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About Olmefast CH 40mg/5mg/12.5mg Tablet

Olmefast CH 40mg/5mg/12.5mg Tablet belongs to a class of medicines called antihypertensives used to treat hypertension (high blood pressure) and reduce the risk of heart attack or stroke in adults. Hypertension is a condition in which the force of blood against the walls of the artery is very high. It will be an addition to the workload of the heart and arteries.

Olmefast CH 40mg/5mg/12.5mg Tablet is a combination of three drugs, namely: Amlodipine (calcium channel blocker), Chlorthalidone (diuretic), and Olmesartan medoxomil (angiotensin II receptor blocker). Amlodipine is a calcium channel blocker that works by acting on muscle cells in the artery walls and relaxes muscle cells. Thereby, it relaxes and widens arteries (blood vessels) and improves the blood flow and oxygen supply to the heart. Chlorthalidone belongs to the class of diuretics (water tablets) that works by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Olmesartan medoxomil works by blocking the action of a hormone called angiotensin II in the body that causes the narrowing of blood vessels leading to high blood pressure. Thereby, Olmefast CH 40mg/5mg/12.5mg Tablet widens and relaxes blood vessels. Thus, it lowers high blood pressure.

Take Olmefast CH 40mg/5mg/12.5mg Tablet as prescribed by your doctor. You are advised to take Olmefast CH 40mg/5mg/12.5mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, headache, swelling of ankles, feet, hands, arms, or legs, low or high blood pressure, stomach upset, or tiredness. Most of these side effects of Olmefast CH 40mg/5mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Olmefast CH 40mg/5mg/12.5mg Tablet or any other medicines, please tell your doctor. Olmefast CH 40mg/5mg/12.5mg Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Olmefast CH 40mg/5mg/12.5mg Tablet and consult a doctor. Drive only if you are alert as Olmefast CH 40mg/5mg/12.5mg Tablet may cause dizziness or drowsiness. You are recommended to avoid alcohol consumption with Olmefast CH 40mg/5mg/12.5mg Tablet as it may increase the risk of low blood pressure.

Uses of Olmefast CH 40mg/5mg/12.5mg Tablet

Hypertension (high blood pressure)

Directions for Use

Take Olmefast CH 40mg/5mg/12.5mg Tablet with food to avoid stomach upset or take it as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush or break it.

Medicinal Benefits

Olmefast CH 40mg/5mg/12.5mg Tablet contains Amlodipine, Chlorthalidone and Olmesartan medoxomil used to treat high blood pressure. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Amlodipine and Olmesartan medoxomil relax and widens blood vessels. Thus, Olmefast CH 40mg/5mg/12.5mg Tablet lowers high blood pressure and reduces the risk of stroke, heart attack or other heart problems.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Olmefast CH 40mg/5mg/12.5mg Tablet or any other medicines, please tell your doctor. Olmefast CH 40mg/5mg/12.5mg Tablet is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, avoid taking Olmefast CH 40mg/5mg/12.5mg Tablet and consult a doctor. Avoid taking Olmefast CH 40mg/5mg/12.5mg Tablet if you have low levels of sodium or potassium in blood, gout, kidney stones, Addison’s disease (adrenal gland does not produce sufficient steroids), high blood levels of calcium, severe liver or kidney problems. Drive only if you are alert as Olmefast CH 40mg/5mg/12.5mg Tablet may cause dizziness or drowsiness. You are recommended to avoid alcohol consumption with Olmefast CH 40mg/5mg/12.5mg Tablet as it may increase the risk of low blood pressure.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Olmefast CH 40mg/5mg/12.5mg Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Using Olmefast CH 40mg/5mg/12.5mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Olmefast CH 40mg/5mg/12.5mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Co-administration of Olmefast CH 40mg/5mg/12.5mg Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Olmefast CH 40mg/5mg/12.5mg Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Taking Amiloride with Olmefast CH 40mg/5mg/12.5mg Tablet can elevate potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking amiloride with Olmefast CH 40mg/5mg/12.5mg Tablet may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Coadministration of Olmefast CH 40mg/5mg/12.5mg Tablet with perindopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmefast CH 40mg/5mg/12.5mg Tablet together with perindopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Taking lithium with Olmefast CH 40mg/5mg/12.5mg Tablet may significantly increase the blood levels of lithium .

