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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nobel Plus Tablet

Nobel Plus Tablet belongs to a class of medicines known as 'non-steroidal anti-inflammatory drugs (NSAIDs)', primarily indicated in the treatment of mild to moderate pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. Nobel Plus Tablet relieves symptoms of arthritis, dysmenorrhea (painful periods or menstrual cramps) and reduces fever. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. While, chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, mild migraine, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. Besides this, it is also useful for dental pain, which can occur due to damage to the tooth nerve, infection, decay, extraction or injury.

Nobel Plus Tablet is composed of two medicines: Nimesulide and Acetaminophen. Nimesulide is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Acetaminophen acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Together it helps in reducing mild to moderate pain in a shorter duration.

Take Nobel Plus Tablet as prescribed by your doctor. You are advised to take Nobel Plus Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Like all medicines, Nobel Plus Tablet may cause side effects, although not everybody gets them. Stop taking this medicine if you experience symptoms like chest tightness, breathing difficulties, fever, skin rashes, increased heart rate, and or in case of any signs of hypersensitivity.

Do not take Nobel Plus Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Nobel Plus Tablet may be associated with a small increase in heart attack risk (myocardial infarction). Avoid alcohol consumption as it may damage your liver and cause increased side effects from taking this drug. Consult your doctor if your pain, inflammation and fever symptoms do not disappear even after ten days. Nobel Plus Tablet is usually safe to be taken in pregnancy and breastfeeding females, however, an individual should consult their doctor before taking it. Nobel Plus Tablet is well tolerated by elderly persons.

Uses of Nobel Plus Tablet

Pain relief

Directions for Use

Nobel Plus Tablet can be taken with or after the meal. It should be swallowed as a whole with a glass of water. Do not crush or chew it. Do not take Nobel Plus Tablet if your pain lasts for more than ten days or fever stays for more than three days, and consult your doctor immediately. Do not take a double dose if you missed one dose.

Medicinal Benefits

Nobel Plus Tablet is composed of nimesulide and acetaminophen, primarily used to treat mild to moderate pain. Nobel Plus Tablet is prescribed mainly to treat pain and get relief from discomfort caused by conditions like mild migraine, tooth pain, arthritis, period pain, back pain, cold/ flu pain and other types of short-term pains. Acetaminophen has got the advantage of producing less gastric irritation compared to other painkillers like aspirin.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Please inform your doctor before starting Nobel Plus Tablet if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery or severe kidney/liver impairment. Nimesulide present in Nobel Plus Tablet is known to affect fertility, so if you are planning for pregnancy contact doctor. Nobel Plus Tablet should be avoided in both pregnant (especially last trimester of pregnancy) and breastfeeding women, as it may pass the milk affecting the baby. Patients with heart diseases and recent stroke (bleeding in the brain) should not take Nobel Plus Tablet as a substitute for aspirin. It should not be given to children (below 12 years) with symptoms of fever and chills or suffering from influenza (flu) or chickenpox.

Drug-Drug Interactions

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ParacetamolLomitapide
Severe
ParacetamolMipomersen
Severe

Drug-Drug Interactions

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ParacetamolLomitapide
Severe
How does the drug interact with Nobel Plus Tablet:
Co-administration of Lomitapide and Nobel Plus Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Nobel Plus Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Nobel Plus Tablet:
Co-administration of Mipomersen with Nobel Plus Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Nobel Plus Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nobel Plus Tablet:
Co-administration of Nobel Plus Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Nobel Plus Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Nobel Plus Tablet:
Co-administration of Teriflunomide with Nobel Plus Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Nobel Plus Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nobel Plus Tablet:
Co-administration of Nobel Plus Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Nobel Plus Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Nobel Plus Tablet:
Co-administration of Nobel Plus Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Nobel Plus Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
How does the drug interact with Nobel Plus Tablet:
Co-administration of ketamine and Nobel Plus Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Nobel Plus Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nobel Plus Tablet:
Co-administration of Nobel Plus Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Nobel Plus Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize chemical cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

It is advised not to take Nobel Plus Tablet if you planning to get pregnant as it contains nimesulide, which may affect your fertility. So, before starting Nobel Plus Tablet , please consult your doctor.

It is advised not to take Nobel Plus Tablet as a long term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results of Nobel Plus Tablet , take it in doses and duration mentioned by your doctor.

Yes, Nobel Plus Tablet should be preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and upset stomach.

You should not take Nobel Plus Tablet if you have a history of peptic ulceration, a history of gastrointestinal hemorrhage, Crohn's disease or ulcerative colitis.

You should avoid intake of Nobel Plus Tablet if you are allergic to Nobel Plus Tablet , nimesulide or paracetamol, a regular heavy alcohol drinker, liver disease (increased liver enzyme), any type of recent ulcer or bleeding, suffering from flu or fever (with chills), in the last trimester of pregnancy or breastfeeding mother.

No, Nobel Plus Tablet does not treat migraine, it is used to relive from symptoms of mild migraine.

Drug-Drug Interactions Checker List

  • LITHIUM
  • METHOTREXATE
  • WARFARIN
  • ASPIRIN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • FUROSEMIDE
  • PREDNISONE
  • CIPROFLOXACIN
  • THEOPHYLLINE
  • EPHEDRINE
  • CYCLOSPORINE
  • DULOXETINE

Special Advise

Inform your doctor about any bleeding disorders as nimesulide in Nobel Plus Tablet should be taken with care as it may interference in the functioning of platelets.

Disease/Condition Glossary

Pain can be short term (acute) or long term (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. At the same time, chronic pain lasts for longer duration, it is caused due to pathologies like nerve damage, migraine, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, Osteoarthritis is a degenerative disease that results in chronic pain in joints (especially the knee) and stiffness making daily tasks difficult.

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