Oxramet 5 mg/500 mg Tablet 14's

Written By Divya L , PharmaD

Reviewed By Sureshvarma D , MPharma

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MRP ₹109.5

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About Oxramet 5/500 mg Tablet

Oxramet 5/500 mg Tablet belongs to the class of 'antidiabetic drugs', primarily used to treat type 2 diabetes mellitus with a proper diet and exercise. Oxramet 5/500 mg Tablet also lowers the risk of heart failure in type 2 diabetic patients with heart diseases. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. Oxramet 5/500 mg Tablet is not indicated for use in type 1 diabetes.

Oxramet 5/500 mg Tablet is composed of two antidiabetic medicines, namely: Metformin and Dapagliflozin. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine.

Take Oxramet 5/500 mg Tablet as advised by your doctor. Some common side effects of Oxramet 5/500 mg Tablet include nausea, vomiting, diarrhoea, headache, weakness, runny nose, genital infection, dizziness, taste changes, and sore throat. Sometimes, Oxramet 5/500 mg Tablet can cause side effects like lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation) and diabetic ketoacidosis (excess production of blood acids (ketones)). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Oxramet 5/500 mg Tablet may cause hypoglycaemia (low blood sugar); hence it advised to take healthy food with enough calories and avoid heavy exercises. Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Oxramet 5/500 mg Tablet , let your doctor know if you have any medical history of heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, low blood pressure, and yeast infection of genitals. It is advised to avoid your alcohol intake while using Oxramet 5/500 mg Tablet to decrease the risk of lactic acidosis. Oxramet 5/500 mg Tablet is not recommended for use during the second or third trimester of pregnancy and breastfeeding.

Uses of Oxramet 5/500 mg Tablet

Type 2 Diabetes mellitus.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it. Take it preferably with a meal since it lowers blood sugar levels and may cause gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Medicinal Benefits

Oxramet 5/500 mg Tablet treats type 2 diabetes mellitus and contains Metformin and Dapagliflozin. Metformin is a biguanide and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. Metformin is considered a unique antidiabetic drug since it does not cause hypoglycemia (lowered blood sugar levels). Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine. Oxramet 5/500 mg Tablet also reduces the risk of heart failure in patients with type 2 diabetes and heart disease. Oxramet 5/500 mg Tablet may be advised with or without other medications along with diet and exercise to control blood sugar levels.

Storage

Keep out of sight and reach of children.

Side effects of Oxramet 5 mg/500 mg Tablet

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Common Cold

Here are the steps to manage the medication-triggered Common Cold:

Inform your doctor about the common cold symptoms you're experiencing due to medication.
Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Low Blood Sugar

If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
Make medication adjustments as recommended by your doctor to prevent future episodes.
Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
Monitor your blood sugar levels closely for patterns and changes.
Track your progress by recording your blood sugar levels, food intake, and physical activity.
Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Inform your doctor if you take other antidiabetic drugs so that the dosage of Oxramet 5/500 mg Tablet will be adjusted accordingly. Do not abruptly stop taking Oxramet 5/500 mg Tablet midway if the doctor did not advise you. Oxramet 5/500 mg Tablet may cause hypoglycaemia (low blood sugar); hence it is advised to make healthy food with enough calories and avoid heavy exercises. Brief your medical history to doctor if you have any heart, kidney or liver diseases, breathing problems (asthma, obstructive lung diseases), blood problems like anaemia (lack of blood cells), vitamin B12 deficiency, pancreas problems/surgery, dehydration, alcohol use, low blood pressure, and yeast infection of genitals before taking Oxramet 5/500 mg Tablet . Avoid alcohol intake while using Oxramet 5/500 mg Tablet since it may increase the risk of lactic acidosis. Oxramet 5/500 mg Tablet is not recommended for use during the second or third trimester of pregnancy and breastfeeding. Your doctor may advise alternate medications to control your diabetic condition in such cases. Oxramet 5/500 mg Tablet is not recommended for people younger than 18 years of age.

Drug-Drug Interactions

DapagliflozinGatifloxacin

Critical

MetforminIopamidol

Critical

Drug-Drug Interactions

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DapagliflozinGatifloxacin

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Oxramet 5 mg/500 mg Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gatifloxacin can be taken with Oxramet 5 mg/500 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.

