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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Ofact-MZ Paed Suspension 30 ml

Ofact-MZ Paed Suspension 30 ml is an antidiarrheal medicine used to treat diarrhea in children. Diarrhea is defined as loose, watery and frequent bowel movements. This can be acute (temporary) or chronic (long-lasting). Most times, diarrhoea can occur due to various types of bacteria.

Ofact-MZ Paed Suspension 30 ml is a combination medicine containing Ofloxacin (quinolone antibiotic), Metronidazole (antimicrobials), and Simethicone (digestive enzyme). Ofloxacin inhibits bacterial DNA replication by attaching to an enzyme known as DNA gyrase. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It inhibits the protein synthesis interacting with DNA. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping).

Ofact-MZ Paed Suspension 30 ml may cause certain side effects, such as vomiting, diarrhea, nausea, bloating, headache, and stomach pain. These side effects do not require medical attention and gradually resolve over time. However, if these side effects persist or bother your child, please consult your pediatrician. Ofact-MZ Paed Suspension 30 ml should be given as advised by your child's doctor. Do not give your child more than the prescribed dose of Ofact-MZ Paed Suspension 30 ml. Ofact-MZ Paed Suspension 30 ml can be given with or without food. The dose of the medicine will be decided by your pediatrician, depending upon the severity of the infection.

Ofact-MZ Paed Suspension 30 ml is intended for pediatric use only. Avoid giving Ofact-MZ Paed Suspension 30 ml to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition and ongoing medications, including OTC drugs and vitamin supplements, to rule out any possible side effects/interactions. Let your child's doctor know if your child has lung disease, muscle weakness, liver and kidney disease before giving Ofact-MZ Paed Suspension 30 ml to the child.

Uses of Ofact-MZ Paed Suspension 30 ml

Diarrhoea

Directions for Use

Shake the container well before each use. Measure the required amount of this medicine into the measuring cup and administer it to your child. It is advised to measure the quantity accurately with the help of a syringe or measuring spoon containing markings.

Medicinal Benefits

$contains Ofloxacin (quinolone antibiotic), Metronidazole (antimicrobials), and Simethicone (digestive enzyme). Ofloxacin inhibits bacterial DNA replication by attaching to an enzyme known as DNA gyrase. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It inhibits the protein synthesis interacting with DNA. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping). Thus Ofact-MZ Paed Suspension 30 ml helps treat diarrhoea and reduce symptoms of flatulence and stomach discomfort.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ofact-MZ Paed Suspension 30 ml

  • Nausea
  • Diarrhea
  • Stomach upset
  • Bloating
  • Vomiting

Drug Warnings

Avoid giving Ofact-MZ Paed Suspension 30 ml to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, let your paediatrician know if your child has lung disease, muscle weakness, liver, and kidney disease. Dairy products should be avoided along with Ofact-MZ Paed Suspension 30 ml. Inform your paediatrician if your child is taking any iron or zinc supplements or antacids. Do not stop giving this medicine even if your child feels better. Complete the full course as prescribed.

Drug-Drug Interactions

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OfloxacinMesoridazine
Critical
OfloxacinThioridazine
Critical

Drug-Drug Interactions

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OfloxacinMesoridazine
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Using Mesoridazine together with Ofact-MZ Paed Suspension 30 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Ofact-MZ Paed Suspension 30 ml is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinThioridazine
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Coadministration of Ofact-MZ Paed Suspension 30 ml with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinPimozide
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Coadministration of Ofact-MZ Paed Suspension 30 ml with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Coadministration of Ofact-MZ Paed Suspension 30 ml with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinCisapride
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Coadministration of Ofact-MZ Paed Suspension 30 ml with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.
OfloxacinSotalol
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Coadministration of Ofact-MZ Paed Suspension 30 ml with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.
OfloxacinAmiodarone
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
The combination of Amiodarone and Ofact-MZ Paed Suspension 30 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Ofact-MZ Paed Suspension 30 ml interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Using halofantrine together with Ofact-MZ Paed Suspension 30 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinDisopyramide
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Coadministration of Ofact-MZ Paed Suspension 30 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinDronedarone
Critical
How does the drug interact with Ofact-MZ Paed Suspension 30 ml:
Coadministration of Ofact-MZ Paed Suspension 30 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ofact-MZ Paed Suspension 30 ml with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more fiber-enriched food in your child’s diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth.
  • Fiber foods may help restore healthy gut bacteria after a course of antibiotics.
  • Avoid giving too much calcium, or iron-enriched foods, as it might affect the working of Ofact-MZ Paed Suspension 30 ml. 
  • Make your child drink more fluids to avoid dehydration.
  • Do not make your child drink or eat a lot of caffeine-containing products such as cola or chocolate. Ofact-MZ Paed Suspension 30 ml may increase nervousness, sleeplessness, and anxiety.

Habit Forming

No

Therapeutic Class

ANTIDIARRHEALS

Ofact-MZ Paed Suspension 30 ml Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ALUMINIUM HYDROXIDE
  • MAGNESIUM HYDROXIDE
  • CALCIUM CARBONATE

Disease/Condition Glossary

Diarrhoea: Diarrhoea is defined as the occurrence of loose and watery stools due to frequent bowel movements in the stomach. This can be acute (temporary- lasts for a few days) or chronic (long-lasting- lasts for a few weeks). Diarrhoea can lead to the loss of water along with salts, electrolytes, and minerals from the body. This can occur due to various reasons such as food intolerance, food allergy, adverse reaction to a medication, or infections caused by microorganisms. Symptoms include nausea, abdominal pain, cramps, bloating, dehydration, watery loose stools, and frequent urge to evacuate the bowels.

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