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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy

About OCUVIR OINTMENT 5GM

OCUVIR OINTMENT 5GM belongs to the class of 'antivirals' used to treat eye/ocular herpes and herpes simplex keratitis. Eye/ocular herpes is an eye infection caused by the herpes simplex virus. Herpes simplex keratitis is an eye infection caused when the herpes simplex virus affects the cornea (clear front surface of the eye).

OCUVIR OINTMENT 5GM contains Aciclovir, which works by killing and stopping the growth of the herpes simplex virus on the cornea. Thereby treats eye/ocular herpes and herpes simplex keratitis

OCUVIR OINTMENT 5GM is for ophthalmic (for the eye) use only. Common side effects of OCUVIR OINTMENT 5GM include eye irritation, burning or a stinging sensation at the application site, temporary blurred vision, sensitivity to the light, swollen and runny eyes, inflammation of the eyelids, and foreign body sensation. These side effects may not occur in every patient using OCUVIR OINTMENT 5GM and gradually resolve over time if they occur. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are allergic to any medications. Pregnant and breastfeeding women should consult their doctor before starting OCUVIR OINTMENT 5GM. OCUVIR OINTMENT 5GM may cause temporary blurred vision; hence drive only when you are alert and have clear vision. Avoid contact of the tip of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. OCUVIR OINTMENT 5GM should be used in children only when advised by a doctor. 

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Composition

ACICLOVIR-3%W/W

Manufacturer/Marketer

Fdc Limited

Consume Type

OPHTHALMIC

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of OCUVIR OINTMENT 5GM

Eye/ocular herpes and herpes simplex keratitis.

Medicinal Benefits

OCUVIR OINTMENT 5GM treats viral infection of the eye caused by the herpes simplex virus. It consists of Aciclovir, an antiviral drug that works by killing and stopping the growth of the herpes simplex virus on the cornea.

Side Effects of OCUVIR OINTMENT 5GM

  • Eye irritation
  • Sensitivity to the light
  • Swollen and runny eyes
  • Inflammation of the eyelids
  • Foreign body sensation
  • Stinging/burning sensation
  • Temporary blurred vision 

Directions for Use

Eye ointment: Wash your hands thoroughly before applying the eye ointment to your eye to avoid contamination. Please do not touch the ointment tube tip or let it touch your eye or any other surface. Tilt your head back, look upward and create a pouch by pulling your lower eyelid down. Squeeze the tube gently and place a 1cm ribbon of ointment into the lower conjunctival sac. Close your eye and roll the eyeball to ease the spreading of medication. Do not try to blink and avoid rubbing the eye. After using, wipe the tip of the tube with a clean tissue and close the cap tightly. Repeat at regular intervals as suggested by your doctor.Eye drops: Tilt your head back and pull your lower eyelid downwards and outwards. Gently squeeze the dropper and instil the eye drops in the eye/eyes. Blink a few times to spread the medication inside your eye.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you are allergic to any of the components in OCUVIR OINTMENT 5GM. Avoid touching the tip of the dispensing container with bare hands or taking it closer to the eyelids to prevent contamination. If you wear contact lenses, remove them while administering the medicine into the eye. It is advised to check with your doctor before using OCUVIR OINTMENT 5GM if you are pregnant or breastfeeding. Avoid driving or operating machines until you have clear vision since OCUVIR OINTMENT 5GM may cause temporary blurred vision.

Therapeutic Class

ANTIVIRALS

Drug-Drug Interactions

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AciclovirCidofovir
Critical
AciclovirAmphotericin b
Severe

Drug-Drug Interactions

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AciclovirCidofovir
Critical
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Co-administration of Cidofovir with Acyclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Ocuvir Eye Ointment 5 gm with Cidofovir is not recommended, please consult your doctor before taking it. You should consult a doctor if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, and palpitations. Do not stop using any medications without talking to a doctor.
AciclovirAmphotericin b
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Coadministration of Ocuvir Eye Ointment 5 gm with Amphotericin B can increase the risk or severity of kidney disorder.

How to manage the interaction:
Taking Ocuvir Eye Ointment 5 gm with Amphotericin b together can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you experience irregular urination, muscle ache, shortness if breath, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTenofovir alafenamide
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Coadministration of Ocuvir Eye Ointment 5 gm with Tenofovir alafenamide may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Ocuvir Eye Ointment 5 gm with tenofovir alafenamide can result in an interaction. However, if the benefits outweigh the risks, your doctor will prescribe them. Contact a doctor immediately if you experience symptoms such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medication without consulting your doctor.
AciclovirEverolimus
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Coadministration of Ocuvir Eye Ointment 5 gm with Everolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Ocuvir Eye Ointment 5 gm with Everolimus together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, breathing difficulty, muscle pains, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTenofovir disoproxil
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Coadministration of Ocuvir Eye Ointment 5 gm with Tenofovir Disoproxil may increase the risk or severity of kidney disorder.

