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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Olmesar A 40 Tablet

Olmesar A 40 Tablet belongs to the 'anti-hypertensive drugs' class used to treat high blood pressure. Hypertension or high blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it leads to heart disease, irregular heartbeat, and other complications.

Olmesar A 40 Tablet contains Olmesartan (angiotensin receptor blocker) and Amlodipine (calcium channel blocker). Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Amlodipine, on the other hand, acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, collectively, both help lower high blood pressure, reducing heart attack or stroke chances. 

You can take Olmesar A 40 Tablet with food or without food with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. In some cases, you may experience headaches, drowsiness, ankle swelling, nausea, dizziness, and low blood pressure. Most of these side effects of Olmesar A 40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. It is advisable to drink plenty of fluids while taking Olmesar A 40 Tablet .

Try not to stop taking Olmesar A 40 Tablet on your own. Inform your doctor, and your dose might be gradually lowered to avoid a rise in blood pressure and increasing the risk of getting heart disease and stroke. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. If you are pregnant or breastfeeding, please tell your doctor, as it is not recommended for use in pregnancy. It should not be given to children less than 12 years of age.  In diabetic patients, it is advised not to take Aliskiren with Olmesar A 40 Tablet as it may cause an increased risk of low blood pressure (hypotension) and change in kidney functions. 

Do not use Olmesar A 40 Tablet if you have low blood pressure (hypotension) or cardiogenic shock (sudden stopping blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to Olmesar A 40 Tablet . Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Grapefruit juice and St. John's wort plant should not be consumed when taking Olmesar A 40 Tablet as it is contraindicated.

Uses of Olmesar A 40 Tablet

Hypertension (high blood pressure)

Directions for Use

Olmesar A 40 Tablet should not be used unless prescribed by a doctor. Always take Olmesar A 40 Tablet as prescribed by your doctor. Your doctor will advise you on how often you take your tablets based on your medical condition. Swallow Olmesar A 40 Tablet with a full glass of water. Usually, the starting dose of Olmesar A 40 Tablet is 5/20 mg once daily, which may be changed by the doctor depending on the patient's response.

Medicinal Benefits

Olmesar A 40 Tablet contains Olmesartan (angiotensin receptor blocker) and Amlodipine (calcium channel blocker). Olmesartan works by blocking the hormone angiotensin, thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently. Amlodipine, on the other hand, acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, both help lower high blood pressure, reducing the chances of heart attack or stroke.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Olmesar A 40 Tablet should not be given to people allergic to Olmesar A 40 Tablet or many of its ingredients. If you have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, or liver disease, are pregnant, or planning to get pregnant and breastfeeding women; do not take Olmesar A 40 Tablet . Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Olmesar A 40 Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Olmesar A 40 Tablet and breastfeeding. Grapefruit juice and St. John's wort plant should not be consumed when taking Olmesar A 40 Tablet as it is contraindicated. Drinking alcohol while using Olmesar A 40 Tablet can cause low blood pressure, so avoid alcoholic beverages.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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How does the drug interact with Olmesar A 40 Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Olmesar A 40 Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Olmesar A 40 Tablet:
Using Olmesar A 40 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Olmesar A 40 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium citrate
Severe
How does the drug interact with Olmesar A 40 Tablet:
Coadministration of Olmesar A 40 Tablet may increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although taking Olmesar A 40 Tablet together with potassium citrate may result in an interaction, they can be taken together if prescribed by your doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Olmesar A 40 Tablet:
Taking lithium with Olmesar A 40 Tablet may significantly increase the blood levels of lithium .

How to manage the interaction:
Although taking Olmesar A 40 Tablet alongside lithium can lead to interaction, they can be taken if prescribed by a doctor. However, if you develop sleepiness, dizziness, confusion, loose stools, vomiting, muscular weakness, muscle incoordination, a shaking sensation, blurred vision, ringing in the ears, excessive thirst, and/or increased urination, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmesar A 40 Tablet:
Taking Olmesar A 40 Tablet with trimethoprim may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesar A 40 Tablet with trimethoprim may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Olmesar A 40 Tablet:
Taking Olmesar A 40 Tablet with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Olmesar A 40 Tablet with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmesar A 40 Tablet:
Coadministration of Olmesar A 40 Tablet with enalapril can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking Olmesar A 40 Tablet together with enalapril may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Olmesar A 40 Tablet:
Coadministration of Olmesar A 40 Tablet with perindopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesar A 40 Tablet together with perindopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmesar A 40 Tablet:
Using Olmesar A 40 Tablet with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Olmesar A 40 Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Olmesar A 40 Tablet:
Olmesar A 40 Tablet when combined with benazepril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olmesar A 40 Tablet with benazepril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+OLMESARTAN-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+OLMESARTAN-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Olmesar A 40 Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Olmesar A 40 Tablet.

Diet & Lifestyle Advise

  • Keep your weight under control with BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help lower your raised blood pressure by about 5 mm Hg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food and drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Persons older than 65 years can take Olmesar A 40 Tablet after consulting with the doctor. However, Olmesar A 40 Tablet is safe to use by elderly patients if prescribed by the doctor.

Olmesar A 40 Tablet is a Pregnancy Category D medicine that can harm the fetus, so when pregnancy is detected, discontinue Olmesar A 40 Tablet with immediate effect.

It is not recommended that diabetic patients take Aliskiren with Olmesar A 40 Tablet because it increases the risk of low blood pressure (hypotension) and changes in kidney functions.

If you have missed a dose of Olmesar A 40 Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Olmesar A 40 Tablet will lead to low blood pressure.

Inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

Olmesar A 40 Tablet can be safely taken as long as your doctor prescribes it. High blood pressure is life-long, and one should not abruptly discontinue it without discussing it with a doctor.

Olmesar A 40 Tablet is restricted in people with known allergies to any of this medicine's components. It should be used with caution in people with liver impairment. It should also be avoided in women's second and third trimesters of their pregnancy.

Yes, Olmesar A 40 Tablet contains amlodipine, known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

It's unlikely that Olmesar A 40 Tablet affects fertility in men or women. However, there's not enough evidence to say for certain. For the best advice, consult your doctor.

High blood pressure during pregnancy is called 'Pregnancy-induced hypertension' (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth, and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.

Drug-Drug Interactions Checker List

  • ALISKIREN
  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • LISINOPRIL
  • BENAZEPRIL
  • IBUPROFEN
  • ASPIRIN

Special Advise

  • When pregnancy is detected, discontinue Olmesar A 40 Tablet as drugs that act directly on the renin-angiotensin system can cause severe injury and even death to the developing fetus (unborn baby).
  • Olmesar A 40 Tablet should be taken at the same time every day for its maximum effects to be seen and for increased compliance.
  • Consumption of Olmesar A 40 Tablet may cause dizziness. Avoid activities like driving while on this medication.
  • A sudden drop in blood pressure may be seen while on this medication, especially when you start taking it, leading to dizziness. Changing your posture at a slower rate might help counter this. 
  • Ankle swelling is sometimes seen as a side effect of Olmesar A 40 Tablet as it contains amlodipine. Consult your doctor if this or other side effects cause trouble or are persistent.

Disease/Condition Glossary

Blood pressure: It is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor. Systolic pressure is the pressure with which the heart pumps blood. On the other hand, diastolic pressure is when your heart is resting between heartbeats. If your blood pressure is 140/90 mm of Hg, the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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