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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Numlo-TM Tablet

Numlo-TM Tablet belongs to the class of medicines called ‘anti-hypertensive’ primarily used to treat hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart diseases, irregular heartbeat and other complications.

Numlo-TM Tablet is a combination of two medicines include: S-Amlodipine and Telmisartan, which are antihypertensive medicines. S-Amlodipine is a calcium channel blocker and works by relaxing and widening the blood vessels.  It is equally efficacious at a half dose with better tolerability, and fewer side effects include peripheral oedema than amlodipine. Telmisartan is an angiotensin II receptor antagonist that lowers blood pressure and increases blood flow by preventing blood vessel's narrowing. It is used to lower the chances of stroke, heart attack and death. Altogether, Numlo-TM Tablet helps to lower high blood pressure, chest pain (angina) and other conditions caused by coronary artery disease.

Take Numlo-TM Tablet as prescribed by your doctor. You are advised to take Numlo-TM Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain side effects dizziness, stomach pain, nausea, constipation, double vision, muscle cramps, swollen ankles, oedema (fluid retention), hypotension (low blood pressure). Most of these side effects of Numlo-TM Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Numlo-TM Tablet or any other medicines, please inform your doctor. Pregnant or breastfeeding women should discontinue this Numlo-TM Tablet because it can cause injury and death to the developing fetus. Please do not stop taking Numlo-TM Tablet on your own, which may lead to the recurrence of symptoms or worsen the condition. Rise slowly if you have been sitting or lying down as it may cause you to feel lightheaded or weak, especially when you stand up. Avoid potassium supplements with Numlo-TM Tablet as it may lead to high potassium levels in the blood. It is advised to drive with caution after taking Numlo-TM Tablet as it usually causes drowsiness and affects the driving ability.

Uses of Numlo-TM Tablet

Hypertension (high blood pressure)

Directions for Use

Swallow Numlo-TM Tablet as a whole with a glass of water. Do not crush or chew it.

Medicinal Benefits

Numlo-TM Tablet is a combination of two medicines, namely: S-Amlodipine and Telmisartan primarily taken to prevent hypertension (high blood pressure). S-Amlodipine belongs to a group of drugs called calcium channel blocker that dilates (widens) blood vessels and increases blood flow. S-amlodipine is equally effective at a half dose with better tolerability and lesser side effects include peripheral oedema than amlodipine. Telmisartan is an angiotensin receptor blocker (ARB) that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II (that tightens your blood vessels). It allows these constricted blood vessels to relax and therefore helps lower high blood pressure. It is used to lower the chances of stroke, heart attack and death. Collectively, Numlo-TM Tablet helps to lower high blood pressure, chest pain (angina), and other conditions caused by coronary artery disease.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Don't stop taking Numlo-TM Tablet without talking to your doctor first. Stopping Numlo-TM Tablet abruptly may cause changes in your blood pressure and heart rhythm, cause chest pain or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. Numlo-TM Tablet should not be given to the people allergic to Numlo-TM Tablet or any of its ingredients, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease. Do not take Numlo-TM Tablet if you are pregnant, planning to conceive, or breastfeeding. Numlo-TM Tablet is not recommended to children below 18 years. Numlo-TM Tablet can cause ankle or foot swelling, raise your legs while you are sitting down and talk to your doctor if it does not go away. Avoid potassium supplements with Numlo-TM Tablet as it may lead to high potassium levels in the blood. Do not consume alcohol with Numlo-TM Tablet as it may increase the risk of low blood pressure.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Numlo-TM Tablet:
Co-administration of Aliskiren with Numlo-TM Tablet can increase the risk of hyperkalemia (high potassium levels in the blood).

How to manage the interaction:
Taking Numlo-TM Tablet with Aliskiren can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Numlo-TM Tablet:
Taking Numlo-TM Tablet with benazepril may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, Numlo-TM Tablet can be taken with benazepril if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medication without consulting a doctor.
TelmisartanPotassium acetate
Severe
How does the drug interact with Numlo-TM Tablet:
Co-administration of Potassium acetate can make Numlo-TM Tablet more likely to cause high levels of potassium in the blood.

How to manage the interaction:
Although taking Potassium acetate and Numlo-TM Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Numlo-TM Tablet:
Taking trimethoprim with Numlo-TM Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although there is an interaction between Numlo-TM Tablet and trimethoprim, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, and a weak pulse. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Numlo-TM Tablet:
Taking spironolactone with Numlo-TM Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction, Numlo-TM Tablet can be taken with spironolactone if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
TelmisartanPotassium citrate
Severe
How does the drug interact with Numlo-TM Tablet:
Taking Potassium citrate with Numlo-TM Tablet together may increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although taking Potassium citrate with Numlo-TM Tablet together can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Numlo-TM Tablet:
Co-administration of amiloride with Numlo-TM Tablet may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm).

How to manage the interaction:
Although there is a possible interaction, amiloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Numlo-TM Tablet:
Taking perindopril with Numlo-TM Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, Numlo-TM Tablet can be taken with perindopril if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Numlo-TM Tablet:
Taking quinapril with Numlo-TM Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, Numlo-TM Tablet can be taken with quinapril if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium, such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Numlo-TM Tablet:
Taking ramipril with Numlo-TM Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and high blood potassium.

How to manage the interaction:
Although there is a possible interaction, Numlo-TM Tablet can be taken with ramipril if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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S AMLODIPINE-2.5MG+TELMISARTAN-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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S AMLODIPINE-2.5MG+TELMISARTAN-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming high potassium-containing foods while taking S-amlodipine and telmisartan can cause high levels of potassium in the blood, increasing the risk of side effects such as weakness, an irregular heartbeat, confusion, or feelings of heaviness in the legs. Limit or avoid high potassium-containing foods when using S-amlodipine and telmisartan, as they may cause an interaction.

Diet & Lifestyle Advise

  • ​​Keep your weight under control with BMI 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Numlo-TM Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Numlo-TM Tablet is a combination of two medicines: S-Amlodipine and Telmisartan. S-Amlodipine is a calcium channel blocker (CCB) and Telmisartan is an angiotensin receptor blocker (ARB). They work by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body. Together, they lower blood pressure effectively.

Numlo-TM Tablet not recommended to take if you are pregnant as it can cause damage to the unborn baby (may lead to fetal toxicity). It contains telmisartan, a category D pregnancy drug and it is harmful to the baby.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

Numlo-TM Tablet contains telmisartan which may increase potassium levels in the blood (hyperkalemia). Therefore, it is recommended to avoid the intake of potassium supplements and foods that are rich in potassium like coconut water, bananas and broccoli.

Yes, Numlo-TM Tablet contains S-amlodipine, which is known to cause ankle swelling upon long term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

Please inform your doctor before surgery if you are taking Numlo-TM Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with general anesthesia.

Drug-Drug Interactions Checker List

  • RAMIPRIL
  • ALISKIREN
  • SIMVASTATIN
  • VERAMAPIL
  • DILITAZEM
  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • INDINAVIR
  • NELFINAVIR
  • NEVIRAPINE
  • IBUPROFEN
  • NAPROXEN
  • ASPIRIN
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • RIFAMPICIN
  • RIFABUTIN
  • DIGOXIN
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • LITHIUM
  • CYCLOSPORINE
  • TACROLIMUS

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor. 
  • Do not use potassium supplements or salt substitutes while using Numlo-TM Tablet unless your doctor has told you to do so.
  • Numlo-TM Tablet may cause swelling in the ankles and feet, try to avoid sitting for long times or maintain limb elevation while sitting.

Disease/Condition Glossary

Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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