injection may cause dizziness or weakness. Avoid alcohol consumption with Nicoduce 48mg Injection as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Nicoduce 48mg Injection as it may affect blood pressure.
Uses of Nicoduce 48mg Injection
Directions for Use
Key Benefits
Nicoduce 48mg Injection contains Nicorandil, a potassium-channel activator used to prevent or treat angina pectoris (chest pain). Nicoduce 48mg Injection works by opening potassium channels present on the muscle cells within the blood vessels' walls and relaxing these muscle cells and widening blood vessels. Thereby, Nicoduce 48mg Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicoduce 48mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart. Nicoduce 48mg Injection is given to adults who cannot tolerate other heart medicines such as calcium antagonists or beta-blockers.
Storage
Drug Warnings
If you are allergic to Nicorandil or any other medicines, please tell your doctor. Avoid taking Nicoduce 48mg Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems. If you are pregnant or breastfeeding, please consult a doctor. Nicoduce 48mg Injection is not recommended for children as safety and effectiveness were not established. Drive only if you are alert as Nicoduce 48mg Injection may cause dizziness or weakness. Avoid alcohol consumption with Nicoduce 48mg Injection as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Nicoduce 48mg Injection as it may affect blood pressure. If you notice in blood in stools while taking Nicoduce 48mg Injection, inform your doctor immediately as it may be due to ulcers in the stomach, intestines or back passage.
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Side Effects of Nicoduce 48mg Injection
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Disease/Condition Glossary
Angina pectoris: Angina pectoris is a type of chest pain caused by decreased blood flow to the heart, resulting in inadequate oxygen supply to the heart muscle. Emotional stress or physical activity are common causes of chest pain. Angina is a sign that you have coronary artery disease. Angina symptoms include dizziness, shortness of breath, nausea, fatigue, anxiety, or excessive sweating. Smoking, diabetes, being overweight, high blood pressure, high cholesterol, not exercising, or a family history of heart disease are all risk factors for angina.

Have a query?
Alcohol
Safe if prescribed
You are recommended to avoid consumption of alcohol with Nicoduce 48mg Injection as it may cause severely low blood pressure.
Pregnancy
Consult your doctor
There is limited information on the use of Nicoduce 48mg Injection in pregnant women. Usually, it is not recommended for pregnant women. Therefore, if you are pregnant or planning pregnancy, please inform your doctor.
Breast Feeding
Consult your doctor
There is limited information on the use of Nicoduce 48mg Injection in breastfeeding mothers. Therefore, please inform your doctor if you are a breastfeeding mother.
Driving
Safe if prescribed
Nicoduce 48mg Injection may cause dizziness or weakness in some people. Therefore, avoid driving if you feel dizzy or weak after taking Nicoduce 48mg Injection.
Liver
Consult your doctor
Take Nicoduce 48mg Injection with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Consult your doctor
Take Nicoduce 48mg Injection with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
Safe if prescribed
Nicoduce 48mg Injection is not recommended for children as safety and effectiveness were not established. However, please consult a doctor if you have any concerns regarding this.