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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Solvate Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nurogabin-NT 400/10 Tablet

Nurogabin-NT 400/10 Tablet is a combination medicine indicated for the management of neuropathic pain. It is a chronic progressive nerve disease that causes nerve pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

Nurogabin-NT 400/10 Tablet contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, dry mouth, and tingling sensations. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Nurogabin-NT 400/10 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Nurogabin-NT 400/10 Tablet should not be given to children unless prescribed by the doctor. Avoid consuming alcohol along with Nurogabin-NT 400/10 Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Nurogabin-NT 400/10 Tablet

Neuropathic pain

Directions for Use

Take Nurogabin-NT 400/10 Tablet with or without food. Swallow Nurogabin-NT 400/10 Tablet as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Nurogabin-NT 400/10 Tablet is used to treat neuropathic pain. Nurogabin-NT 400/10 Tablet is a combination of two drugs: Gabapentin and Nortriptyline. Gabapentin belongs to a class of drugs called anti-convulsants whereas Nortriptyline belongs to tricyclic antidepressants. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Nortriptyline works by preventing the released chemical messenger in brains (serotonin and noradrenaline) from being reabsorbed back into the nerve cells (neuron) in the brain. As a result, it prolongs the effect of serotonin and noradrenaline in the brain and prevents the movement of pain signals in the brain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Nurogabin-NT 400/10 Tablet if you are allergic to any of its contents. Inform your doctor before taking Nurogabin-NT 400/10 Tablet if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Nurogabin-NT 400/10 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Nurogabin-NT 400/10 Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nurogabin-NT 400/10 Tablet:
Taking Pentazocine with Nurogabin-NT 400/10 Tablet can increase the risk of serious side effects.

How to manage the interaction:
Although taking Pentazocine and Nurogabin-NT 400/10 Tablet together can evidently cause an interaction, but it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Using Ketamine together with Nurogabin-NT 400/10 Tablet may increase side effects.

How to manage the interaction:
Although taking Ketamine and Nurogabin-NT 400/10 Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Co-administration of Butorphanol and Nurogabin-NT 400/10 Tablet may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Nurogabin-NT 400/10 Tablet and Butorphanol, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GabapentinRemifentanil
Severe
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Combining Remifentanil with Nurogabin-NT 400/10 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Nurogabin-NT 400/10 Tablet with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GabapentinEsketamine
Severe
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Combining Nurogabin-NT 400/10 Tablet with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Nurogabin-NT 400/10 Tablet and Esketamine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Consult a doctor if you experience any symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not stop using any medications without a doctor's advice.
GabapentinSodium oxybate
Severe
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Taking Nurogabin-NT 400/10 Tablet with Sodium oxybate can increase the side effects on the central nervous system.

How to manage the interaction:
Although taking Nurogabin-NT 400/10 Tablet and Sodium oxybate together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - feeling tired, dizzy, lightheaded, confused, sad, having low blood pressure, or difficulty breathing - make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
GabapentinHydrocodone
Severe
How does the drug interact with Nurogabin-NT 400/10 Tablet:
When Hydrocodone is taken with Nurogabin-NT 400/10 Tablet, the amount of Hydrocodone in the blood may be reduced.

How to manage the interaction:
Although there is a possible interaction between Nurogabin-NT 400/10 Tablet and Hydrocodone, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GabapentinPethidine
Severe
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Combining Meperidine with Nurogabin-NT 400/10 Tablet can increase the risk of CNS depression.

How to manage the interaction:
Co-administration of Pethidine with Nurogabin-NT 400/10 Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Co-administration of Buprenorphine and Nurogabin-NT 400/10 Tablet may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Nurogabin-NT 400/10 Tablet and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Nurogabin-NT 400/10 Tablet:
Taking fentanyl with other drugs that cause central nervous system depression, such as Nurogabin-NT 400/10 Tablet, might result in an increased risk of adverse effects.

How to manage the interaction:
Although combining Fentanyl and Nurogabin-NT 400/10 Tablet may cause an interaction, they can be used if advised by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet.
  • Include cayenne pepper in your diet, as it can help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Nurogabin-NT 400/10 Tablet contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

To treat your condition effectually, continue taking Nurogabin-NT 400/10 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Nurogabin-NT 400/10 Tablet ; your doctor will reduce the dose gradually.

Nurogabin-NT 400/10 Tablet may cause dry mouth. In that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Nurogabin-NT 400/10 Tablet helps in the treatment of diabetic neuropathy (nerve damage in diabetic patients). However, please consult your doctor before starting Nurogabin-NT 400/10 Tablet if you have diabetes.

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Special Advise

  • If you are taking any antacids containing aluminum or magnesium, try to keep at least 2 hours gap between intake of Nurogabin-NT 400/10 Tablet and these antacids to avoid drug-drug interaction.
  • Nurogabin-NT 400/10 Tablet can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position

 

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is a chronic progressive nerve disease caused due to damage of sensory nerves. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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