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Reviewed By Hari Kumar , MBBS
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Composition :

PALBOCICLIB-100MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Palbace 100Mg 21 Capsule

Palbace 100Mg 21 Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Palbace 100Mg 21 Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Palbace 100Mg 21 Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Palbace 100Mg 21 Capsule as prescribed. In some cases, Palbace 100Mg 21 Capsule may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbace 100Mg 21 Capsule if you are pregnant or breastfeeding. Palbace 100Mg 21 Capsule may cause tiredness, so drive only if you are alert. Palbace 100Mg 21 Capsule is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Palbace 100Mg 21 Capsule

Breast Cancer

Directions for Use

Take Palbace 100Mg 21 Capsule preferably with a meal. Swallow it as a whole with water. Do not crush, chew or break it.

Medicinal Benefits

Palbace 100Mg 21 Capsule is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Palbace 100Mg 21 Capsule works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Palbace 100Mg 21 Capsule nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Palbace 100Mg 21 Capsule helps treat breast cancer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Palbace 100Mg 21 Capsule. It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbace 100Mg 21 Capsule if you are pregnant or breastfeeding. Palbace 100Mg 21 Capsule may cause tiredness, so drive only if you are alert. Palbace 100Mg 21 Capsule is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

FAQs

Palbace 100Mg 21 Capsule works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.

Do not stop taking Palbace 100Mg 21 Capsule on your own. You are advised to take Palbace 100Mg 21 Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Palbace 100Mg 21 Capsule.

A fibroadenoma is a benign state. Palbace 100Mg 21 Capsule is indicated only in case of cancers. Please consult your doctor in case of any concerns.

Palbace 100Mg 21 Capsule can reduce fertility in men. Therefore, consider sperm preservation before starting Palbace 100Mg 21 Capsule if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Palbace 100Mg 21 Capsule.

Palbace 100Mg 21 Capsule may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.

Drug-Drug Interactions Checker List

  • RITONAVIR
  • NELFINAVIR
  • SAQUINAVIR
  • LOPINAVIR
  • TELAPREVIR
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ABATACEPT
  • QUINIDINE
  • COLCHICINE
  • ALFENTANIL
  • FENTANYL
  • TACROLIMUS
  • CYCLOSPORINE
  • PIMOZIDE
  • ERGOTAMINE

Special Advise

  • Discuss contraception with your doctor while taking Palbace 100Mg 21 Capsule.
  • People on treatment with Palbace 100Mg 21 Capsule should use additional contraception (barrier method such as condoms). Contraception should be continued 3 weeks post-treatment for women and 14 weeks post-treatment for men.
  • You may want to consider sperm storage before starting Palbace 100Mg 21 Capsule. Seek counsel on the same from a qualified healthcare individual and/or sperm bank. 
  • Regular complete blood count monitoring is advised.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer that develops in breast cells. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm. 

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