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Opdyta 40 mg Injection 1's is an anti-cancer medicine used in the treatment of Melanoma in combination with ipilimumab and other cancers in adults. Melanoma is a severe form of skin cancer that spreads primary melanoma cells to distant organs such as lymph nodes, lungs, liver, brain, and bones. This medicine is used in treating advanced renal cell carcinoma, hepatocellular carcinoma, colorectal cancer, metastatic non-small cell lung cancer, metastatic melanoma, gastric cancer, classical Hodgkin’s disease, urothelial carcinoma, malignant pleural mesothelioma and head and neck cancer.
Opdyta 40 mg Injection 1's contains Nivolumab, which belongs to the class of monoclonal antibody. It works by inhibiting the action of a programmed death receptor-1 (PD-1), thereby stopping the abnormal growth of cancer cells.
Opdyta 40 mg Injection 1's may cause certain side effects such as diarrhoea, nausea, vomiting, tiredness, itching, rash, headache, fever, shortness of breath, muscle/joint pain, loss of appetite and injection site reactions. Inform your doctor if any of these side effects persist for longer. Opdyta 40 mg Injection 1's will be administered by an oncologist trained in administering anti-cancer agents.
Avoid receiving Opdyta 40 mg Injection 1's and inform your doctor if you are allergic to it or any other components of it. Before taking Opdyta 40 mg Injection 1's, tell your doctor if you have/had liver or kidney disease, autoimmune disorders such as ulcerative colitis or Crohn's disease, a history of organ transplants, received an allogeneic stem cell transplant, or had radiation treatment to the chest. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy. Avoid breastfeeding while taking this Opdyta 40 mg Injection 1's.
Opdyta 40 mg Injection 1's contains Nivolumab, which is used in the treatment of different types of cancers. It works by inhibiting the action of a programmed death receptor-1 (PD-1) that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other body parts.
To treat your condition effectually, continue receiving Opdyta 40 mg Injection 1's for the period that your doctor has prescribed. Opdyta 40 mg Injection 1's may cause severe immune-mediated adverse reactions (IMAR) such as immune-mediated colitis, hepatitis, hepatotoxicity, nephritis, endocrinopathies, pneumonitis, complications of allogeneic Hematopoietic Stem Cell Transplantation (allo HSCT) and dermatologic reactions. It may also cause infusion-related reactions in some patients. Therefore, caution should be exercised if you have/had liver or kidney disease, any history of organ transplant, gastrointestinal disorders, myasthenia gravis, received a stem cell transplant that uses donor stem cells (allogeneic), undergone radiation treatment to the chest and autoimmune disorders such as ulcerative colitis, or Crohn’s disease while receiving Opdyta 40 mg Injection 1's. Discontinue the treatment if any severe infusion reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy are not established.
Drug-Drug Interactions: Opdyta 40 mg Injection 1's may have interaction with immunomodulator drugs (thalidomide), corticosteroids (prednisolone, methylprednisolone, prednisone), etc.
Drug-Food Interactions: Avoid alcohol consumption and smoking.
Dug-Disease Interactions: Tell your doctor if you have liver or kidney disease, heart problems, GI disorders, eye problems, dermatitis, or a weak immune system before starting the treatment.
Renal Cell Carcinoma: It is the most common type of cancer in which cancer/ malignant cells grow uncontrollably in the kidney and form a tumor. Symptoms include red, orange, or pink-coloured urine due to the presence of blood in the urine. Opdyta 40 mg Injection 1's is used in combination with ipilimumab in adult patients who have already taken prior treatment and in combination with cabozantinib in patients who have not taken prior treatment.
Hepatocellular carcinoma: It occurs when the cancer/ malignant cells grow out of control. This infects the liver, destroys the liver cells and affects the ability of the liver to work properly. Symptoms may include abdominal pain, loss of appetite, weight loss, and pale bowel motions. Opdyta 40 mg Injection 1's is used in combination with ipilimumab in adult patients.
Colorectal cancer: It is a condition in which the cancerous/malignant cells grow out of control in the colon or rectum. Symptoms may include diarrhoea, constipation, bloody stools, change in bowel habits, abdominal discomfort, etc.
