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Written By Divya L , PharmaD
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

OLANZAPINE-50MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Oxalitero 50 mg Injection

Oxalitero 50 mg Injection belongs to a group of medicines called 'atypical antipsychotics,' primarily used to treat schizophrenia and manic or mixed episodes of bipolar I disorder. Schizophrenia is a mental condition in which you may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. Bipolar I disorder is a serious brain disorder where you experience extreme mood swings (variance in thinking) and frequent mood and behaviour changes.

Oxalitero 50 mg Injection contains 'Olanzapine' that works by restoring the balance of chemical messengers in the brain and improves thinking mood, and behaviour. Oxalitero 50 mg Injection improves mental clarity and lessens hallucinations. It is used to treat schizophrenia-related agitation and the manic phases of bipolar disorder.

Oxalitero 50 mg Injection will be administered by a health care professional; do not self-administer. Common side effects include drowsiness, dizziness, headache, dry mouth, nausea, vomiting, diarrhoea, constipation, stomach pain, back pain, runny/stuffy nose, cough, increased appetite, weight gain, and redness/pain/swelling at the injection site. These side effects are not common for everyone. If you notice any side effects that are not manageable, please consult your doctor. 

Oxalitero 50 mg Injection is not recommended for treatment in patients with Dementia-Related Psychosis. Inform your doctor beforehand if you have a history of allergic reactions to Olanzapine, Alzheimer's disease, liver or kidney diseases, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, breast cancer, enlarged prostate, and fits before taking this medicine. If you are pregnant, planning to conceive, or breastfeeding, inform your doctor before receiving Oxalitero 50 mg Injection. Avoid consuming alcohol along with Oxalitero 50 mg Injection as it can make you dizzy or drowsy. Do not drive or operate machinery after using Oxalitero 50 mg Injection since it can make you sleepy. Olanzapine is not recommended for children and adolescents below 18 years of age; however, please seek medical advice.

Uses of Oxalitero 50 mg Injection

Schizophrenia and bipolar I disorder.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Oxalitero 50 mg Injection is used to treat manic episodes of bipolar I disorder and agitation in schizophrenia. It contains 'Olanzapine,' which belongs to the class of atypical antipsychotics. It works by restoring the balance of chemical messengers in the brain. It is also known to improve thinking, mood, and behaviour. It helps in clear thinking and relieves psychotic symptoms like hallucinations.

Storage

Store in a cool and dry place away from sunlight
Side effects of Oxalitero 50 mg Injection
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.

Drug Warnings

Oxalitero 50 mg Injection is not recommended for use in patients with Dementia-Related Psychosis. Brief your medical history to the doctor if you have any allergic reactions, liver or kidney diseases, Alzheimer's disease, dementia, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, bowel problems, sleep apnea, low white blood cell count, breast cancer, enlarged prostate, or fits before starting Oxalitero 50 mg Injection. Please inform your doctor if you are pregnant or planning to conceive before starting this medicine. Oxalitero 50 mg Injection is not recommended during breastfeeding. Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness. Avoid driving or operating machinery as Oxalitero 50 mg Injection may decrease your mental alertness, making you feel dizzy or drowsy. Oxalitero 50 mg Injection is not recommended for people below 18 years of age as safety and effectiveness have not been established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Oxalitero 50 mg Injection:
Combining Oxalitero 50 mg Injection with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Oxalitero 50 mg Injection with Ziprasidone is not recommended, please consult your doctor before taking it.
How does the drug interact with Oxalitero 50 mg Injection:
Co-administration of Oxalitero 50 mg Injection with Clozapine can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
Although taking Oxalitero 50 mg Injection and Clozapine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Oxalitero 50 mg Injection:
Combining Infliximab with Oxalitero 50 mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Oxalitero 50 mg Injection with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oxalitero 50 mg Injection:
Using Moxifloxacin together with Oxalitero 50 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Oxalitero 50 mg Injection and Moxifloxacin, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience dizziness, shortness of breath, or heart palpitations (irregular heartbeat). Do not stop using any medications without a doctor's advice.
How does the drug interact with Oxalitero 50 mg Injection:
The combined use of Oxalitero 50 mg Injection and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of oxalipatin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Oxalitero 50 mg Injection:
When Etanercept is used with Oxalitero 50 mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Oxalitero 50 mg Injection and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Oxalitero 50 mg Injection:
Combining Oxalitero 50 mg Injection and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Oxalitero 50 mg Injection and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Oxalitero 50 mg Injection:
Taking Tofacitinib with Oxalitero 50 mg Injection may increase the risk of infection.

How to manage the interaction:
Although taking Oxalitero 50 mg Injection and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
How does the drug interact with Oxalitero 50 mg Injection:
Coadministration of Amiodarone together with Oxalitero 50 mg Injection may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Oxalitero 50 mg Injection interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oxalitero 50 mg Injection:
Combining Cladribine with Oxalitero 50 mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Oxalitero 50 mg Injection and Cladribine, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Oxalitero 50 mg Injection contains Olanzapine, an antipsychotic that balances the chemical messengers in the brain, improving mood, behaviour and thoughts.

Oxalitero 50 mg Injection should be used with caution in the medical history of allergic reactions, liver or kidney diseases, heart problems, Alzheimer's disease, high cholesterol, glaucoma, diabetes, stomach/intestinal problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits. Please let your doctor know if you have any other medical history before starting the treatment with Oxalitero 50 mg Injection.

Oxalitero 50 mg Injection may make you sweat less and can likely cause a heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.

Oxalitero 50 mg Injection may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.

Olanzapine can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. This medicine should be cautiously advised in people with cardiovascular and cerebrovascular diseases. Patients taking Oxalitero 50 mg Injection are advised to regularly monitor their blood pressure levels to avoid any unpleasant events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.

Drug-Drug Interactions Checker List

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  • WARFARIN

Special Advise

  • Let your doctor know that you are taking Oxalitero 50 mg Injection if you are undergoing any medical tests.
  • Weight gain has been noticed in patients who use Olanzapine; hence, regular weight monitoring is recommended.
  • Orthostatic hypotension is also recorded in patients using this medicine. Hence caution is recommended in patients with cardiovascular and cerebrovascular diseases. 
  • Oxalitero 50 mg Injection may affect blood glucose levels; hence it is advised to monitor blood sugar levels regularly while using Oxalitero 50 mg Injection. 
  • Timely monitoring of the cholesterol/triglyceride levels and Prolactin hormone levels is advised for the patient while using this medicine.

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc. Schizophrenia is triggered by physical, genetic, psychological, and environmental factors. Patients suffering from this disease may require lifelong treatment. Treatment involves a combination of medications, psychotherapy and care services.

Bipolar I disorder: It is a serious brain disorder in which a person goes through unusual mood changes (mood swings) and frequent changes in his/her behaviour and thinking. The symptoms may last at least seven days (most of the day, nearly every day), or the manic symptoms are so severe that the person needs immediate hospital care. Treatment involves mood stabilizers, antipsychotics, and sometimes sedative-hypnotics.

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