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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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About Oxerute Cream

Oxerute Cream belongs to the group of medicines called anorectal preparations used to treat anal fissures and haemorrhoids (piles). Haemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause discomfort, pain and bleeding. An anal fissure is a small tear in the mucosa that lines the anus. This causes pain and bleeding during or after a bowel movement. Oxerute Cream relieves pain, inflammation, discomfort and itching associated with piles and anal fissures.
 
Oxerute Cream contains Calcium dobesilate (vasoprotective agent), Hydrocortisone (steroid), Lidocaine (local anaesthetic), Troxerutin (vasoprotective agent), Zinc oxide (antiseptic) and Phenylephrine (decongestant). Calcium dobesilate and Troxerutin promote healing and lower inflammation by decreasing the viscosity of the blood and reducing leakage from the blood vessels. Hydrocortisone helps in reducing itching, redness and swelling due to piles. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreasing the sensation of pain. Phenylephrine decreases irritation and discomfort by shrinking the blood vessels in the affected area. Zinc oxide has an antiseptic and astringent action. Together, Oxerute Cream provides relief from pain and discomfort due to piles and anal fissures.
 
You are advised to use Oxerute Cream for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as burning sensation, irritation, itching and redness at the site of application. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Do not use Oxerute Cream if you had a skin reaction or irritation to any steroid medicine. Consult your doctor before using Oxerute Cream if you are pregnant or breastfeeding. Do not use Oxerute Cream for longer durations unless prescribed by your doctor. If your condition does not improve despite using Oxerute Cream for 2-4 weeks, please consult your doctor. Do not use Oxerute Cream over a large area or use tight-fitting diapers/plastic pants unless directed by your doctor. Inform your doctor about your health condition and medications to rule out any side-effects.

Uses of Oxerute Cream

Piles and anal fissures

Directions for Use

Clean and dry the affected area. Take a pea-sized amount onto the applicator and apply it directly onto the rectal area.

Medicinal Benefits

Oxerute Cream is a combination of six drugs, namely: Calcium dobesilate, Hydrocortisone, Lidocaine, Troxerutin, Zinc oxide and Phenylephrine. Oxerute Cream belongs to the group of medicines called anorectal preparations used to treat anal fissures and haemorrhoids (piles). Calcium dobesilate and Troxerutin are vasoprotective agents that promote healing and lower inflammation by decreasing the viscosity of the blood and reducing leakage from the blood vessels. Hydrocortisone is a steroid which helps in reducing itching, redness and swelling due to piles. Lidocaine is a local anaesthetic that blocks the pain signals from the nerves to the brain, thereby decreasing the sensation of pain. Phenylephrine is a decongestant that decreases irritation and discomfort by shrinking the blood vessels in the affected area. Zinc oxide has an antiseptic and astringent action. Together, Oxerute Cream provides relief from pain, inflammation, discomfort, and itching associated with piles and anal fissures.

Storage

Keep Oxerute Cream out of reach and sight of children.
Side effects of Oxerute Cream 50 gm
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Tell your doctor if you notice any unusual symptoms after taking the medication, such as flat purple, or red spots on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Drink plenty of fluids to stay hydrated, and eat fruits and vegetables or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.
  • Regularly wash your hands with alcohol-based sanitizer or soap and water.
  • Also, avoid sharing personal items like glasses or utensils with other individuals.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Avoid scratching the affected area.
  • Wear loose clothing to reduce irritation.
  • Keep the affected area moisturized with a gentle moisturizer.
  • To alleviate the reaction, remove the irritant by immediately stopping contact and washing the area with mild soap and cool water.
  • Apply a cool, wet compress to reduce inflammation and itching.
  • Consult a doctor if your skin reaction is severe, widespread, or accompanied by swelling, blistering, or breathing difficulties.

