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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Nudoxa 50Mg/ 25Ml Inj

Nudoxa 50Mg/ 25Ml Inj is an anti-cancer medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Nudoxa 50Mg/ 25Ml Inj is primarily used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast). It is also used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children).

Nudoxa 50Mg/ 25Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis.

Nudoxa 50Mg/ 25Ml Inj may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, red discoloration of urine, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Nudoxa 50Mg/ 25Ml Inj. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Nudoxa 50Mg/ 25Ml Inj should be avoided if you are allergic to it or any other components of this medicine. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression, and severe liver disease. Hence, if you have any such conditions, inform your doctor. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause adverse effects. Nudoxa 50Mg/ 25Ml Inj is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

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Whats That

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Non returnable*
COD available

Online payment accepted

Synonym

DOXORUBICIN HYDROCHLORIDE

Composition

DOXORUBICIN-50MG

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Nudoxa 50Mg/ 25Ml Inj

Breast Cancer

Medicinal Benefits

Nudoxa 50Mg/ 25Ml Inj contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Nudoxa 50Mg/ 25Ml Inj is also used in the treatment of acute lymphoblastic leukaemia, acute myeloblastic leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms’ tumour, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma

Side Effects of Nudoxa 50Mg/ 25Ml Inj

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection
  • Red discolouration of urine
  • Loss of appetite
  • Mouth sores
  • Tiredness
  • Weight gain

Directions for Use

A trained healthcare professional will administer Nudoxa 50Mg/ 25Ml Inj. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Nudoxa 50Mg/ 25Ml Inj should be avoided if you are allergic to it. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression and severe liver disease. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause serious adverse effects. Nudoxa 50Mg/ 25Ml Inj is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Do not stop receiving Nudoxa 50Mg/ 25Ml Inj without a doctor’s advice, as it can cause serious health conditions. Nudoxa 50Mg/ 25Ml Inj is known to cause secondary malignancies, tissue necrosis, cardiomyopathy and septic shock in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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DoxorubicinZiprasidone
Critical
DoxorubicinBaricitinib
Severe

Drug-Drug Interactions

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DoxorubicinZiprasidone
Critical
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Coadministration of Nudoxa 50Mg/ 25Ml Inj with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Nudoxa 50Mg/ 25Ml Inj is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DoxorubicinBaricitinib
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Using baricitinib together with Nudoxa 50Mg/ 25Ml Inj may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Nudoxa 50Mg/ 25Ml Inj if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
DoxorubicinEfavirenz
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Taking Efavirenz and Nudoxa 50Mg/ 25Ml Inj can increase the risk or severity of irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Nudoxa 50Mg/ 25Ml Inj together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxorubicinTofacitinib
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Taking Tofacitinib with Nudoxa 50Mg/ 25Ml Inj may increase the risk of serious infection.

How to manage the interaction:
Although taking Tofacitinib and Nudoxa 50Mg/ 25Ml Inj together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. It is important to keep a close eye on your condition. Do not stop using any medications without a doctor's advice.
DoxorubicinHydroxychloroquine
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
The combined use of Nudoxa 50Mg/ 25Ml Inj and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Nudoxa 50Mg/ 25Ml Inj and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DoxorubicinMifepristone
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Co-administration of Nudoxa 50Mg/ 25Ml Inj with mifepristone can increase the risk of irregular heart rhythms. Prolonged treatment with Mifepristone may result in low potassium levels.

How to manage the interaction:
Taking Nudoxa 50Mg/ 25Ml Inj with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
DoxorubicinClozapine
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Taking Nudoxa 50Mg/ 25Ml Inj and clozapine may increase the risk of neutropenia.

How to manage the interaction:
Co-administration of Nudoxa 50Mg/ 25Ml Inj with Clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - like a severe infection, fever, diarrhea, sore throat, muscle pain, or difficulty breathing - it's important to call your doctor right away." Do not discontinue any medications without first consulting your doctor.
DoxorubicinCeritinib
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Taking Nudoxa 50Mg/ 25Ml Inj with Ceritinib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Ceritinib with Nudoxa 50Mg/ 25Ml Inj together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
DoxorubicinInfliximab
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Combining Infliximab with Nudoxa 50Mg/ 25Ml Inj can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Nudoxa 50Mg/ 25Ml Inj can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
DoxorubicinSotalol
Severe
How does the drug interact with Nudoxa 50Mg/ 25Ml Inj:
Using Nudoxa 50Mg/ 25Ml Inj together with sotalol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Nudoxa 50Mg/ 25Ml Inj, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PHENYTOIN
  • PHENOBARBITAL
  • RIFAMPICIN
  • CLARITHROMYCIN
  • VORICONAZOLE
  • CYCLOSPORIN
  • BUPROPION
  • PAROXETINE
  • FLUOXETINE
  • DEXAMETHASONE
  • HALOPERIDOL

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

  • Avoid intercourse while on treatment with Nudoxa 50Mg/ 25Ml Inj.
  • Regular complete blood count monitoring is advised.  Also, monitoring of liver function is important while receiving Nudoxa 50Mg/ 25Ml Inj.
  • According to postmarketing reports, juvenile children receiving doxorubicin hydrochloride are at risk of developing late cardiovascular dysfunction. Risk factors include early age during treatment (particularly five years), large cumulative dosages, and receipt of multimodal modality therapy. All pediatric patients who have received doxorubicin hydrochloride should undergo long-term cardiovascular monitoring.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin. 

Lymphoma: Lymphoma is a wide word for cancer that develops in lymph system cells. Hodgkin lymphoma and non-Hodgkin lymphoma (NHL) are the two most common kinds. Hodgkin lymphoma is frequently curable.

Nudoxa 50Mg/ 25Ml Inj Substitute

Substitutes safety advice
  • Orcamycin 50Mg Injection

    by AYUR

    810.00per tablet
  • Zodox 50 Injection 1's

    800.10per tablet
  • Pegadria 50 Injection 25 ml

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  • Doxulip 50 Injection 25 ml

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  • Doxilyd 50 mg Injection 1's

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