MetforminIopamidol

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Iopamidol with Oxramet 5 mg/500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

MetforminIoglycamic acid

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Ioglycamic acid with Oxramet 5 mg/500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

MetforminIohexol

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Iohexol with Oxramet 5 mg/500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.

MetforminIopromide

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Iopromide with Oxramet 5 mg/500 mg Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Oxramet 5 mg/500 mg Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.

MetforminIocarmic acid

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Oxramet 5 mg/500 mg Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.

MetforminIodixanol

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Iodixanol with Oxramet 5 mg/500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

MetforminIofendylate

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Iofendylate with Oxramet 5 mg/500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.

MetforminIobenzamic acid

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Oxramet 5 mg/500 mg Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.

MetforminIopydol

Critical

How does the drug interact with Oxramet 5 mg/500 mg Tablet:
Co-administration of Iopydol with Oxramet 5 mg/500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Oxramet 5 mg/500 mg Tablet with Iopydol is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Take the medication as directed by the doctor and at regular intervals if you take Oxramet 5/500 mg Tablet for more than once per day. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Oxramet 5/500 mg Tablet .
Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
Eat at regular intervals.
Keep a check on your weight and exercise regularly to keep your heart healthy.
Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas.

Side Effects of Oxramet 5/500 mg Tablet

Nausea
Vomiting
Diarrhoea
Headache
Weakness
Runny nose
Genital infection
Dizziness
Taste changes
Sore throat
Lactic acidosis (build-up of lactic acid in the bloodstream) (rare)
Diabetic ketoacidosis (a diabetic complication with excess blood acids) (rare)

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Author Details

Written By

Divya L

PharmaD

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:37 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Oxramet 5/500 mg Tablet work?

Oxramet 5/500 mg Tablet contains two antidiabetic medicines: Metformin and Dapagliflozin. These drugs lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and also by increasing the activity of insulin.

Does Oxramet 5/500 mg Tablet lower blood sugar levels?

Oxramet 5/500 mg Tablet may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take Oxramet 5/500 mg Tablet with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins or non-diet soda.

Can I use Oxramet 5/500 mg Tablet with other diabetic medications?

Your doctor may advise Oxramet 5/500 mg Tablet with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using Oxramet 5/500 mg Tablet with or without other antidiabetic drugs.

In which conditions, should I stay cautious while using Oxramet 5/500 mg Tablet ?

Oxramet 5/500 mg Tablet should be used with caution in heart, kidney or liver diseases, breathing problems (asthma, obstructive lung disease), blood disorders (anaemia, vitamin B12 deficiency), dehydration, alcohol use, low blood pressure, pancreas problems/surgery, and yeast infection of genitals. Oxramet 5/500 mg Tablet is contraindicated in patients with severe renal impairment and metabolic acidosis/diabetic ketoacidosis.

What precautions do I need to take while using Oxramet 5/500 mg Tablet ?

While using Oxramet 5/500 mg Tablet , if you experience vomiting, stomach/abdominal pain, muscle cramps, sick feeling, severe tiredness, difficulty in breathing, or reduced body temperature and heartbeat, it is important to seek immediate medical help since these are the symptoms of lactic acidosis. Lactic acidosis is a rare but serious complication caused due to accumulation of metformin. It is a medical emergency and needs immediate treatment. Please consult your doctor for further information.

Can I use Oxramet 5/500 mg Tablet if I am already using water pills/diuretics, such as hydrochlorothiazide?

It is not recommended to use Oxramet 5/500 mg Tablet along with water pills/diuretics. Simultaneous use of Oxramet 5/500 mg Tablet and water pills causes dehydration and may increase the risk of lactic acidosis.

What will happen if I miss a dose of Oxramet 5/500 mg Tablet ?

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

HYDROCHLOROTHIAZIDE
IBUPROFEN
CELECOXIB
CIMETIDINE

Special Advise

It is advised to monitor your blood sugar levels regularly.
If you need to undergo any x-ray or CT scan using a dye that should be injected into your veins, your doctor may suggest you stop taking Oxramet 5/500 mg Tablet temporarily.
Regular monitoring of kidney functioning is advised while using Oxramet 5/500 mg Tablet .
Oxramet 5/500 mg Tablet may make you test positive for a urine glucose test, hence inform your doctor in advance that you take Oxramet 5/500 mg Tablet .

Disease/Condition Glossary

Diabetes mellitus, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people aged above 40 years, but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots.