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Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

NITAZOXANIDE-500MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nizonide 500 Tablet

Nizonide 500 Tablet belongs to the class of 'antiprotozoal and antiviral' drugs, primarily used to treat diarrhoea caused by parasite infections of the intestines (Cryptosporidium parvum and Giardia lamblia). Nizonide 500 Tablet also treats protozoa infections caused by single-cell parasites that live in moist places like lakes, streams, and soil. Diarrhoea is a condition that causes the frequent passing of loose or watery stools.

Nizonide 500 Tablet contains Nitazoxanide, which belongs to the class of drugs known as thiazolides. Nitazoxanide is a broad-spectrum anti-parasitic medication. It inhibits the production of chemical substances required for energy metabolism and growth of protozoa, helminths (worm-like parasites), anaerobic (microbes that survive without oxygen), and microaerophilic (requires little oxygen to survive)  and viruses. Nitazoxanide is effective in the treatment of gastrointestinal infections.

Please take Nizonide 500 Tablet in the dose and duration prescribed by your doctor based on your medical condition. Nizonide 500 Tablet is generally safe to use. However, some may experience side effects like nausea, vomiting, stomach pain, fever, hair loss, dizziness, giddiness, and headache. Most of these side effects of Nizonide 500 Tablet do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Inform your doctor if you have any liver or kidney diseases asthma, and weakened immune system before starting Nizonide 500 Tablet. If you are allergic to Nizonide 500 Tablet or any other medicines, please tell your doctor. Do not suddenly stop this medicine to avoid unpleasant side effects and sudden withdrawal symptoms. Intake of probiotics, prebiotics, and plenty of fluids is recommended if you are suffering from diarrhoea. Pregnant and breastfeeding women should use Nizonide 500 Tablet with proper consultation and caution. Do not drive or operate heavy machinery after taking Nizonide 500 Tablet as it may cause dizziness.

Uses of Nizonide 500 Tablet

Diarrhoea.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Dispersible tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Suspension/Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Nizonide 500 Tablet contains Nitazoxanide, which belongs to the class of drugs known as thiazolides. Nitazoxanide is a broad-spectrum anti-parasitic, antiprotozoal, and antiviral medication, primarily used to treat diarrhoea. It inhibits the production of chemical substances required for energy metabolism and growth of protozoa, helminths (worm-like parasites), anaerobic (microbes that survive without oxygen), and microaerophilic (requires little oxygen to survive) and viruses. Nitazoxanide is effective in the treatment of gastrointestinal parasite infections, including Cryptosporidium parvum and Giardia lamblia.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nizonide 500 Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Drug Warnings

Inform your doctor if you have any liver or kidney diseases, asthma, diabetes, and a weakened immune system before starting Nizonide 500 Tablet. If you are allergic to Nizonide 500 Tablet or any other medicines, please tell your doctor. Do not take Nizonide 500 Tablet on your own since it may lead to antibiotic-resistance failing the antibiotics to act against specific infections. Do not suddenly stop this medicine to avoid unpleasant side effects and sudden withdrawal symptoms. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Nizonide 500 Tablet. Do not drive or operate heavy machinery after taking Nizonide 500 Tablet as it may cause dizziness. Nizonide 500 Tablet is not recommended for children less than one year of age. 

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas.
  • Avoid foods rich in calcium, grapefruit, and grapefruit juice as they might hinder antibiotic's absorption.
  • If you have diarrhoea try to drink appropriate amounts of fluids to avoid dehydration. 
  • If you have minor diarrhoea (less than four stools daily) drinking caffeine-free soft drinks, juices or sport rehydration drinks can be sufficient. 
  • If the diarrhoea is more severe, specially formulated rehydration drinks should be taken.
  • Avoid alcoholic beverages with Nizonide 500 Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Nizonide 500 Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIPROTOZOALS

Author Details

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Drug-Diseases Interactions

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FAQs

Nizonide 500 Tablet contains Nitazoxanide. It is an antiprotozoal and antiviral drug that inhibits the production of chemical substances required for energy metabolism and growth of parasites, thus treating diarrhoea.

Please let your doctor know if you have a history of allergic reactions to medicines, liver or kidney diseases, asthma, weakened immune system, and diabetes before starting Nizonide 500 Tablet.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Do not stop using Nizonide 500 Tablet even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the infection may not be cured completely.

Drug-Drug Interactions Checker List

  • WARFARIN
  • LORAZEPAM
  • VALPROIC ACID

Disease/Condition Glossary

Diarrhoea is a condition that causes the frequent passing of loose or watery stools. It is caused by bacteria (campylobacter and Escherichia coli), virus (norovirus or rotavirus), and parasites in contaminated food and water. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks. Diarrhoea can be due to an infection, antibiotics, a disease (inflammatory bowel disease), and other medicines.

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