Metastatic Malignant Melanoma: Melanoma is a type of skin cancer in which the cancer cells grow in melanocytes. It is mainly caused by harmful UV radiation from the sun. Malignant melanoma is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face. Opdyta 40 mg Injection 1's is used in combination with ipilimumab in adults and children above 12 years of age.
Malignant pleural mesothelioma: It is a type of cancer that develops in the mesothelium (a lining that covers the outer surface of organs), mainly caused by exposure to asbestos. Symptoms may include chest pain, shortness of breath, extreme tiredness, persistent cough, loss of appetite, unexplained weight loss, fever and sweating.
Non-Small Cell Lung Cancer (NSCLC): It is the most common form of lung cancer, which occurs when cells that form the lining of the lung start growing uncontrollably. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing. Opdyta 40 mg Injection 1's is used in combination with chemotherapy that contains platinum and another chemotherapy medicine.
Head and neck cancer: It is a type of cancer which causes abnormal growth of cancer cells in the tissues of the neck and head. This cancer generally starts in the cells known as squamous cells, which appear in the lining of the surface of moist mucosa in the head and neck (e.g., inside of the throat, nose, and mouth).
Bladder cancer: It is a cancer that begins in the bladder. It typically affects older adults. The most common symptom is blood in the urine..
Stomach Cancer (Gastric adenocarcinoma): It is a type of cancer that develops from the stomach lining. When the cancer cells spread to other organs of the body, it is called metastatic. This condition can occur mainly due to smoking, a highly processed or salty diet, and severe bacterial infection of H. pylori. Symptoms of stomach cancer include feeling bloated after eating, feeling full after eating small amounts of food, nausea, heartburn or indigestion.
Classical Hodgkin’s Disease: Hodgkin’s disease or lymphoma is a blood cancer of a certain type of cells called WBCs, specifically lymphocytes. Lymphocytes normally help control infection and maintain the body's normal immunity. However, in a cancerous state, there is an abnormal multiplication of these blood cells, causing many problems such as fatigue, fever, loss of appetite, itching, night sweats and lymph node swelling.
About Opdyta 40 mg Injection 1's
Opdyta 40 mg Injection 1's is an anti-cancer medicine used in the treatment of Melanoma in combination with ipilimumab and other cancers in adults. Melanoma is a severe form of skin cancer that spreads primary melanoma cells to distant organs such as lymph nodes, lungs, liver, brain, and bones. This medicine is used in treating advanced renal cell carcinoma, hepatocellular carcinoma, colorectal cancer, metastatic non-small cell lung cancer, metastatic melanoma, gastric cancer, classical Hodgkin’s disease, urothelial carcinoma, malignant pleural mesothelioma and head and neck cancer.
Opdyta 40 mg Injection 1's contains Nivolumab, which belongs to the class of monoclonal antibody. It works by inhibiting the action of a programmed death receptor-1 (PD-1), thereby stopping the abnormal growth of cancer cells.
Opdyta 40 mg Injection 1's may cause certain side effects such as diarrhoea, nausea, vomiting, tiredness, itching, rash, headache, fever, shortness of breath, muscle/joint pain, loss of appetite and injection site reactions. Inform your doctor if any of these side effects persist for longer. Opdyta 40 mg Injection 1's will be administered by an oncologist trained in administering anti-cancer agents.
Avoid receiving Opdyta 40 mg Injection 1's and inform your doctor if you are allergic to it or any other components of it. Before taking Opdyta 40 mg Injection 1's, tell your doctor if you have/had liver or kidney disease, autoimmune disorders such as ulcerative colitis or Crohn's disease, a history of organ transplants, received an allogeneic stem cell transplant, or had radiation treatment to the chest. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy. Avoid breastfeeding while taking this Opdyta 40 mg Injection 1's.
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Uses of Opdyta 40 mg Injection 1's
Medicinal Benefits
Opdyta 40 mg Injection 1's contains Nivolumab, which is used in the treatment of different types of cancers. It works by inhibiting the action of a programmed death receptor-1 (PD-1) that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other body parts.