Drug Warnings

Do not use Oxerute Cream if you are allergic to any of its contents. Do not exceed the dose and duration prescribed by your doctor. Consult your doctor before using Oxerute Cream if you are pregnant or breastfeeding. Do not use Oxerute Cream for longer durations unless prescribed by your doctor. If your condition does not improve despite using Oxerute Cream for 2-4 weeks, please consult your doctor. Do not use Oxerute Cream over a large area or use tight-fitting diapers/plastic pants unless directed by your doctor. 

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Eat fibre-rich food and drink plenty of fluids. This helps to keep the stools soft.
  • A warm bath helps in easing pain and itching.
  • Keep your bottom dry and clean.
  • Regular exercise is recommended.
  • Avoid or limit alcohol and caffeinated products to prevent constipation.
  • Empty your bowels whenever your body tells you to.
  • Avoid pushing too hard while pooping as it can cause tissue tearing.
  • Include fruits, vegetables and whole wheat grains in your diet.

Side Effects of Oxerute Cream

  • Burning sensation
  • Irritation
  • Itching
  • Redness 

Habit Forming

No

Therapeutic Class

ANORECTAL PREPARATIONS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Oxerute Cream is a combination of six drugs, namely: Calcium dobesilate, Hydrocortisone, Lidocaine, Troxerutin, Zinc oxide, and Phenylephrine. Calcium dobesilate and Troxerutin promote healing and lower inflammation by decreasing the viscosity of the blood and reducing leakage from the blood vessels. Hydrocortisone helps in reducing itching, redness and swelling due to piles. Lidocaine blocks the pain signals from the nerves to the brain, thereby decreasing the sensation of pain. Phenylephrine decreases irritation and discomfort by shrinking the blood vessels in the affected area. Zinc oxide has an antiseptic and astringent action. Together, Oxerute Cream relieves pain and discomfort due to piles and anal fissures.

Oxerute Cream contains a steroid; therefore, it should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using Oxerute Cream for a few weeks, consult your doctor, he/she may prescribe you an alternate medicine.

Continue using Oxerute Cream for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while using Oxerute Cream.

No, Oxerute Cream should not be used on the face or any other body parts. It is intended to treat pain and discomfort associated with piles and anal fissures.

The symptoms of anal fissures and piles are similar. However, an anal fissure is a small tear in the mucosa that lines the anus, whereas piles are inflamed and swollen veins in the rectum and anus that cause discomfort, pain and bleeding.

Oxerute Cream may cause a burning sensation of the skin at the site of application as a temporary side effect. However, if the burning sensation persists or worsens, please consult a doctor.

Disease/Condition Glossary

Piles: Hemorrhoids, also known as piles, are the inflamed and swollen veins in the rectum and anus that cause discomfort, pain, and bleeding. Haemorrhoids can be external or internal. Internal haemorrhoids develop within the rectum and anus, whereas external haemorrhoids develop outside the anus region. Piles cause pain, itching and bleeding. They also cause trouble in sitting. Symptoms include itching, irritation and pain around the anus, swelling near the anus region, painful bowel movements and blood in stools.

Anal fissure: Anal fissure is a small tear in the mucosa that lines the anus. This causes pain and bleeding during or after a bowel movement. Anal fissures generally heal on their own. If the condition lasts for more than 8 weeks, it can be considered chronic. Sometimes surgery may also be needed depending on the condition. Symptoms include tear of skin around the anus region, burning sensation, pain and blood during a bowel movement.

Have a query?

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Alcohol

Caution

It is not known whether Oxerute Cream interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Please consult a doctor if you are pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Oxerute Cream can be used by breastfeeding mothers or not.

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Driving

Safe if prescribed

Oxerute Cream usually does not affect your ability to drive.

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Liver

Caution

Please consult your doctor if you have any concerns regarding the usage of Oxerute Cream in patients with liver impairment.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the usage of Oxerute Cream in patients with kidney impairment.

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Children

Caution

Please consult a doctor regarding the usage of Oxerute Cream in children. Oxerute Cream should be used in children only if prescribed by a doctor.

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