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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ARIPIPRAZOLE-2.5MG

Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nulet-2.5 MD Tablet

Nulet-2.5 MD Tablet belongs to a class of drugs called antipsychotics and mood stabilizers primarily used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Nulet-2.5 MD Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused due to disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Nulet-2.5 MD Tablet contains Aripiprazole which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Nulet-2.5 MD Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Nulet-2.5 MD Tablet improves mood swings, depression, and other psychotic problems. 

Take Nulet-2.5 MD Tablet as prescribed. Your doctor will advise you how often you take Nulet-2.5 MD Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Nulet-2.5 MD Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Nulet-2.5 MD Tablet or any other medicines, please tell your doctor. Nulet-2.5 MD Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Nulet-2.5 MD Tablet if you are pregnant or breastfeeding and consult a doctor. Nulet-2.5 MD Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Nulet-2.5 MD Tablet , please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Nulet-2.5 MD Tablet . 

Uses of Nulet-2.5 MD Tablet

Schizophrenia, Mania, Bipolar disorder

Directions for Use

Tablet: Take it with or without food as advised by the doctor and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Nulet-2.5 MD Tablet contains Aripiprazole which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Nulet-2.5 MD Tablet inhibits the dopamine receptor in our brain thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Nulet-2.5 MD Tablet improves overall behavior and thoughts and helps in having a better social life and comfortably doing daily activities. Nulet-2.5 MD Tablet may be used in combination with other medicines to treat depression. Additionally, Nulet-2.5 MD Tablet is also used to reduce unwanted sounds (tics) severity in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements). 

Storage

Store in a cool and dry place away from sunlight
Side effects of Nulet-2.5 MD Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.

Drug Warnings

If you are allergic to Nulet-2.5 MD Tablet or any other medicines, please tell your doctor. Nulet-2.5 MD Tablet should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Nulet-2.5 MD Tablet if you are pregnant or breastfeeding and consult a doctor. Nulet-2.5 MD Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Nulet-2.5 MD Tablet , please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Nulet-2.5 MD Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Nulet-2.5 MD Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nulet-2.5 MD Tablet:
Co-administration of Metoclopramide with Nulet-2.5 MD Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Nulet-2.5 MD Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nulet-2.5 MD Tablet:
Coadministration of Nulet-2.5 MD Tablet and primidone may decrease the blood levels of Nulet-2.5 MD Tablet, which may make Nulet-2.5 MD Tablet less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between primidone and Nulet-2.5 MD Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nulet-2.5 MD Tablet:
Combining Nulet-2.5 MD Tablet with Mirabegron can increase the levels of Nulet-2.5 MD Tablet in the body. This can lead to increased risk or severity of side effects.

How to manage the interaction:
Although taking Mirabegron and Nulet-2.5 MD Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs like feeling sleepy, having seizures, unusual muscle movements, low blood pressure, feeling confused, muscle spasms, twitching in your jaw, shaking or jerking in your arms and legs, feeling nervous or restless, dizziness, lightheaded, or fainting contact the doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleIopamidol
Severe
How does the drug interact with Nulet-2.5 MD Tablet:
Coadministration of Nulet-2.5 MD Tablet and Iopamidol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although taking Nulet-2.5 MD Tablet and Iopamidol together can cause an interaction, it can be taken if a doctor has suggested it. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nulet-2.5 MD Tablet:
Using ketamine together with Nulet-2.5 MD Tablet may increase risk of side effects.

How to manage the interaction:
Co-administration of Ketamine with Nulet-2.5 MD Tablet can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how you're breathing. If you notice any of these signs - feeling dizzy, tired, confused, having trouble focusing, feeling too sleepy, or having trouble breathing - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nulet-2.5 MD Tablet:
Combining Nulet-2.5 MD Tablet with Clozapine can increase the risk of heart problmes including low blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Nulet-2.5 MD Tablet and Clozapine, but it can be taken if prescribed by a doctor. However, if you experience dizziness, drowsiness, blurred vision, confusion, dry mouth, stomach pain, constipation, difficulty urinating, heat intolerance, heart palpitation, or irregular heart rhythm, consult the doctor. Be careful while getting up from a lying position. Avoid activities requiring mental alertness like operating dangerous machinery or driving. Do not stop using any medications without talking to a doctor.
AripiprazoleFosphenytoin
Severe
How does the drug interact with Nulet-2.5 MD Tablet:
When Nulet-2.5 MD Tablet and Fosphenytoin are taken together, can reduce the levels of Nulet-2.5 MD Tablet levels in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Nulet-2.5 MD Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nulet-2.5 MD Tablet:
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Nulet-2.5 MD Tablet.

How to manage the interaction:
Co-administration of Nulet-2.5 MD Tablet with Topiramate can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness, consult the doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced sweating or a fever. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nulet-2.5 MD Tablet:
Using Tapentadol together with Nulet-2.5 MD Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Nulet-2.5 MD Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
AripiprazoleIomeprol
Severe
How does the drug interact with Nulet-2.5 MD Tablet:
Coadministration of Nulet-2.5 MD Tablet and Iohexol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although there is a possible interaction between Nulet-2.5 MD Tablet and Iomeprol, you can take these medicines together if prescribed by a doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Nulet-2.5 MD Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Nulet-2.5 MD Tablet may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nulet-2.5 MD Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and prevents its overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbelief and unfriendliness) of schizophrenia. Also, Nulet-2.5 MD Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Thereby, Nulet-2.5 MD Tablet improves behaviour, thoughts and helps in having a better social life and enables to comfortably do daily activities.

No, you are not recommended to take Nulet-2.5 MD Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Nulet-2.5 MD Tablet in the blood leading to increased adverse effects. However, please consult a doctor before taking Nulet-2.5 MD Tablet with other medicines.

Nulet-2.5 MD Tablet may cause weight gain in some patients but it is not necessary for everyone taking Nulet-2.5 MD Tablet to experience this side effect. However, in order to avoid gaining weight while taking Nulet-2.5 MD Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

Nulet-2.5 MD Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Nulet-2.5 MD Tablet .

Yes, Nulet-2.5 MD Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Nulet-2.5 MD Tablet and inform your doctor if you have diabetes before taking Nulet-2.5 MD Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.

No, you are not recommended to stop taking Nulet-2.5 MD Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Nulet-2.5 MD Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Nulet-2.5 MD Tablet , please consult your doctor so that the dose may be gradually reduced.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • OLANZAPINE
  • FLUOXETINE
  • PAROXETINE
  • VENLAFAXINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • AMIODARONE
  • FLECAINIDE
  • QUINIDINE
  • NEVIRAPINE
  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • IBUPROFEN
  • RIFAMPICIN
  • RIFABUTIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Special Advise

  • Elderly patients more than 65 years with dementia-related psychosis treated with Nulet-2.5 MD Tablet can be at an increased risk of death. 
  • Nulet-2.5 MD Tablet is not prescribed and approved for the treatment of dementia-related psychosis. 
  • Increased risk of suicidal thinking and behavior changes has been observed in children, adolescents, and young adults taking Nulet-2.5 MD Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.  

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or sleep pattern changes, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

Bipolar disorder: It is also called manic depression, associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, low energy). Bipolar disorder involves lifelong treatment. 

Depression: It is a mental condition characterized by low mood and a loss of interest in activities. People affected by this condition are often unsocial and try to keep isolated from other social activities. 

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