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  1. Home
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  3. NISE D SPRAY 50GM

NISE D SPRAY 50GM, Pack of 1 SPRAY
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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Whats That

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Composition :

DICLOFENAC-1% W/V + LINSEED-3% W/V + MENTHOL-5% W/V + METHYL SALICYLATE-10% W/V

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About NISE D SPRAY

NISE D SPRAY is a topical analgesic (pain killer) primarily used to relieve acute musculoskeletal pain and pain of osteoarthritis of joints. It reduces pain, swelling, and joint stiffness, thereby improving your ability to move and flex the joint.

NISE D SPRAY contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as an anti-inflammatory), and Menthol (as a cooling agent). NISE D SPRAY works by first cooling the skin and then warming it up, which interferes with the pain signal transmission through nerves. Together NISE D SPRAY works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

NISE D SPRAY should only be used if advised by your doctor. NISE D SPRAY should be used for skin only, and accidentally if it gets into your eye, mouth, or nose, rinse with water. NISE D SPRAY should be applied to the affected area with a piece of clean cotton wool or gauze swab. NISE D SPRAY should not be applied more than the recommended dose to avoid unpleasant side effects. Some common side effects of NISE D SPRAY are burning, itching, redness, stinging, and dryness on your skin in the place where NISE D SPRAY is applied. These side effects are usually mild and short-lived. However, if the side effects are persistent, reach out to your doctor.

NISE D SPRAY is contraindicated in children below two years of age. Besides this, caution must be exercised when older children (2-12 years) are treated. Children affected with viral flu, chickenpox, or viral fever should avoid using NISE D SPRAY as it contains methyl salicylate may induce Reyes Syndrome (swelling in the liver and brain).

Uses of NISE D SPRAY

Musculoskeletal pain, Joint pain of arthritis

Directions for Use

NISE D SPRAY is for use on the skin surface (topical use) only. Do not apply to open wounds, external heat, or occlusive dressings to the treated joints. Avoid contact with eyes and mucous membranes. Cream/Ointment/Gel: It should be applied to the affected area with a piece of clean cotton wool or gauze swab. Before applying, wash your hands with soap and water and then gently rub it on the affected areas. Avoid taking a shower for at least 1 hour after the application.Spray: Spray it on the affected areas of the skin and gently rub it into the skin.

Medicinal Benefits

NISE D SPRAY contains Diclofenac and Methyl salicylate (as a pain killer), Linseed oil (as anti-inflammatory), and Menthol (as cooling agent). NISE D SPRAY works by first cooling the skin and then warming it up that interferes with the pain signal transmission through nerves. Together NISE D SPRAY works by blocking the release of chemical messengers that causes pain and inflammation with redness and swelling.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before using NISE D SPRAY, tell your doctor if you are allergic to NISE D SPRAY other pain killers (like ibuprofen, naproxen, celecoxib) or if you have any other allergies. Use of NISE D SPRAY is contraindicated in the people who have asthma, liver disease, kidney disease, stomach/intestine problems (bleeding, ulcers, Crohn's disease), cardiovascular diseases (heart attack, high blood pressure, stroke), swelling (oedema, fluid retention), blood disorders (such as anaemia), bleeding/clotting problems. NISE D SPRAY should not be given to children less than 2 years of age. The use of NISE D SPRAY should be done with caution in the elderly as they have a high risk of kidney damage and gastrointestinal bleeding.

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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FAQs

Sometimes drugs are not safe when you use them with certain other drugs and food. Taking them together can cause unpleasant side effects. Be sure to talk to your doctor about all the drugs you take.

Store in a dry and dark place at a temperature not exceeding 30°C. Do not freeze.

You should avoid the use of NISE D SPRAY if you have had any recent bypass heart surgery, heart attack, stroke, gastrointestinal bleeding (bloody stool), inflammation or ulcer of stomach/intestine. The elderly (more than 65 years of age) are at greater risk of having gastrointestinal bleeding so they should use NISE D SPRAY with caution.

No, NISE D SPRAY should be only used by the children who are more than 2 years of age. NISE D SPRAY is contraindicated in infants below 2 years of age.

No, use of NISE D SPRAY is contraindicated on the broken or cut wound skin. It should be only applied topically on the uppermost skin surfaces (epidermis). It should not be applied in the nostrils, vagina, or anus.

Drug-Drug Interactions Checker List

  • CAPTOPRIL
  • LISINOPRIL
  • LOSARTAN
  • VALSARTAN
  • CIDOFOVIR
  • DEXAMETHASONE
  • PREDNISONE
  • LITHIUM
  • METHOTREXATE
  • FUROSEMIDE

Special Advise

Caution should be exercised, it is advisable to consult a doctor before using it. “Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke.”

Disease/Condition Glossary

Osteoarthritis is a long term musculoskeletal joint disorder that causes damage to the cartilage and surrounding tissues characterized by pain, swelling, stiffness, and loss of function. The joint disorder becomes common with ageing and wear and tear of joints. Pain, swelling, bony overgrowth, and stiffness can be observed that follows inactivity and disappears within 30 minutes when the joint is moved. The diagnosis of osteoarthritis is based on symptoms and X-rays of the affected joints. Its treatment includes exercises, an analgesic that reduce pain and improve function, and finally joint replacement or other surgery like total knee replacement.

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