NILDEP 25MG TABLET belongs to a group of medicines called 'tricyclic antidepressants' used to treat depression, neuropathic pain, chronic tension-type headache, and migraine in adults. Additionally, NILDEP 25MG TABLET is also used to treat bedwetting at night in children aged 6 years and above. Depression is a mood disorder that affects a person's daily life described as feelings of sadness, loss, or anger. 

NILDEP 25MG TABLET contains Amitriptyline that works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain which communicate between brain cells, thereby helping in the regulation of mood and preventing depression. Besides this, NILDEP 25MG TABLET also the transmission of pain signals, thereby provides relief from neuropathic pain.

You are advised to take NILDEP 25MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as sleepiness, drowsiness, headache, irregular heartbeat, dry mouth, constipation, nausea, weight gain, slurred or slow speech, and congested nose. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking NILDEP 25MG TABLET for as long as your doctor has prescribed. Do not take NILDEP 25MG TABLET if you are pregnant or breastfeeding unless prescribed by the doctor. NILDEP 25MG TABLET causes drowsiness, sleepiness and dizziness, do not drive unless you are alert. NILDEP 25MG TABLET can be given to children over 6years if prescribed by the doctor for bedwetting. NILDEP 25MG TABLET should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with NILDEP 25MG TABLET as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

NILDEP 25MG TABLET belongs to a group of medicines called tricyclic antidepressants. NILDEP 25MG TABLET is used to treat depression, neuropathic pain, chronic tension-type headache, and migraine in adults. NILDEP 25MG TABLET is also used to treat bedwetting at night in children aged 6 years and above. NILDEP 25MG TABLET works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain which communicate between brain cells, thereby helps in regulating mood and treats depression. NILDEP 25MG TABLET prevents the transmission of pain signals, thereby provides relief from neuropathic pain.

• Sleepiness
• Drowsiness
• Headache
• Irregular heartbeat
• Dry mouth
• Constipation
• Nausea
• Weight gain
• Slurred or slow speech
• Congested nose

Do not take NILDEP 25MG TABLET if you are allergic to any of its contents if you recently had a heart attack, or heart problems, are taking other antidepressants like isocarboxazid, phenelzine, selegiline, tranylcypromine or have taken them in the last 14 days, have severe liver disease or if you have taken moclobemide (used to treat depression and social anxiety). Inform your doctor before taking NILDEP 25MG TABLET if you have heart rhythm problems or hypotension. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Do not take NILDEP 25MG TABLET if you are pregnant or breastfeeding unless prescribed. NILDEP 25MG TABLET causes drowsiness and dizziness, do not drive unless you are alert. NILDEP 25MG TABLET can be given to children above 6 years if prescribed by the doctor for treating bedwetting. NILDEP 25MG TABLET should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with NILDEP 25MG TABLET as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as NILDEP 25MG TABLET causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Drug-Drug Interactions: NILDEP 25MG TABLET may have interaction with pain killers (tramadol, trazodone, hydrocodone, oxycodone, acetaminophen), an antidepressant (bupropion, duloxetine, fluoxetine, sertraline), antihistamine (diphenhydramine, cetirizine), sedatives (zolpidem), muscle relaxant (cyclobenzaprine), anti-convulsant (gabapentin, lamotrigine, escitalopram, pregabalin, topiramate), anti-thyroid (levothyroxine), and anti-anxiety (alprazolam).

Drug-Food Interactions: Avoid consuming alcohol along with NILDEP 25MG TABLET as it may increase the sedative effects.

Drug-Disease Interactions: NILDEP 25MG TABLET may have interactions with disease conditions such as heart problems, anticholinergic effects, depression, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, pheochromocytoma, neutropenia, kidney and liver problems.

• TRAMADOL
• TRAZODONE
• HYDROCODONE
• OXYCODONE
• ACETAMINOPHEN
• BUPROPION
• DULOXETINE
• FLUOXETINE
• SERTRALINE
• DIPHENHYDRAMINE
• CETIRIZINE
• ZOLPIDEM
• CYCLOBENZAPRINE
• GABAPENTIN
• LAMOTRIGINE
• ESCITALOPRAM
• PREGABALIN
• TOPIRAMATE
• LEVOTHYROXINE SODIUM
• ALPRAZOLAM

• Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
• Regularly attend therapy sessions.
• Perform meditation and yoga. This helps in relieving stress and provides relaxation.
• Follow a regular sleep pattern to improve the amount and quality of sleep you get.
• Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
• Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters. 
• Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
• Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
• Avoid smoking and alcohol consumption.
• Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drugs use, and medical conditions.