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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Pacemero-XP Injection

Pacemero-XP Injection belongs to the group of medications called anti-infectives used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Pacemero-XP Injection contains Meropenem and Sulbactam. Meropenem is a type of antibiotic. It works by preventing the formation of the bacterial protective covering, which is required for bacterial survival. Sulbactam is a beta-lactamase inhibitor that reduces resistance and improves Meropenem antibacterial activity.

Pacemero-XP Injection should only be administered under the supervision of a healthcare professional. The dose depends on the type of infection you have, where the infection is in the body, and how severe the infection is. Your doctor will decide on the dose that you need. The common side-effects of Pacemero-XP Injection may include injection site reactions that may occur, including swelling, pain, itching, nausea, vomiting, diarrhoea, headache, and rash. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

To treat your condition effectually, continue using Pacemero-XP Injection for as long as your doctor has prescribed it. Do not use Pacemero-XP Injection without a doctor's advice if you had a skin reaction or irritation to any medicine. Consult your doctor before using Pacemero-XP Injection if you are pregnant or breastfeeding. Do not use Pacemero-XP Injection in more than prescribed doses or longer duration as it may cause adverse effects. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Keep your doctor informed about your health condition and all the medicines you take before taking Pacemero-XP Injection to rule out any side effects. It is not known whether Pacemero-XP Injection can interact with alcohol or may affect your ability to drive. So, please discuss with your doctor the possible risks and benefits before taking this medicine.

Uses of Pacemero-XP Injection

Bacterial infections.

Directions for Use

Pacemero-XP Injection should be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Pacemero-XP Injection contains Meropenem and Sulbactam. Meropenem is an antibiotic that treats the infection by killing the bacteria. Sulbactam is a beta-lactamase (an enzyme produced by bacteria that can destroy antibiotics) inhibitor and prevents the destruction of Meropenem from the bacteria. Pacemero-XP Injection has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It is used to treat bacterial infections such as skin infections, gynecological infections, and intra-abdominal infections.

Storage

Keep Pacemero-XP Injection out of reach and sight of children.

Drug Warnings

It is not recommended to take Pacemero-XP Injection if you are allergic to other antibiotics or this medicine's contents. Pacemero-XP Injection is not recommended for people with infectious mononucleosis (viral infection with sore throat and fever) and colitis (intestine inflammation). Pacemero-XP Injection should be used with caution in patients with kidney impairment. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Should use Pacemero-XP Injection with caution in children, pregnant women, breastfeeding mothers and older people. It is not known whether Pacemero-XP Injection can interact with alcohol or may affect your ability to drive. So, please discuss with your doctor the possible risks and benefits before taking this medicine.

Drug-Drug Interactions

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MeropenemIomeprol
Severe

Drug-Drug Interactions

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How does the drug interact with Pacemero-XP Injection:
Taking Tramadol with Pacemero-XP Injection together may cause higher levels of Pacemero-XP Injection in the blood.

How to manage the interaction:
Taking Pacemero-XP Injection with Tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MeropenemIomeprol
Severe
How does the drug interact with Pacemero-XP Injection:
Co-administration of Iomeprol and Pacemero-XP Injection together can increase the risk of causing seizures.

How to manage the interaction:
Taking Pacemero-XP Injection with Iomeprol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - close monitoring, seizures, or head injury - contact a doctor right away." Do not stop using any medications without talking to a doctor.
MeropenemBCG vaccine
Severe
How does the drug interact with Pacemero-XP Injection:
When BCG vaccine is used with Pacemero-XP Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Pacemero-XP Injection with the BCG vaccine together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pacemero-XP Injection:
Co-administration of Divalproex and Pacemero-XP Injection can reduce the blood levels of Divalproex sodium.

How to manage the interaction:
Co-administration of Divalproex with Pacemero-XP Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
MeropenemMetrizamide
Severe
How does the drug interact with Pacemero-XP Injection:
Co-administration of Metrizamide and Pacemero-XP Injection together can increase the risk of seizures.

How to manage the interaction:
Taking Pacemero-XP Injection with Metrizamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - being closely monitored by your doctor, having seizures, or having a condition or head injury - contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pacemero-XP Injection:
Co-administration of Meropenam and Sodium valproate together can reduce the effect of Sodium valproate.

How to manage the interaction:
Co-administration of Meropenam and Sodium valproate can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking an entire course of Pacemero-XP Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
  • Avoid alcoholic beverages with Pacemero-XP Injection as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Pacemero-XP Injection in fighting off infections.

Side Effects of Pacemero-XP Injection

  • Stomach pain
  • Feeling sick (nausea)
  • Vomiting
  • Diarrhoea
  • Headache
  • Pain and inflammation
  • A tingling feeling

Habit Forming

No

Therapeutic Class

ANTI- INFECTIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Pacemero-XP Injection is used to treat bacterial infections. It contains Meropenem and Sulbactam. Meropenem reduces the infection by inhibiting bacterial growth. It disrupts the cell wall formation (outer layer), which is essential for bacteria's survival. Sulbactam inhibits the action of beta-lactamase, an enzyme produced by the bacteria to destroy antibiotics (Meropenem).

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.

Do not stop using Pacemero-XP Injection even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and to worsening of the disease.

Pacemero-XP Injection should not be given to the people with infectious mononucleosis (viral infection with sore throat and fever) and colitis (inflammation of the intestine) as Pacemero-XP Injection worsen these conditions.

Drug-Drug Interactions Checker List

  • VALPROIC ACID
  • SODIUM VALPROATE
  • PROBENECID
  • DABIGATRAN
  • APIXABAN

Special Advise

  • When administering prolonged therapy, monitor renal, hepatic, and hematologic functions periodically. Also monitor for signs of anaphylaxis during the first dose.
  • Even if you feel better after taking Pacemero-XP Injection, do not stop taking it until your doctor says so. It might cause the symptoms to reappear and make the infection difficult to treat due to antibiotic resistance.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any organ of the body and multiply very quickly. Bacterial infections vary from minor illnesses (like sore throat and ear infections) to severe brain infections (like meningitis and encephalitis). When infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue.  Few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.

Have a query?

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Alcohol

Caution

Alcohol may increase the side effects of Pacemero-XP Injection. Hence, it is advised to limit the intake of alcohol while using Pacemero-XP Injection.

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Pregnancy

Caution

Pacemero-XP Injection should be used in pregnant women only if clinically needed when the benefits outweigh the risks. Your doctor will weigh the benefits and any potential risks before prescribing Pacemero-XP Injection.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on the use of Pacemero-XP Injection in breastfeeding/nursing mothers.

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Driving

Caution

It is not known whether Pacemero-XP Injection alters the ability to drive. Do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Pacemero-XP Injection should be used with caution in patients with liver diseases as it may affect liver function. The dose may have to be adjusted by your doctor. Please consult the doctor.

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Kidney

Caution

Pacemero-XP Injection should be used with caution in patients with kidney diseases. Your doctor will weigh the benefits and any potential risks before prescribing Pacemero-XP Injection.

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Children

Caution

Pacemero-XP Injection should be used in children only if clinically needed. The doctor may have to adjust the dose based on age, body weight and medical history.

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