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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Consume Type :

ORAL

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Not Returnable

About Nimech 100mg/500mg Tablet MR

Nimech 100mg/500mg Tablet MR belongs to the group of medicines called muscle relaxants indicated for the relief of painful skeletal muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasms are the involuntary contractions of muscles which can be painful. Musculoskeletal pain affects the bones, muscles, ligaments, tendons and nerves.

Nimech 100mg/500mg Tablet MR is a combination of two drugs: Nimesulide (NSAID) and Chlorzoxazone (Muscle relaxant). Nimesulide works by inhibiting the synthesis of prostaglandins which are responsible for pain and inflammation. Chlorzoxazone acts on the brain and spinal cord centres where it inhibits multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms or stiffness. Together, Nimech 100mg/500mg Tablet MR helps in relieving musculoskeletal pain.

You are advised to take Nimech 100mg/500mg Tablet MR for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Nimech 100mg/500mg Tablet MR may cause common side-effects such as nausea, vomiting, diarrhoea, weakness, and stomach upset. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Nimech 100mg/500mg Tablet MR is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Nimech 100mg/500mg Tablet MR as it could increase the risk of stomach bleeding. Nimech 100mg/500mg Tablet MR may cause sleepiness and dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Nimech 100mg/500mg Tablet MR

Musculoskeletal pain

Directions for Use

Take Nimech 100mg/500mg Tablet MR with food to prevent stomach upset. Swallow Nimech 100mg/500mg Tablet MR as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

Nimech 100mg/500mg Tablet MR is a combination of two drugs, namely: Nimesulide and Chlorzoxazone. Nimech 100mg/500mg Tablet MR is used to relieve pain and stiffness caused by muscle strains and sprains. Nimesulide is an NSAID that inhibits the synthesis of prostaglandins responsible for pain and inflammation. Chlorzoxazone is a muscle relaxant that acts on the brain and spinal cord centres, where it inhibits the multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms or stiffness. Together, Nimech 100mg/500mg Tablet MR helps in relieving pain due to muscle spasms.

Storage

Keep Nimech 100mg/500mg Tablet MR out of reach and sight of children.

Drug Warnings

Do not take Nimech 100mg/500mg Tablet MR if you are allergic to any of its contents, if you have bronchospasm, asthma or breathing problems, gastrointestinal bleeding or perforation, coagulation or bleeding problems and severe heart problems. Inform your doctor if you have heart, kidney or liver impairment. Consult your doctor if you are pregnant or breastfeeding. Nimech 100mg/500mg Tablet MR is not recommended for children as safety has not been established. Avoid consuming alcohol with Nimech 100mg/500mg Tablet MR as it could increase the risk of stomach bleeding. Nimech 100mg/500mg Tablet MR may cause sleepiness and dizziness, so drive only if you are alert. Stop taking Nimech 100mg/500mg Tablet MR and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Nimech 100mg/500mg Tablet MR unless prescribed.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS

Nimech 100mg/500mg Tablet MR Substitute

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FAQs

Nimech 100mg/500mg Tablet MR contains Nimesulide and Chlorzoxazone. Nimesulide works by inhibiting the synthesis of prostaglandins responsible for pain and inflammation. Chlorzoxazone acts on the brain and spinal cord centres, where it inhibits the multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms. Together, Nimech 100mg/500mg Tablet MR helps in relieving musculoskeletal pain.

Nimech 100mg/500mg Tablet MR is generally prescribed for short-term use. Avoid taking Nimech 100mg/500mg Tablet MR for longer durations unless prescribed by the doctor, as it could lead to unpleasant side effects and liver damage. Use the minimum effective dose for the shortest duration of time.

Do not take Nimech 100mg/500mg Tablet MR along with other painkiller medicines unless prescribed by the doctor, as it can lead to unpleasant side effects and can increase the risk of stomach bleeding associated with NSAIDs.

Physical therapy helps relieve muscle spasms. Therefore, proper rest and physical therapy are recommended to enhance and complement treatment with Nimech 100mg/500mg Tablet MR.

Diarrhoea might be a side-effect of Nimech 100mg/500mg Tablet MR. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

Nimech 100mg/500mg Tablet MR contains Nimesulide, an NSAID, which can enhance the activity of anticoagulant drugs leading to an increased risk of bleeding complications. Therefore, it is not recommended to take anti-coagulants along with Nimech 100mg/500mg Tablet MR unless told by the doctor.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ZOLPIDEM
  • DULOXETINE
  • ESCITALOPRAM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • PREGABALIN
  • TOPIRAMATE
  • METOPROLOL
  • HYDROCODONE
  • ACETAMINOPHEN
  • ALPRAZOLAM
  • LITHIUM
  • FUROSEMIDE

Special Advise

  • Nimech 100mg/500mg Tablet MR may rarely cause your urine to turn orange or reddish-purple. This effect is harmless and will disappear when the medication is stopped.
  • If you experience bloody or tarry stools, stop using Nimech 100mg/500mg Tablet MR and consult a doctor.

Disease/Condition Glossary

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons and nerves. It can be acute or chronic and can be localised or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, and cracking or popping sound at the joints.

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