How to manage the interaction:
Coadministration of Ocuvir Eye Ointment 5 gm with Tenofovir disoproxil can result in an interaction, it can be taken when your doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AciclovirMetrizamide
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Coadministration of Metrizamide in contrast with Ocuvir Eye Ointment 5 gm may increase the risk or severity of kidney disorder.

How to manage the interaction:
Before undergoing any imaging procedure, let your doctor know you are on Ocuvir Eye Ointment 5 gm treatment. Look out for signs such as vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, or weakness. Consult the doctor immediately.
AciclovirSirolimus
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Coadministration of Ocuvir Eye Ointment 5 gm with Sirolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Ocuvir Eye Ointment 5 gm with Sirolimus can result in an interaction, it can be taken if your doctor has advised it. However, if you experience vomiting, a decrease in hunger, irregular urine, weight gain or loss, swelling, difficulty breathing, muscle pain, or weakness, consult a doctor.
AciclovirTizanidine
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Concomitant use of Ocuvir Eye Ointment 5 gm with Tizanidine can increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Ocuvir Eye Ointment 5 gm with Tizanidine can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, excessive sweating, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTacrolimus
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Co-administration of Ocuvir Eye Ointment 5 gm with tacrolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Coadministration of Ocuvir Eye Ointment 5 gm with Tacrolimus can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without first consulting a doctor.
AciclovirIodamide
Severe
How does the drug interact with Ocuvir Eye Ointment 5 gm:
Coadministration of Iodamide contrast with Ocuvir Eye Ointment 5 gm may increase the risk or severity of kidney injury.

How to manage the interaction:
Before undergoing any imaging procedure let your doctor know you are on Ocuvir Eye Ointment 5 gm treatment.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ACYCLOVIR-3%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
ACYCLOVIR-3%W/WVolume depletion
Moderate

Drug-Diseases Interactions

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ACYCLOVIR-3%W/WOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Ocuvir Eye Ointment 5 gm:
Acyclovir should be used with caution to patients who have impaired kidney function. In patients with moderate to severe renal impairment, dosage modifications are advised.

How to manage the interaction:
The use of Ocuvir Eye Ointment 5 gm in kidney disease patients is not advised as it may increase the severity of kidney disease. Your doctor may adjust the dosing according to the severity of your kidney disease.
ACYCLOVIR-3%W/WVolume depletion
Moderate
How does the disease interact with Ocuvir Eye Ointment 5 gm:
Patients who are dehydrated may be more susceptible to nephrotoxicity from using acyclovir. Acyclovir should be infused intravenously over the course of an hour, along with appropriate hydration.

How to manage the interaction:
Ocuvir Eye Ointment 5 gm is excreted through the kidneys, dehydration may cause damage to kidney functions. Ocuvir Eye Ointment 5 gm infusion over an hour is recommended in dehydrated patients. Urine output should be monitored.
ACYCLOVIR-3%W/WCare involving dialysis
Moderate
How does the disease interact with Ocuvir Eye Ointment 5 gm:
Hemodialysis effectively removes acyclovir from the body. Following 6 hours of dialysis, it has been demonstrated that plasma levels of acyclovir decrease by 60%. After hemodialysis, acyclovir should be administered. If not, a second dosage might be administered following each hemodialysis session.

How to manage the interaction:
Patients undergoing hemodialysis should be given Ocuvir Eye Ointment 5 gm after completing hemodialysis as hemodialysis removes 60% of Ocuvir Eye Ointment 5 gm from the body.

Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
  • If you wear contact lenses: Clean and replace contact lenses more often. Never share contact lenses. Always wash your hands before inserting and removing the contact lens. 
  • Avoid staring at the digital screens for longer durations. Rest your eyes every 20 minutes.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Eye/Ocular herpes is an eye infection caused by the herpes simplex virus. Symptoms include eye pain, inflammation, sensitivity to light, blurry vision, redness of the eye, and tearing of the cornea surface. If the infection is severe and spreads to the deeper middle layers of the cornea, it may lead to vision loss and blindness. Treatment involves antiviral medicines and steroids. 

Herpes simplex keratitis is an eye infection caused when the herpes simplex virus affects the cornea (clear front surface of the eye). Symptoms include eye pain, tearing, redness, foreign body sensation, and sensitivity to light. 

OCUVIR OINTMENT 5GM Substitute

Substitutes safety advice
  • Optiviral Eye Ointment 5 gm

    11.70per tablet
  • Acivir Eye Ointment 5 gm

    10.44per tablet
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