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About Ostishine Nasal Spray 6 ml
Ostishine Nasal Spray 6 ml belongs to groups of medications called hypocalcemic agents, primarily indicated for the treatment of postmenopausal osteoporosis in women more than five years postmenopause when alternative therapies are unsuitable. Post-menopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period.
Ostishine Nasal Spray 6 ml contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus it helps to treat osteoporosis in postmenopausal women.
Use Ostishine Nasal Spray 6 ml as prescribed by the doctor. Ostishine Nasal Spray 6 ml may cause certain side effects such as hypocalcemia, runny nose, nosebleed, sinus pain, application site reactions such as rhinitis (stuffy nose), epistaxis (nose bleeds) and other nasal symptoms, back pain, arthralgia (Joint pain) and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
Ostishine Nasal Spray 6 ml is for intranasal use only, do not inject or take it orally. Before using Ostishine Nasal Spray 6 ml, inform your doctor of all your medical conditions, sensitivities, and all medications you are using. Ostishine Nasal Spray 6 ml is intended for post-menopausal women; therefore, Ostishine Nasal Spray 6 ml should not be recommended for other populations. Avoid drinking alcohol because it affects how the body absorbs calcium and vitamin D, which are essential for good bone formation.
Uses of Ostishine Nasal Spray 6 ml

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Directions for Use
Key Benefits
Ostishine Nasal Spray 6 ml contains Calcitonin, a calcitonin receptor agonist that prevents the loss of bones that happens after menopause and helps to rebuild bones. Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the parathyroid hormone's action, helping regulate the blood’s calcium and phosphate levels. Ostishine Nasal Spray 6 ml works by suppressing the activity of the osteoclasts (cells that break down bone). When the osteoclasts break down bone tissue, the calcium enters the bloodstream. Ostishine Nasal Spray 6 ml lessens the amount of calcium in the blood by preventing the breakdown of bone. Thereby, Ostishine Nasal Spray 6 ml strengthens the bones and minimizes the risk of fractures. Ostishine Nasal Spray 6 ml also seems to decrease the amount of calcium the kidneys can re-absorb, lowering calcium levels further.
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Drug Warnings
Before using Ostishine Nasal Spray 6 ml, Inform your doctor about all your medical conditions, sensitivities, and all medications you are using. Ostishine Nasal Spray 6 ml is intended for post-menopausal women; therefore, Ostishine Nasal Spray 6 ml should not be recommended for other populations. In rare situations, individuals using Ostishine Nasal Spray 6 ml may be affected with anaphylactic shock (a sudden, severe, life-threatening allergic reaction leading to difficulty breathing); if you encounter it, stop using Ostishine Nasal Spray 6 ml and contact your doctor immediately.
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Alcohol
Safe if prescribed
Consuming alcohol is not advisable; it affects how the body absorbs calcium and vitamin D, both of which are essential for good bone formation.
Pregnancy
Consult your doctor
Ostishine Nasal Spray 6 ml is intended for postmenopausal women only. So, it is not recommended for use in pregnancy.
Breast Feeding
Consult your doctor
Ostishine Nasal Spray 6 ml is intended for postmenopausal women only. So, it is not recommended for use in breastfeeding women.
Driving
Safe if prescribed
Ostishine Nasal Spray 6 ml does not impact your ability to drive or operate machinery.
Liver
Consult your doctor
Limited information is available on the use of Ostishine Nasal Spray 6 ml in patients with liver disease. Inform your doctor before receiving the Ostishine Nasal Spray 6 ml if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Consult your doctor
Limited information is available about using Ostishine Nasal Spray 6 ml in patients with liver disease. Inform your doctor before receiving the Ostishine Nasal Spray 6 ml if you have a history of liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Safe if prescribed
Ostishine Nasal Spray 6 ml is intended for postmenopausal women only. So, it is recommended not to use it in children.
Ostishine Nasal Spray 6 ml contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness).
If you have osteoporosis, avoid smoking, or try to quit. Tobacco use disrupts the mechanisms of bone turnover, resulting in reduced bone mass and bone mineral density (BMD), making bones prone to osteoporosis.
Ostishine Nasal Spray 6 ml contains Calcitonin, a hormone that regulates the calcium level in the blood. This hormone helps in bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damages bones become comparatively less; hence the bone damage is halted. Using Ostishine Nasal Spray 6 ml can increase bone formation by activation of the bone-forming cells.
Persons whose age is more than 45 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.
Yes, Ostishine Nasal Spray 6 ml is used together with calcium and vitamin D to treat bone loss in women with postmenopausal osteoporosis who have been postmenopausal for at least five years. Ostishine Nasal Spray 6 ml inhibits the function of osteoclasts (bone breakdown), reducing bone resorption; thus, combining calcium and calcitonin could result in a positive bone balance.
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