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Reviewed By Hari Kumar , MBBS
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About PTU Tablet 100's

PTU Tablet 100's belongs to the group of anti-thyroid drugs used in the treatment of overactive thyroid (hyperthyroidism), Grave’s disease, thyrotoxicosis, and enlarged thyroid (toxic goitre). PTU Tablet 100's may also be used to lower very high levels of thyroid hormone prior to surgery or radioactive iodine treatment.

PTU Tablet 100's contains 'Propylthiouracil' that regulates the synthesis and release of thyroid hormones by mellowing down the activity of the thyroid gland.

Take PTU Tablet 100's as prescribed. In some cases, PTU Tablet 100's may cause side effects such as nausea, indigestion, headache, body pain or a mild rash. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of PTU Tablet 100's. Keep your doctor informed if you suffer from any autoimmune disorders, blood disorders or liver disease. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. PTU Tablet 100's may cause dizziness, so drive only if you are alert.

Uses of PTU Tablet 100's

Hyperthyroidism, Graves Disease, Enlarged thyroid (toxic goitre), and Thyrotoxicosis.

Directions for Use

Take PTU Tablet 100's exactly as directed by the physician. Swallow it as a whole with a full glass of water. Do not crush, chew or break it.

Medicinal Benefits

PTU Tablet 100's is an anti-thyroid drug used to treat hyperthyroidism and diseases that produce an overactive thyroid. It contains propylthiouracil. PTU Tablet 100's works by inhibiting the formation of new thyroid hormones, thereby regulating the amount of thyroid hormone in the body and slowing down the thyroid gland that was otherwise in overdrive. Hence, PTU Tablet 100's helps in treating and controlling the symptoms of excess thyroid hormone in the body, including anxiety, palpitation, a racing heartbeat, swelling in the neck (goitre), and weight loss. PTU Tablet 100's may also be used to lower very high levels of thyroid hormone prior to surgery or radioactive iodine treatment.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PTU Tablet 100's

  • Nausea
  • Stomach upset
  • Vomiting
  • Muscle pain
  • Rash
  • Hair loss

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of PTU Tablet 100's. Keep your doctor informed if you suffer from any autoimmune disorders, blood disorders or liver disease. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Inform your doctor if you have recently had any surgery or are about to undergo surgery or a dental procedure.

Drug-Drug Interactions

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PropylthiouracilKetoconazole
Severe
PropylthiouracilMipomersen
Severe

Drug-Drug Interactions

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PropylthiouracilKetoconazole
Severe
How does the drug interact with PTU Tablet:
Coadministration of Ketoconazole and PTU Tablet may increase the risk of liver problems.

How to manage the interaction:
Although taking Ketoconazole and PTU Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience fever, chills, joint pain, itching, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
PropylthiouracilMipomersen
Severe
How does the drug interact with PTU Tablet:
Coadministration of Mipomersen with PTU Tablet can increase the risk of liver problems.

How to manage the interaction:
Taking PTU Tablet with Mipomersen together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms such as fever, chills, joint pain, tiredness, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without first consulting your doctor.
PropylthiouracilCarbamazepine
Severe
How does the drug interact with PTU Tablet:
Taking PTU Tablet with carbamazepine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between PTU Tablet and Carbamazepine, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
PropylthiouracilTeriflunomide
Severe
How does the drug interact with PTU Tablet:
Coadministration of Teriflunomide with PTU Tablet can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between PTU Tablet and Teriflunomide, but it can be taken if prescribed by a doctor. However, if you experience any symptoms such as fever, chills, joint pain, itching, tiredness, abdominal pain, dark urine, light stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without first talking to your doctor.
PropylthiouracilLeflunomide
Severe
How does the drug interact with PTU Tablet:
Taking PTU Tablet with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide with PTU Tablet can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain, unusual bleeding, itching, fatigue, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PropylthiouracilClozapine
Severe
How does the drug interact with PTU Tablet:
Combining PTU Tablet with Clozapine can increase the risk of infection.

How to manage the interaction:
Taking PTU Tablet with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, and pain during urination. Do not stop using any medications without a doctor's advice.
PropylthiouracilFluphenazine
Severe
How does the drug interact with PTU Tablet:
Coadministration of Fluphenazine with PTU Tablet can increase the risk of developing infections.

How to manage the interaction:
Co-administration of PTU Tablet with Fluphenazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination. Do not discontinue any medications without first consulting your doctor.
PropylthiouracilLomitapide
Severe
How does the drug interact with PTU Tablet:
Coadministration of lomitapide with PTU Tablet can increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between PTU Tablet and Lomitapide, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, joint pain, itching, tiredness, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue any medications without first consulting a doctor.
PropylthiouracilMethimazole
Severe
How does the drug interact with PTU Tablet:
Taking PTU Tablet with Methimazole can increase the risk of side effects.

How to manage the interaction:
Co-administration of PTU Tablet with Methimazole can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
PropylthiouracilDeferiprone
Severe
How does the drug interact with PTU Tablet:
Coadministration of Deferiprone with Clozapine can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between PTU Tablet and Deferiprone, you can take these medicines together if prescribed by your doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, or burning during urination. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Stick to a low-iodine diet to regulate the level of thyroid hormones in your body.
  • Opt for non-iodised salt, tea, egg whites, honey, maple syrup, fresh fruits, potatoes, and cauliflower to lower the iodine levels in your diet.
  • Make sure your intake of calcium, vitamin D, zinc, iron and selenium is adequate as these are very important in maintaining thyroid health. Have healthy fats, lean meats, green leafy vegetables and oily fish to regulate thyroid functioning.
  • Limit alcohol and caffeine consumption and stop smoking as these may have a negative effect on health. 
  • One of the symptoms of hyperthyroidism is anxiety and stress. Keep your mind at peace by regularly practising meditation.
  • Doing yoga can also be effective in controlling your thyroid hormones and keeping them in check.

Habit Forming

No

Therapeutic Class

THYROID AND ANTITHYROID AGENTS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • COUMADIN
  • DIGOXIN
  • THEOPHYLLINE
  • AMINOPHYLLINE
  • IODINE

Special Advise

  • If you accidentally take extra doses of PTU Tablet 100's, please inform your doctor or go to a hospital immediately. Some of the symptoms of an overdose can be rash, itching, sudden hair loss, feeling sick, dizziness, mood changes, loss of taste, ear pain, blurring of vision, headache.
  • Do not discontinue taking PTU Tablet 100's abruptly or without the advice of the physician.
  • Please know that your doctor may order blood tests to check your tolerance and need of PTU Tablet 100's.

Disease/Condition Glossary

Hyperthyroidism: Hyperthyroidism refers to an overactive thyroid that pumps high levels of thyroid hormones into the body, leading to rapid heartbeat, weight loss, bulging eyes, sweating, anxiety, palpitations etc.

Grave’s disease: It is an autoimmune condition that produces hyperthyroidism.

Toxic goitre: It involves an enlarged thyroid gland with nodules and produces excess thyroid hormone.

Thyrotoxicosis: It is a condition in which the thyroid hormone levels are dangerously high.

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