Side Effects of Opdyta 40 mg Injection 1's
Directions for Use
Storage
Drug Warnings
To treat your condition effectually, continue receiving Opdyta 40 mg Injection 1's for the period that your doctor has prescribed. Opdyta 40 mg Injection 1's may cause severe immune-mediated adverse reactions (IMAR) such as immune-mediated colitis, hepatitis, hepatotoxicity, nephritis, endocrinopathies, pneumonitis, complications of allogeneic Hematopoietic Stem Cell Transplantation (allo HSCT) and dermatologic reactions. It may also cause infusion-related reactions in some patients. Therefore, caution should be exercised if you have/had liver or kidney disease, any history of organ transplant, gastrointestinal disorders, myasthenia gravis, received a stem cell transplant that uses donor stem cells (allogeneic), undergone radiation treatment to the chest and autoimmune disorders such as ulcerative colitis, or Crohn’s disease while receiving Opdyta 40 mg Injection 1's. Discontinue the treatment if any severe infusion reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy are not established.
Therapeutic Class
Drug-Drug Interactions Checker List
Diet & Lifestyle Advise
Habit Forming
Special Advise
Disease/Condition Glossary
Renal Cell Carcinoma: It is the most common type of cancer in which cancer/ malignant cells grow uncontrollably in the kidney and form a tumor. Symptoms include red, orange, or pink-coloured urine due to the presence of blood in the urine. Opdyta 40 mg Injection 1's is used in combination with ipilimumab in adult patients who have already taken prior treatment and in combination with cabozantinib in patients who have not taken prior treatment.
Hepatocellular carcinoma: It occurs when the cancer/ malignant cells grow out of control. This infects the liver, destroys the liver cells and affects the ability of the liver to work properly. Symptoms may include abdominal pain, loss of appetite, weight loss, and pale bowel motions. Opdyta 40 mg Injection 1's is used in combination with ipilimumab in adult patients.
Colorectal cancer: It is a condition in which the cancerous/malignant cells grow out of control in the colon or rectum. Symptoms may include diarrhoea, constipation, bloody stools, change in bowel habits, abdominal discomfort, etc.
Metastatic Malignant Melanoma: Melanoma is a type of skin cancer in which the cancer cells grow in melanocytes. It is mainly caused by harmful UV radiation from the sun. Malignant melanoma is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face. Opdyta 40 mg Injection 1's is used in combination with ipilimumab in adults and children above 12 years of age.
Malignant pleural mesothelioma: It is a type of cancer that develops in the mesothelium (a lining that covers the outer surface of organs), mainly caused by exposure to asbestos. Symptoms may include chest pain, shortness of breath, extreme tiredness, persistent cough, loss of appetite, unexplained weight loss, fever and sweating.
Non-Small Cell Lung Cancer (NSCLC): It is the most common form of lung cancer, which occurs when cells that form the lining of the lung start growing uncontrollably. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing. Opdyta 40 mg Injection 1's is used in combination with chemotherapy that contains platinum and another chemotherapy medicine.
Head and neck cancer: It is a type of cancer which causes abnormal growth of cancer cells in the tissues of the neck and head. This cancer generally starts in the cells known as squamous cells, which appear in the lining of the surface of moist mucosa in the head and neck (e.g., inside of the throat, nose, and mouth).
Bladder cancer: It is a cancer that begins in the bladder. It typically affects older adults. The most common symptom is blood in the urine..
Stomach Cancer (Gastric adenocarcinoma): It is a type of cancer that develops from the stomach lining. When the cancer cells spread to other organs of the body, it is called metastatic. This condition can occur mainly due to smoking, a highly processed or salty diet, and severe bacterial infection of H. pylori. Symptoms of stomach cancer include feeling bloated after eating, feeling full after eating small amounts of food, nausea, heartburn or indigestion.
Classical Hodgkin’s Disease: Hodgkin’s disease or lymphoma is a blood cancer of a certain type of cells called WBCs, specifically lymphocytes. Lymphocytes normally help control infection and maintain the body's normal immunity. However, in a cancerous state, there is an abnormal multiplication of these blood cells, causing many problems such as fatigue, fever, loss of appetite, itching, night sweats and lymph node swelling.