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About Nifetolol 50 mg/20 mg Tablet

Nifetolol 50 mg/20 mg Tablet belongs to the class of combination medication called 'anti-hypertensive drugs,' primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against blood vessels' walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack, and kidney failure.

Nifetolol 50 mg/20 mg Tablet contains Atenolol (beta-blocker) and Nifedipine (calcium channel blocker). Atenolol works by reducing the heart rate and makes the heart pump blood efficiently throughout the body. Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results.

Take Nifetolol 50 mg/20 mg Tablet as prescribed by your doctor. You are advised to take Nifetolol 50 mg/20 mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience blurred vision, sweating, tiredness, dehydration, constipation, dizziness, headache, nausea, cold hands or feet, and muscle cramps. Most of these side effects of Nifetolol 50 mg/20 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking Nifetolol 50 mg/20 mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Inform your doctor if you are suffering from kidney, liver, heart diseases, diabetes, gout, and asthma. Please tell your doctor if you are taking any other medicines or have any allergic reactions to Nifetolol 50 mg/20 mg Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Do not eat grapefruit or drink grapefruit juice while you're taking Nifetolol 50 mg/20 mg Tablet . It can make side effects worse.  If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Nifetolol 50 mg/20 mg Tablet can be prescribed accordingly.

Uses of Nifetolol 50 mg/20 mg Tablet

Hypertension (high blood pressure)

Directions for Use

Take Nifetolol 50 mg/20 mg Tablet with or without food or as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Nifetolol 50 mg/20 mg Tablet treats hypertension (high blood pressure), consisting of Atenolol (beta-blocker) and Nifedipine (calcium channel blocker). Atenolol works by blocking the release of stress hormones (like adrenaline or non-adrenaline), thereby relieving angina (chest pain) and uneven heartbeats (arrhythmias).  Atenolol also protects the heart during the treatment of a heart attack.  Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective and also for the best results. Thus, Nifetolol 50 mg/20 mg Tablet reduces raised blood pressure by minimizing fluid overload (oedema) and reducing the heart's blood-pumping activity.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Nifetolol 50 mg/20 mg Tablet if you are allergic to Nifetolol 50 mg/20 mg Tablet or any of its components. Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overactive thyroid gland), liver problems, and adrenal gland diseases. Let your doctor know if you have anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders, and asthma before starting Nifetolol 50 mg/20 mg Tablet . It is essential to let your doctor know if you are a breastfeeding mother before using Nifetolol 50 mg/20 mg Tablet since Indapamide may pass into the breast milk. Please ask your doctor if you plan to conceive or are pregnant before using Nifetolol 50 mg/20 mg Tablet . Nifetolol 50 mg/20 mg Tablet can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness. Nifetolol 50 mg/20 mg Tablet is not recommended in people less than 18 years of age.

Drug-Drug Interactions

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NifedipineCarbamazepine
Critical
AtenololSaquinavir
Severe

Drug-Drug Interactions

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NifedipineCarbamazepine
Critical
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Coadministration of Nifetolol 50 mg/20 mg Tablet with Carbamazepine can reduce the blood levels of Nifetolol 50 mg/20 mg Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet with Carbamazepine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AtenololSaquinavir
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Coadministration of Nifetolol 50 mg/20 mg Tablet with saquinavir increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet and saquinavir together can result in an interaction, it can be taken if a doctor has advised it. However, if you happen to experience sudden dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat, you should seek immediate medical attention. Do not discontinue the use of any medication without a doctor's advice.
AtenololRitodrine
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Coadministration of Nifetolol 50 mg/20 mg Tablet and ritodrine may cause either medication to be less effective.

How to manage the interaction:
Although taking Nifetolol 50 mg/20 mg Tablet with ritodrine can result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
AtenololAcebutolol
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Coadministration of Nifetolol 50 mg/20 mg Tablet and Acebutolol they both may enhance blood pressure-lowering effect.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet and acebutolol together can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AtenololTizanidine
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Coadministration of Tizanidine and Nifetolol 50 mg/20 mg Tablet can increase the risk or severity of side effects like low blood pressure.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet and tizanidine together may result in an interaction, it can be taken if your doctor has recommended it. However, if you experience headache, dizziness, lightheadedness, sweating, or palpitations, consult the doctor. Do not discontinue any medications without consulting a doctor.
AtenololDiltiazem
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Taking Nifetolol 50 mg/20 mg Tablet and diltiazem together may lead to increased side effects.