How to manage the interaction:
Although taking Olmefast CH 40mg/5mg/12.5mg Tablet alongside lithium can lead to interaction, they can be taken if prescribed by a doctor. However, if you develop sleepiness, dizziness, confusion, loose stools, vomiting, muscular weakness, muscle incoordination, a shaking sensation, blurred vision, ringing in the ears, excessive thirst, and/or increased urination, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Olmefast CH 40mg/5mg/12.5mg Tablet when combined with benazepril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmefast CH 40mg/5mg/12.5mg Tablet with benazepril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Using Olmefast CH 40mg/5mg/12.5mg Tablet with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Olmefast CH 40mg/5mg/12.5mg Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Taking ramipril together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking Olmefast CH 40mg/5mg/12.5mg Tablet with ramipril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Olmefast CH 40mg/5mg/12.5mg Tablet:
Taking Olmefast CH 40mg/5mg/12.5mg Tablet with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Olmefast CH 40mg/5mg/12.5mg Tablet with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+CHLORTHALIDONE-12.5MG+OLMESARTAN MEDOXOMIL-40MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+CHLORTHALIDONE-12.5MG+OLMESARTAN MEDOXOMIL-40MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consumption of grapefruit juice with Olmesartan medoxomil and Amlodipine and chlorthalidone may slightly increase plasma concentrations of amlodipine. Avoid consumption of grapefruit juice with Olmesartan medoxomil and Amlodipine and chlorthalidone.

Diet & Lifestyle Advise

  • Minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, and the way you react in certain situations and do activities that you enjoy by making time for yourself.
  • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Olmefast CH 40mg/5mg/12.5mg Tablet Substitute

Substitutes safety advice
  • Triolmesar CH 40 Tablet 15's

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    25.59per tablet
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    by Others

    24.84per tablet
  • Olbet-Trio 40mg Tablet 10's

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    21.65per tablet
  • Triolmesar CH 40 Tablet 10's

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    38.39per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Olmefast CH 40mg/5mg/12.5mg Tablet contains Amlodipine, Chlorthalidone and Olmesartan medoxomil. Chlorthalidone is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels and improves blood flow. Amlodipine and Olmesartan medoxomil relaxes and widens blood vessels. Thus, Olmefast CH 40mg/5mg/12.5mg Tablet lowers high blood pressure and reduces the risk of stroke, heart attack or other heart problems.

Olmefast CH 40mg/5mg/12.5mg Tablet may increase potassium levels in the blood. Therefore, it is recommended to avoid intake of potassium supplements and foods that are rich in potassium such as bananas, sweet potatoes, nuts and noni juice with Olmefast CH 40mg/5mg/12.5mg Tablet as it may result in hyperkalaemia (high levels of potassium in the blood) and cause severe adverse effects such as irregular heartbeat, muscle paralysis and kidney failure. Also, avoid taking Olmefast CH 40mg/5mg/12.5mg Tablet with grapefruit juice as it increases the levels of Olmefast CH 40mg/5mg/12.5mg Tablet in blood.

Olmefast CH 40mg/5mg/12.5mg Tablet may cause dizziness in some patients. Therefore, if you feel dizzy after taking Olmefast CH 40mg/5mg/12.5mg Tablet, avoid driving or operating heavy machinery.

You are not recommended to take simvastatin with Olmefast CH 40mg/5mg/12.5mg Tablet as it may increase the levels of simvastatin in the blood and increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). However, please consult a doctor before taking other medicines with Olmefast CH 40mg/5mg/12.5mg Tablet.

You are not recommended to stop taking Olmefast CH 40mg/5mg/12.5mg Tablet without consulting your doctor even if you find symptomatic relief as it may worsen the condition. Therefore, take Olmefast CH 40mg/5mg/12.5mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while using Olmefast CH 40mg/5mg/12.5mg Tablet, please consult your doctor.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • INDOMETHACIN
  • LITHIUM
  • HEPARIN
  • COLESEVELAM
  • SIMVASTATIN
  • VERAPAMIL
  • DILTIAZEM
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • TACROLIMUS
  • CYCLOSPORINE
  • EVEROLIMUS
  • SIROLIMUS
  • TEMSIROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • DIGOXIN

Special Advise

Monitor your blood pressure regularly and if you notice any fluctuations, please consult a doctor.

Disease/Condition Glossary

Blood pressure is the measurement of the force that the heart uses to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.

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