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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About NILDEP 50MG TABLET

NILDEP 50MG TABLET belongs to a group of medicines called 'tricyclic antidepressants' used to treat depression, neuropathic pain, chronic tension-type headache, and migraine in adults. Additionally, NILDEP 50MG TABLET is also used to treat bedwetting at night in children aged 6 years and above. Depression is a mood disorder that affects a person's daily life described as feelings of sadness, loss, or anger. 

NILDEP 50MG TABLET contains Amitriptyline that works by affecting certain chemical messengers (serotonin, norepinephrine) in the brain which communicate between brain cells, thereby helping in the regulation of mood and preventing depression. Besides this, NILDEP 50MG TABLET also the transmission of pain signals, thereby provides relief from neuropathic pain.

You are advised to take NILDEP 50MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as sleepiness, drowsiness, headache, irregular heartbeat, dry mouth, constipation, nausea, weight gain, slurred or slow speech, and congested nose. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking NILDEP 50MG TABLET for as long as your doctor has prescribed. Do not take NILDEP 50MG TABLET if you are pregnant or breastfeeding unless prescribed by the doctor. NILDEP 50MG TABLET causes drowsiness, sleepiness and dizziness, do not drive unless you are alert. NILDEP 50MG TABLET can be given to children over 6years if prescribed by the doctor for bedwetting. NILDEP 50MG TABLET should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with NILDEP 50MG TABLET as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

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Whats That

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of NILDEP 50MG TABLET

Depression

Medicinal Benefits

NILDEP 50MG TABLET belongs to a group of medicines called tricyclic antidepressants. NILDEP 50MG TABLET is used to treat depression, neuropathic pain, chronic tension-type headache, and migraine in adults. NILDEP 50MG TABLET is also used to treat bedwetting at night in children aged 6 years and above. NILDEP 50MG TABLET works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain which communicate between brain cells, thereby helps in regulating mood and treats depression. NILDEP 50MG TABLET prevents the transmission of pain signals, thereby provides relief from neuropathic pain.

Side Effects of NILDEP 50MG TABLET

  • Sleepiness
  • Drowsiness
  • Headache
  • Irregular heartbeat
  • Dry mouth
  • Constipation
  • Nausea
  • Weight gain
  • Slurred or slow speech
  • Congested nose

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take NILDEP 50MG TABLET if you are allergic to any of its contents if you recently had a heart attack, or heart problems, are taking other antidepressants like isocarboxazid, phenelzine, selegiline, tranylcypromine or have taken them in the last 14 days, have severe liver disease or if you have taken moclobemide (used to treat depression and social anxiety). Inform your doctor before taking NILDEP 50MG TABLET if you have heart rhythm problems or hypotension. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Do not take NILDEP 50MG TABLET if you are pregnant or breastfeeding unless prescribed. NILDEP 50MG TABLET causes drowsiness and dizziness, do not drive unless you are alert. NILDEP 50MG TABLET can be given to children above 6 years if prescribed by the doctor for treating bedwetting. NILDEP 50MG TABLET should not be given to children for treating depression or neuropathic pain. Avoid consuming alcohol along with NILDEP 50MG TABLET as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as NILDEP 50MG TABLET causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing).

Therapeutic Class

PSYCHOTHERAPEUTICS

Drug-Drug Interactions

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ImipramineDronedarone
Critical
ImipramineLinezolid
Critical

Drug-Drug Interactions

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ImipramineDronedarone
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Taking Nildep 50 mg Tablet 10's with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Nildep 50 mg Tablet 10's with Dronedarone together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineLinezolid
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Coadministration of Linezolid with Nildep 50 mg Tablet 10's might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Linezolid and Nildep 50 mg Tablet 10's together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineSelegiline
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Co-administration of Nildep 50 mg Tablet 10's with Selegiline might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Nildep 50 mg Tablet 10's and Selegiline together is not recommended as it can result in an interaction. It can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipraminePhenelzine
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Coadministration of Nildep 50 mg Tablet 10's with Phenelzine might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Nildep 50 mg Tablet 10's and Phenelzine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineSafinamide
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Coadministration of Safinamide with Nildep 50 mg Tablet 10's can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking safinamide and Nildep 50 mg Tablet 10's together is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
ImipramineZiprasidone
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Using ziprasidone together with Nildep 50 mg Tablet 10's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Nildep 50 mg Tablet 10's is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
ImipraminePotassium citrate
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Taking Nildep 50 mg Tablet 10's and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Potassium citrate and Nildep 50 mg Tablet 10's is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ImipramineThioridazine
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
When Thioridazine and Nildep 50 mg Tablet 10's are taken together, the body's ability to break down Thioridazine may be reduced. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Nildep 50 mg Tablet 10's with Thioridazine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience extreme drowsiness, confusion, agitation, vomiting, blurred vision, feeling hot or cold, sweating, muscle stiffness, fainting, or seizure, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineSparfloxacin
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Taking Sparfloxacin with Nildep 50 mg Tablet 10's can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sparfloxacin and Nildep 50 mg Tablet 10's together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineTranylcypromine
Critical
How does the drug interact with Nildep 50 mg Tablet 10's:
Taking Tranylcypromine can increase the risk of Nildep 50 mg Tablet 10's on serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Nildep 50 mg Tablet 10's is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TRAMADOL
  • TRAZODONE
  • HYDROCODONE
  • OXYCODONE
  • ACETAMINOPHEN
  • BUPROPION
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • ZOLPIDEM
  • CYCLOBENZAPRINE
  • GABAPENTIN
  • LAMOTRIGINE
  • ESCITALOPRAM
  • PREGABALIN
  • TOPIRAMATE
  • LEVOTHYROXINE SODIUM
  • ALPRAZOLAM

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drugs use, and medical conditions.

NILDEP 50MG TABLET Substitute

Substitutes safety advice
  • Tryptomer 50mg Tablet 15's

    by AYUR

    6.00per tablet
  • Amicon-50mg Tablet 10's

    5.99per tablet
  • Amitryn SR 50 mg Tablet 10's

    20.88per tablet
  • AMITOP SR TABLET

    5.90per tablet
  • VIVAX 50MG TABLET

    5.99per tablet
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