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  3. Nucala 100 mg Injection 1 ml

Nucala 100 mg Injection 1 ml, Pack of 1 Injection
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

MEPOLIZUMAB-100MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Nucala 100 mg Injection 1 ml

Nucala 100 mg Injection 1 ml belongs to the class of 'immunomodulators', primarily used to treat asthma. Asthma is a respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. Nucala 100 mg Injection 1 ml is used as an add-on maintenance treatment in severe asthma patients above six years of age and in patients with chronic rhinosinusitis with nasal polyps. It is also used in the treatment of hypereosinophilic syndrome and eosinophilic granulomatosis.

Nucala 100 mg Injection 1 ml consists of Mepolizumab as an active ingredient, which binds itself to interleukin-5 (IL-5) and stops it from attaching to its receptor on the surface of eosinophil white blood cells, specifically the alpha subunit of the receptor. It works by preventing the body's natural production of certain chemicals that increase asthma symptoms, like coughing, wheezing, chest pain, and breathing difficulties.

Nucala 100 mg Injection 1 ml may cause common side effects such as fever, back pain, itching, headache, sore throat, and breathing difficulty. These side effects resolve over time. Inform your doctor if any of these side effects bother you. Nucala 100 mg Injection 1 ml will be administered by a healthcare professional. Do not self-administer

Avoid taking Nucala 100 mg Injection 1 ml and inform your doctor if you are allergic to any component present in it. Before starting Nucala 100 mg Injection 1 ml, inform your doctor if you have any liver or kidney disease or active parasitic infections and are taking any inhaled corticosteroids. Pregnant and breastfeeding mothers should inform the physician before starting treatment with Nucala 100 mg Injection 1 ml. This medicine is contraindicated in cases of bronchospasm or status asthmaticus.

Uses of Nucala 100 mg Injection 1 ml

Asthma.

Directions for Use

A trained healthcare professional will administer it. Do not self-administer.

Medicinal Benefits

Nucala 100 mg Injection 1 ml contains Mepolizumab, which is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody. It works by preventing the body's natural production of certain chemicals that increase asthma symptoms, like coughing, wheezing, chest pain, and breathing difficulties.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nucala 100 mg Injection 1 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep. This helps the body fight infection.
  • Keep yourself hydrated by drinking enough water and other fluids.
  • Wash your hands often and avoid touching your eyes, mouth or nose.
  • Wear a mask whilst going out.
  • Warm steam or a hot shower may help with nose secretions.
  • Avoid contact with others to prevent contamination.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.

Drug Warnings

To treat your condition effectually, continue taking Nucala 100 mg Injection 1 ml for the period that your doctor has prescribed. Avoid taking Nucala 100 mg Injection 1 ml if you are allergic to it or any other components present in it. Inform your doctor if you have any liver or kidney diseases, active parasitic infections, and are taking any inhaled corticosteroids before receiving Nucala 100 mg Injection 1 ml. Avoid close contact with people who have infections that can be easily spread. Nucala 100 mg Injection 1 ml is not recommended in children below six years of age as safety and efficacy are not established. Nucala 100 mg Injection 1 ml may cause severe allergic reactions, herpes zoster infections, and parasitic infections and reduce the effect of corticosteroid medicines. Hence, inform your doctor about your complete medication and medical history before taking Nucala 100 mg Injection 1 ml.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy and well-balanced diet.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Try including selenium-rich food sources like Brazil nuts, yellowfin tuna, rice, beans, whole-wheat bread, dairy products, ham, chicken, turkey, beef, eggs, pork, baked beans, mushrooms, oatmeal, and spinach.
  • Include zinc-rich sources like meat, shellfish, legumes, hemp seeds, nuts, eggs, dairy products, whole grains, potatoes, kale, and dark chocolate in your diet.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Nucala 100 mg Injection 1 ml Substitute

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Author Details

Lakshmithulasi YarraguntaDoctor badge

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:50 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nucala 100 mg Injection 1 ml contains Mepolizumab, which reduces the synthesis of pro-inflammatory markers called cytokines. Thus, it helps in decreasing inflammation.

Drug-Drug Interactions Checker List

  • DEUCRAVACITINIB

Special Advise

The doctor may suggest some tests to know the root cause of the respiratory disorder, such as Spirometry (check the narrowing of bronchial tubes) and Peak flow (check how difficult it is to exhale).

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The treatment for asthma includes medication, breathing exercises and self-care.

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