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  3. Ocupol Eye/Ear Drop 5 ml

Ocupol Eye/Ear Drop 5 ml, Pack of 1
Ocupol Eye/Ear Drop 5 ml, Pack of 1
Ocupol Eye/Ear Drop 5 ml, Pack of 1
Ocupol Eye/Ear Drop 5 ml, Pack of 1
Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Composition :

CHLORAMPHENICOL-4MG + POLYMYXIN B-5000IU

Manufacturer/Marketer :

Centaur Pharmaceuticals Pvt Ltd

Consume Type :

EYE/EAR

Return Policy :

Not Returnable

Expires on or after :

About Ocupol Eye/Ear Drop 5 ml

Ocupol Eye/Ear Drop 5 ml is a combination medicine that belongs to a group of medicines called antibiotics primarily used in the treatment of surface ocular bacterial infections involving the cornea or conjunctiva. Also, it is used to treat superficial bacterial infections of the external auditory canal and infections of fenestration cavities and mastoidectomy (surgery to remove mastoid air cells, and air bubbles in the skull near the inner ears). Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Ocupol Eye/Ear Drop 5 ml does not work against infections caused by virus and fungus.

Ocupol Eye/Ear Drop 5 ml is a combination of two antibiotics namely: Polymyxin B and Chloramphenicol. Polymyxin B works by inhibiting the formation of bacterial cell walls, which are necessary for survival because they prevent unwanted substances from entering the cells and stop the leakage of cell contents. Chloramphenicol works by inhibiting the production of essential proteins required for bacteria to grow, multiply, and multiply. Bacteria are thus destroyed.

Use Ocupol Eye/Ear Drop 5 ml as prescribed by your doctor. Ocupol Eye/Ear Drop 5 ml is only for use in eyes/ears. Do not swallow or inject this medicine. You are advised to use Ocupol Eye/Ear Drop 5 ml for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience redness, itching, irritation, burning or stinging sensation at the application site, blurred vision, or dryness as side effects Ocupol Eye/Ear Drop 5 ml. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor. 

If you are allergic to Ocupol Eye/Ear Drop 5 ml or any other medicines, please tell your doctor. Ocupol Eye/Ear Drop 5 ml should be used in children only in doses prescribed by the doctor. Consult your doctor if you are pregnant or breastfeeding before using this medicine. Drive only if your vision is clear as Ocupol Eye/Ear Drop 5 ml may cause temporary blurred vision immediately after applying in the eyes. Ocupol Eye/Ear Drop 5 ml should be used with caution in cases of the perforated eardrum and in long-standing cases of chronic otitis media due to the possibility of ototoxicity (ear damage). If you are using any other drops or remedies in the ear, inform your doctor before using Ocupol Eye/Ear Drop 5 ml.

Uses of Ocupol Eye/Ear Drop 5 ml

Bacterial infections of eye or ear

Directions for Use

Ocupol Eye/Ear Drop 5 ml is only used in the eye/ear. Before and after use, thoroughly wash your hands with water. Instil the drops into the affected eye/ear using the dropper included with the pack. Based on your medical condition, your doctor will advise you on how many drops to administer. After use, replace the outer cap. Touching the tip of the container to the eye, eyelids, ear, or surrounding areas may contaminate Ocupol Eye/Ear Drop 5 ml.

Medicinal Benefits

Ocupol Eye/Ear Drop 5 ml contains Polymyxin B and Chloramphenicol used to treat bacterial infections of the eye and ear. Polymyxin B works by inhibiting the formation of bacterial cell walls, which are necessary for survival because they prevent unwanted substances from entering the cells and stop the leakage of cell contents. Chloramphenicol works by inhibiting the production of essential proteins required for bacteria to grow, multiply, and multiply. Bacteria such as Haemophilus influenzae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, Enterobacter aerogenes, Escherichia coli, Moraxella lacunate, Neisseria species and Streptococcus species are thus destroyed.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Ocupol Eye/Ear Drop 5 ml or any other medicines, please tell your doctor. Ocupol Eye/Ear Drop 5 ml should be used in children only in doses prescribed by your doctor. Consult your doctor if you are pregnant or breastfeeding before using Ocupol Eye/Ear Drop 5 ml. Drive only if your vision is clear as Ocupol Eye/Ear Drop 5 ml may cause temporary blurred vision immediately after applying in the eyes. You are recommended not to use contact lenses during the course of Ocupol Eye/Ear Drop 5 ml as it may worsen the infection. If you get any new eye problem, or eye infection or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain 10 minutes time gap between using Ocupol Eye/Ear Drop 5 ml and other eye drops. Ocupol Eye/Ear Drop 5 ml should be used with caution in cases of the perforated eardrum and in long-standing cases of chronic otitis media due to the possibility of ototoxicity (ear damage). Do not touch the tip of the container to the eye, eyelids, ear or surrounding areas as it may contaminate Ocupol Eye/Ear Drop 5 ml. If you are using any other drops or remedies in the ear, inform your doctor before using Ocupol Eye/Ear Drop 5 ml.

Drug-Drug Interactions

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ChloramphenicolTriazolam
Critical
ChloramphenicolLomitapide
Critical

Drug-Drug Interactions

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ChloramphenicolTriazolam
Critical
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Taking Ocupol Eye/Ear Drop 5 ml with triazolam can increased the effects of Ocupol Eye/Ear Drop 5 ml.

How to manage the interaction:
Taking Triazolam with Ocupol Eye/Ear Drop 5 ml is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. However, if you experience any unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
ChloramphenicolLomitapide
Critical
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Taking lomitapide with Ocupol Eye/Ear Drop 5 ml can significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Ocupol Eye/Ear Drop 5 ml with Lomitapide is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
ChloramphenicolFlibanserin
Critical
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Taking Flibanserin with Ocupol Eye/Ear Drop 5 ml may significantly increases the blood levels of flibanserin

How to manage the interaction:
Taking Ocupol Eye/Ear Drop 5 ml with Flibanserin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience dizziness, lightheadedness, and fainting. Do not discontinue any medication without consulting a doctor.
Polymyxin bEverolimus
Severe
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Taking Everolimus and Ocupol Eye/Ear Drop 5 ml together may increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Everolimus and Ocupol Eye/Ear Drop 5 ml, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bNeomycin
Severe
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
When Neomycin and Ocupol Eye/Ear Drop 5 ml are taken together, there is an increased possibility of severe side effects.

How to manage the interaction:
Taking Ocupol Eye/Ear Drop 5 ml with Neomycin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bBCG vaccine
Severe
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
When the BCG vaccine is used with Ocupol Eye/Ear Drop 5 ml, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Ocupol Eye/Ear Drop 5 ml and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
Polymyxin bNetilmicin
Severe
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Co-administration of Netilmicin with Ocupol Eye/Ear Drop 5 ml can increase the risk of side effects.

How to manage the interaction:
Co-administration of Netilmicin with Ocupol Eye/Ear Drop 5 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medications without a doctor's advice.
Polymyxin bStreptomycin
Severe
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Using Ocupol Eye/Ear Drop 5 ml together with streptomycin can increase the risk or severity of developing hearing loss, breathing problems, and kidney problems.

How to manage the interaction:
Although taking Ocupol Eye/Ear Drop 5 ml and Streptomycin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, hearing loss, ringing in the ears, vertigo, consult a doctor. Do not discontinue any medication without consulting a doctor.
Polymyxin bVecuronium
Severe
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Co-administration of Ocupol Eye/Ear Drop 5 ml and Vecuronium together may cause serious breathing problems.

How to manage the interaction:
Taking Ocupol Eye/Ear Drop 5 ml with Vecuronium together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any breathing difficulty, consult the doctor. Do not stop using any medications without a doctor's advice.
Polymyxin bIodamide
Severe
How does the drug interact with Ocupol Eye/Ear Drop 5 ml:
Co-administration of Iodamide with Ocupol Eye/Ear Drop 5 ml may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Ocupol Eye/Ear Drop 5 ml and Iodamide, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pain, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water frequently.
  • Keep your clothes, towels, and bedsheets separate from others.
  • Maintain good hygiene of contact lenses. Wash your hands thoroughly before wearing and after removing contact lenses.
  • Avoid wearing contact lenses while swimming. In case you use them mistakenly, get a new pair.
  • Wear protective eye gear if you are cycling or trekking through the forest.
  • If you have irritation in the eyes, avoid rubbing them.
  • Avoid getting things like shampoo, soap, and water into the ear, as it can cause itching.
  • Do not poke or scratch the ear, as it can cause damage to the ear canal, leading to inflammation. The inflamed skin can be infected by bacteria or fungi, which can cause infections in the ear.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Ocupol Eye/Ear Drop 5 ml Substitute

Substitutes safety advice

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:46 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ocupol Eye/Ear Drop 5 ml contains Polymyxin B and Chloramphenicol. Polymyxin B works by inhibiting the formation of bacterial cell walls, which are necessary for survival because they prevent unwanted substances from entering the cells and stop the leakage of cell contents. Chloramphenicol works by inhibiting the production of essential proteins required for bacteria to grow, multiply, and multiply. Bacteria are thus destroyed.

You are not recommended to wear contact lenses during the entire course of Ocupol Eye/Ear Drop 5 ml as it may worsen the infection. Therefore, you are advised to remove contact lenses before using Ocupol Eye/Ear Drop 5 ml and reinsert them after 24 hours of finishing the course of Ocupol Eye/Ear Drop 5 ml.

You are recommended to maintain a minimum of 10 minutes time gap between using Ocupol Eye/Ear Drop 5 ml and other eye drops and administer eye ointments in the last.

Yes, Ocupol Eye/Ear Drop 5 ml may cause temporary blurred vision when used in the eye. Therefore, you are recommended to wait until your vision is clear before driving or operating heavy machinery.

You are not recommended to stop using Ocupol Eye/Ear Drop 5 ml without consulting your doctor as abrupt stopping may increase pressure in the eyes and may lead to loss of vision. Therefore, use Ocupol Eye/Ear Drop 5 ml for as long as your doctor has prescribed it, and if you experience any difficulty while taking Ocupol Eye/Ear Drop 5 ml, please consult your doctor.

Special Advise

  • Please consult a doctor if your infection persists or worsens even after using Ocupol Eye/Ear Drop 5 ml for a week.

Disease/Condition Glossary

Bacterial eye infections: The common bacterial eye infections are conjunctivitis, stye, or keratitis. Conjunctivitis (pink eye) is the infection or inflammation of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that spreads by secretions of the eye. Symptoms include redness, itchy, and discharge or crusting around the eye. A stye, a bump on the eyelid, is also a common eye condition. Keratitis, inflammation of the cornea occurs due to frequent contact lenses, injury, diabetes, or surgery.  

Ear infections: An ear infection occurs when the fungi or bacteria affect the middle or outer ear, leading to pain and inflammation. Also, when the Eustachian tubes (small tubes that run from each ear to the back of the throat) become blocked or swollen, ear infections occur. Infection of the middle ear (air-filled space behind the eardrum) is known as otitis media whereas the inflammation of the external/outer ear canal that runs from the eardrum to the outside of the head is known as otitis externa. Ear infections can be painful due to inflammation and fluid build-up. Symptoms include discomfort or pain inside the ear, pus or fluid-like drainage from the ear, feeling of pressure inside the ear, and loss of hearing.

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