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Written By Sureshvarma D , MPharma
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Whats That

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Synonym :

CYCLOSPORIN

Composition :

CICLOSPORIN-100MG

Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Oncyclo 100 Softgel Capsule

Oncyclo 100 Softgel Capsule belongs to the class of medicine called 'immunosuppressant' that helps to reduce the pain/inflammation in rheumatoid arthritis conditions and is also used to treat severe psoriasis. Besides this, it also prevents organ rejection after a kidney, heart, or liver transplant. Rheumatoid arthritis is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Psoriasis is a long-lasting, inflammatory skin illness. 

Oncyclo 100 Softgel Capsule contains 'cyclosporine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Oncyclo 100 Softgel Capsule helps stop your body from rejecting a new organ by suppressing your immune system. 

You are advised to take Oncyclo 100 Softgel Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience headaches, vomiting, nausea, high blood pressure, increased growth of hair, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Oncyclo 100 Softgel Capsule for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Before taking Oncyclo 100 Softgel Capsule inform your doctor if you have any allergies, kidney disease, uncontrolled high blood pressure, and any type of cancer. Oncyclo 100 Softgel Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of Oncyclo 100 Softgel Capsule

Rheumatoid arthritis, Immunosuppressant therapy after organ (liver, kidney, and heart) transplant, and psoriasis (a skin disease that causes itchy and dry patches).

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Solution/Syrup/Suspension/Drops: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Oncyclo 100 Softgel Capsule belongs to the class of medicine called 'immunosuppressant' that helps to reduce the pain/inflammation in rheumatoid arthritis conditions and is also used to treat severe psoriasis. Besides this, it also prevents organ rejection after a kidney, heart, or liver transplant. Oncyclo 100 Softgel Capsule contains 'cyclosporine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Oncyclo 100 Softgel Capsule helps stop your body from rejecting a new organ by suppressing your immune system. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oncyclo 100 Softgel Capsule

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Increased growth of hair
  • Loss of appetite (feeling unwell and having an upset stomach)
  • Kidney disease
  • Diarrhoea

Drug Warnings

Do not take Oncyclo 100 Softgel Capsule if you are allergic to any immunosuppressant medicines or Cyclosporine. Let your doctor know if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Oncyclo 100 Softgel Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Oncyclo 100 Softgel Capsule inform your doctor if you have any type of cancer. Oncyclo 100 Softgel Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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CiclosporinBaricitinib
Critical
CiclosporinCidofovir
Critical

Drug-Drug Interactions

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CiclosporinBaricitinib
Critical
How does the drug interact with Oncyclo 100 Softgel Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Oncyclo 100 Softgel Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Oncyclo 100 Softgel Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Oncyclo 100 Softgel Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Oncyclo 100 Softgel Capsule:
Coadministration of pitavastatin with Oncyclo 100 Softgel Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Oncyclo 100 Softgel Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinSimvastatin
Critical
How does the drug interact with Oncyclo 100 Softgel Capsule:
Combining Oncyclo 100 Softgel Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Oncyclo 100 Softgel Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Oncyclo 100 Softgel Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Oncyclo 100 Softgel Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinEdoxaban
Severe
How does the drug interact with Oncyclo 100 Softgel Capsule:
Taking edoxaban and Oncyclo 100 Softgel Capsule can significantly increase the blood levels of edoxaban.

How to manage the interaction:
Taking Oncyclo 100 Softgel Capsule with edoxaban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, bruising, blood in stools or urine, dizziness, severe headache, weakness, or vomiting contact a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinRitonavir
Severe
How does the drug interact with Oncyclo 100 Softgel Capsule:
Taking Oncyclo 100 Softgel Capsule with ritonavir may significantly increases the blood levels of Oncyclo 100 Softgel Capsule.

How to manage the interaction:
Taking ritonavir with Oncyclo 100 Softgel Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loose stools, abdominal pain, dizziness, weakness, headache, fits, shaking, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
CiclosporinTenofovir alafenamide
Severe
How does the drug interact with Oncyclo 100 Softgel Capsule:
Co-administration of tenofovir alafenamide with Oncyclo 100 Softgel Capsule may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction, tenofovir alafenamide can be taken with Oncyclo 100 Softgel Capsule if prescribed by the doctor. However, consult the doctor if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
CiclosporinHydroxychloroquine
Severe
How does the drug interact with Oncyclo 100 Softgel Capsule:
Taking cyclosporine and hydroxychloroquine can increases the blood levels of ciclosporine.

How to manage the interaction:
Co-administration of cyclosporine and hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CiclosporinSulfamethizole
Severe
How does the drug interact with Oncyclo 100 Softgel Capsule:
Coadministration of sulfamethizole with Oncyclo 100 Softgel Capsule may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between sulfamethizole and Oncyclo 100 Softgel Capsule, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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CICLOSPORIN-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CICLOSPORIN-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Oncyclo 100 Softgel Capsule can increase the effects of Oncyclo 100 Softgel Capsule. Avoid consuming grapefruit and grapefruit juice while taking Oncyclo 100 Softgel Capsule.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Oncyclo 100 Softgel Capsule Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Oncyclo 100 Softgel Capsule acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.

If you miss a dose of Oncyclo 100 Softgel Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.

Diarrhoea might be a side-effect of Oncyclo 100 Softgel Capsule. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, using Oncyclo 100 Softgel Capsule may cause abnormal hair growth, although it does not affect everybody. Consult your doctor if you have any concerns.

Oncyclo 100 Softgel Capsule is known to decrease the immune system. As a result, it increases your risk of developing cancers, especially of the skin. You should reduce your contact with sunlight and UV light by wearing suitable protective clothing. Sunscreen should be used regularly.

Drug-Drug Interactions Checker List

  • TACROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • ALISKIREN
  • ATORVASTATIN
  • PITAVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • VORICONAZOLE
  • ITRACONAZOLE
  • DILTIAZEM
  • VERAPAMIL
  • DANAZOL
  • ALLOPURINOL
  • COLCHICINE
  • TELAPREVIR

Special Advise

  • Use sunscreen while taking Oncyclo 100 Softgel Capsule, as it can make your skin more sensitive to sunlight and may cause skin cancer.
  • Long-term use of Oncyclo 100 Softgel Capsule may increase your risk of developing cancers like blood cancer, skin cancer, and immune system cancer (lymphoma). 

Disease/Condition Glossary

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Organ (kidney, heart, or liver) transplant rejection: When you get a new organ transplanted into your body, your body recognizes it as a foreign element and tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs like cyclosporine are given to such patients to suppress their immune system to prevent an attack on a newly transplanted organ. The goal is to adjust immunosuppressants to prevent rejection and minimize any side effects of the drugs.

Psoriasis: It is a long-lasting, inflammatory skin illness. It is not infectious but has a tendency to run in families. It causes itchy and red patches on the skin.

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