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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

CEFADROXIL-250MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Odoxil 250 DT Tablet

Odoxil 250 DT Tablet belongs to the class of cephalosporin antibiotics. It is used to treat upper respiratory tract bacterial infections, the skin and soft tissue, and the urinary system. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

Odoxil 250 DT Tablet contains cefadroxil, which is a new semisynthetic cephalosporin with a broad antibacterial spectrum and a high chemotherapeutic potential when administered orally. It kills the bacteria by inhibiting cell wall synthesis, leading to cell death. Thereby it treats bacterial infections.

Use Odoxil 250 DT Tablet as suggested by the doctor. Your doctor will advise the dose and duration based on the severity of your infection. Like all medicines, Odoxil 250 DT Tablet also causes side effects, although not everybody gets them. Common side effects of Odoxil 250 DT Tablet include diarrhoea, nausea, vomiting, sore tongue, abdominal pain, dyspepsia (indigestion), skin rash, and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Before starting Odoxil 250 DT Tablet , please inform your doctor if you have any allergy to any antibiotic or kidney or liver problems. Do not take the Odoxil 250 DT Tablet on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking the Odoxil 250 DT Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Odoxil 250 DT Tablet as it may cause increased dizziness.

Uses of Odoxil 250 DT Tablet

Bacterial infections

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.Dry syrup: Check the label for directions before use. Mix the content in the prescribed amount of water, mix well and drink as directed by the physician.

Medicinal Benefits

Odoxil 250 DT Tablet belongs to the class of cephalosporin antibiotics. It reduces the infection by inhibiting bacterial growth. It kills the bacteria by disrupting the formation of the cell wall. It irreversibly binds to the proteins in the bacteria that are essential for the formation of the cell membrane. Thereby it treats bacterial infections. Odoxil 250 DT Tablet is a broad-spectrum antibiotic that is effective against both gram-positive and gram-negative bacteria.

Storage

Keep out of sight and reach of children.
Side effects of Odoxil 250 DT Tablet
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Before taking Odoxil 250 DT Tablet , tell your doctor if you are allergic to cefadroxil, cephalosporin antibiotics, or penicillin. People allergic to penicillin may also experience an allergy to cefadroxil due to cross-sensitivity (sensitivity to one drug may cause sensitivity to another drug if they have a similar chemical structure). You may experience ‘Clostridium difficile associated diarrhoea (CDAD)’ after using Odoxil 250 DT Tablet . So, tell your doctor if you are previously diagnosed with gastrointestinal disease (affecting the stomach or intestine), especially colitis (inflammation of the inner lining of the colon (large intestine)). In addition, tell your doctor if you have a history of kidney disease, as dosage adjustments are necessary.

Drug-Drug Interactions

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CefadroxilCholera, live attenuated
Severe
CefadroxilBCG vaccine
Severe

Drug-Drug Interactions

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CefadroxilCholera, live attenuated
Severe
How does the drug interact with Odoxil 250 DT Tablet:
Co-administration of Odoxil 250 DT Tablet with Cholera, live attenuated may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Odoxil 250 DT Tablet or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefadroxilBCG vaccine
Severe
How does the drug interact with Odoxil 250 DT Tablet:
Co-administration of Odoxil 250 DT Tablet with BCG vaccine may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
If you are currently being treated with Odoxil 250 DT Tablet, you should talk to a doctor before receiving BCG. You should not receive the BCG vaccine until after you complete your antibiotic therapy to ensure an adequate response to your treatment. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Odoxil 250 DT Tablet to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium-enriched foods and drinks as it might affect the working of Odoxil 250 DT Tablet .
  • Avoid intake of alcoholic beverages with Odoxil 250 DT Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Odoxil 250 DT Tablet in fighting off infections.

Side Effects of Odoxil 250 DT Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Abdominal pain
  • Severe itching
  • Rash
  • Allergic skin eruptions
  • Hives
  • A swollen, sore tongue

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Drug-Diseases Interactions

verifiedApollotooltip
CEFADROXIL-250MGOther bacterial intestinal infections
Severe
CEFADROXIL-250MGOther disorders of kidney and ureter, not elsewhere classified
Moderate

Drug-Diseases Interactions

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CEFADROXIL-250MGOther bacterial intestinal infections
Severe
How does the disease interact with Odoxil 250 DT Tablet:
Nearly all antibacterial medications have been associated with Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis, which can range in severity from mild diarrhoea to deadly colitis. Lincomycin and clindamycin are typically responsible.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFADROXIL-250MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Odoxil 250 DT Tablet:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in certain situations, as metabolites as well. In individuals with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise and their half-lives may be prolonged. According to the particular product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during extended and/or high-dose therapy since these medicines have occasionally been linked to nephrotoxicity and changes in renal function.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised.

FAQs

Odoxil 250 DT Tablet is used to treat bacterial infections. It reduces the infection by inhibiting bacterial growth. It disrupts the formation of the cell membrane by interfering with protein synthesis, leading to cell death.

Odoxil 250 DT Tablet may disrupt the natural flora present in the intestine leading to ‘Clostridium difficile associated diarrhea'. Take probiotics to restore the gut bacteria after completing the course of antibiotics. Consult a doctor if you have watery or bloody stools.

People allergic to penicillin should not take Odoxil 250 DT Tablet as they may develop cross-sensitivity (sensitivity to drugs that has similar structures). Odoxil 250 DT Tablet contains cefadroxil which has a similar structure to that of penicillin.

Complete the course of therapy as prescribed by your doctor. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics.

Overdose of Odoxil 250 DT Tablet may lead to nausea, hallucinations (seeing or hearing things that are unreal), hyperreflexia (overactive reflexes), extrapyramidal symptoms (involuntary muscle movements), confusion, and a decrease in renal function. Consult a doctor immediately if you accidentally overdose on medicine.

Odoxil 250 DT Tablet does not treat a viral infection like the flu or a common cold. So if you are feeling under the weather, it is best to consult the doctor to know if you need Odoxil 250 DT Tablet for your condition.

Drug-Drug Interactions Checker List

  • TYPHOID VACCINE LIVE
  • CHOLERA VACCINE LIVE
  • BCG VACCINE

Special Advise

  • Your doctor may take blood samples to monitor electrolyte levels in the body. This helps determine the renal (kidney) function as Odoxil 250 DT Tablet may cause renal toxicity. 

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

Have a query?

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Alcohol

Caution

Intake of alcohol while taking Odoxil 250 DT Tablet may increase the risk of side effects.

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Pregnancy

Caution

Odoxil 250 DT Tablet is a category B medicine. It should be used in pregnant women only when required and prescribed by your doctor.

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Breast Feeding

Caution

Odoxil 250 DT Tablet may be excreted in breast milk in low amounts. So, it should be used with caution in breastfeeding mothers.

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Driving

Safe if prescribed

Odoxil 250 DT Tablet should not affect your ability to drive or use machines.

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Liver

Caution

Odoxil 250 DT Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Odoxil 250 DT Tablet dose may have to be adjusted by your doctor.

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Kidney

Caution

Odoxil 250 DT Tablet should be used in patients with kidney diseases with extreme caution as Odoxil 250 DT Tablet may cause renal toxicity. Dose adjustments are necessary.

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Children

Caution

Odoxil 250 DT Tablet should be given to children only if prescribed by a doctor. The dose and duration may vary depending upon the age and severity of the infection.

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