How to manage the interaction:
Taking Nifetolol 50 mg/20 mg Tablet and diltiazem together can result in an interaction, it can be taken if a doctor has recommended it. However, if you experience tiredness, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest discomfort, increased or reduced heartbeat, or irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting doctor.
AtenololDolasetron
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Using dolasetron together with Nifetolol 50 mg/20 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Nifetolol 50 mg/20 mg Tablet and Dolasetron, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
AtenololPropranolol
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
Taking Nifetolol 50 mg/20 mg Tablet and propranolol together may lower your blood pressure excessively which may lead to side effects.

How to manage the interaction:
Combined use of Nifetolol 50 mg/20 mg Tablet and propranolol may result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
AtenololDisopyramide
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
When disopyramide is used with Nifetolol 50 mg/20 mg Tablet, it may increase the effects of disopyramide.

How to manage the interaction:
When Nifetolol 50 mg/20 mg Tablet is used with disopyramide, it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, fainting, heart palpitations, slow or fast pulse, or irregular heartbeats, consult the doctor immediately. Do not stop using any medication without consulting a doctor.
AtenololBisoprolol
Severe
How does the drug interact with Nifetolol 50 mg/20 mg Tablet:
When Bisoprolol is combined with Nifetolol 50 mg/20 mg Tablet the severity or risk of side effects may be increased.

How to manage the interaction:
Although there may be an interaction, Nifetolol 50 mg/20 mg Tablet can be taken with bisoprolol if prescribed by the doctor. Consult the prescriber if you experience any unusual side effects. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) between 19.5 and 24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, use only one serving for women and two servings for men.
  • Quit smoking to lower the risk of heart diseases. 
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.
  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.
  • Try including heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil that help in lowering your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nifetolol 50 mg/20 mg Tablet consists of Atenolol and Nifedipine medicines. Atenolol is a 'beta-blocker and treats high blood pressure, angina (chest pain), and uneven heartbeats (arrhythmias) by reducing the heart rate and making the heart pump blood throughout the body. Nifedipine works by relaxing the blood vessels; this lowers your blood pressure and reduces your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

It is advised to consult your doctor before taking Nifetolol 50 mg/20 mg Tablet if you have a history of severe kidney or liver diseases, low potassium levels (hypokalaemia), diabetes, gout, abnormal heart rhythms, thyroid disorders and asthma.

Yes, Nifetolol 50 mg/20 mg Tablet contains nifedipine, which can cause a sudden drop in blood pressure, especially when you start taking Nifetolol 50 mg/20 mg Tablet , to avoid a sudden drop, please get up gently when sitting down to avoid dizziness.

Even though your blood pressure becomes normal after using Nifetolol 50 mg/20 mg Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

If you forget to take Nifetolol 50 mg/20 mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PHENYTOIN
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CHLORTHALIDONE
  • RAMIPRIL
  • METOPROLOL
  • LISINOPRIL
  • AMLODIPINE
  • ALPRAZOLAM
  • RISPERIDONE
  • AMISULPRIDE
  • PIMOZIDE
  • NELFINAVIR
  • RITONAVIR
  • SAQUINAVIR
  • AMPRENAVIR
  • PHENOBARBITAL

Special Advise

  • Monitor your blood pressure regularly and seek medical advice if you notice any drastic fluctuations.
  • Let your anesthetist or medical staff know that you are taking Nifetolol 50 mg/20 mg Tablet since Atenolol can lower blood pressure levels when certain anesthetic medications are given during any operation or surgery.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. Blood pressure is defined as the amount of blood pumped by the heart and the amount of resistance exerted by the arteries against the blood flow. If the heart pumps more blood, then arteries become narrower, and in turn, blood pressure becomes high. If blood pressure becomes uncontrolled, it may lead to serious heart diseases, including stroke and heart attack. Additionally, high blood pressure can also cause brain damage (stroke) and kidney failure. Blood pressure is expressed as systolic and diastolic pressures. Systolic blood pressure represents the contraction and relaxation of the heart. Diastolic pressure is exerted in the blood vessels when the heart beats and is in the resting state. Ideal blood pressure should be between 90/60mmHg and 120/80mmHg. Hypertension is detected when systolic blood pressure is more than 140mmHg, and diastolic pressure is higher than 90mmHg. Some of the symptoms of hypertension include headache, nose bleed, vomiting, and chest pain.

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