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Paliris LA 75 mg PFS Injection 0.75 ml

Paliris LA 75 mg PFS Injection 0.75 ml

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Prescription drug
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Synonym

PALIPERIDONE PALMITATE

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Paliris LA 75 mg PFS Injection 0.75 ml

Paliris LA 75 mg PFS Injection 0.75 ml belongs to a group of medicines called 'antipsychotics' used for the treatment of schizophrenia and schizoaffective disorder in adults as monotherapy and as an adjunct to mood stabilizers or antidepressants. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

Paliris LA 75 mg PFS Injection 0.75 ml contains 'Paliperidone' that works by blocking the effects of chemical messengers in the brain (i.e., dopamine and serotonin), thereby helping improve mood, behaviour and thoughts. Paliris LA 75 mg PFS Injection 0.75 ml elevates the symptoms of the disease and prevents them from recurring.

Paliris LA 75 mg PFS Injection 0.75 ml is for intramuscular injection only. It should be given by experienced healthcare professionals. In some cases, you may experience common side effects such as injection site reactions, sleepiness or drowsiness, feeling restlessness or needing to be constantly moving, dizziness, abnormal muscle movements including tremor (shaking), uncontrolled involuntary movements, shuffling and abnormal movements of your eyes. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Paliris LA 75 mg PFS Injection 0.75 ml is restricted to use in people who are sensitive to paliperidone, risperidone, or any excipients in the formulation. Keep your doctor informed about your health condition and medicines to rule out any side effects. Before using Paliris LA 75 mg PFS Injection 0.75 ml, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Paliris LA 75 mg PFS Injection 0.75 ml is recommended not to use in children. Avoid consuming alcohol with Paliris LA 75 mg PFS Injection 0.75 ml as it could lead to increased drowsiness and dizziness. Paliris LA 75 mg PFS Injection 0.75 ml may impair your ability to make judgements, think clearly, or respond fast. Do not drive, operate heavy machinery, or engage in any other risky activity.

Uses of Paliris LA 75 mg PFS Injection 0.75 ml

Schizophrenia

Medicinal Benefits

Paliris LA 75 mg PFS Injection 0.75 ml belongs to a group of medicines called antipsychotics used to treat schizophrenia in adults. Paliris LA 75 mg PFS Injection 0.75 ml improves mood and behaviour in people with an imbalance of chemicals known as neurotransmitters in their brains. Thus, Paliris LA 75 mg PFS Injection 0.75 ml relieves psychotic symptoms like delusions, hallucinations, confusion, disturbing thoughts and lack of self-awareness.

Directions for Use

For intramuscular injection only. It must be administered only by a healthcare professional.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Paliris LA 75 mg PFS Injection 0.75 ml

  • Dementia-related psychosis
  • Stroke
  • Dementia-Related psychosis
  • Neuroleptic malignant syndrome
  • QT prolongation
  • Tardive dyskinesia (involuntary movements)
  • Metabolic changes orthostatic hypotension and syncope
  • Falls
  • Leukopenia or Neutropenia (low levels of white blood cells)
  • Agranulocytosis
  • Hyperprolactinemia
  • Potential for cognitive and motor impairment
  • Seizures
  • Dysphagia (swallowing difficulties)
  • Priapism (prolonged erection of the penis)
  • Disruption of body temperature regulation
  • Dry mouth
  • Abdominal pain/Discomfort
  • Nausea
  • Diarrhoea
  • High fever
  • Severe muscle stiffness
  • Confusion
  • Loss of consciousness
  • Changes in your breathing, heartbeat and blood pressure

Drug Warnings

Let your doctor know before prescribing Paliris LA 75 mg PFS Injection 0.75 ml if you are sensitive to paliperidone, risperidone, or any excipients in the formulation. Keep your doctor informed about your health condition and medicines to rule out any side effects. Before using the Paliris LA 75 mg PFS Injection 0.75 ml, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Paliris LA 75 mg PFS Injection 0.75 ml is recommended not to use in children. Avoid consuming alcohol with Paliris LA 75 mg PFS Injection 0.75 ml as it could lead to increased drowsiness and dizziness. Paliris LA 75 mg PFS Injection 0.75 ml has the potential to impair your capacity to make judgements, think clearly, or respond swiftly. Avoid being dehydrated or overheated.

Drug Interactions

Drug-Drug Interactions: Paliris LA 75 mg PFS Injection 0.75 ml may have interaction with antipsychotic medicines (e.g. haloperidol), medicines used to treat anxiety and sleeping problems (e.g. lorazepam), anti-depression medications (e.g. duloxetine), anti-allergic medications (e.g. diphenhydramine) and medicines used to treat schizophrenia and bipolar disorder (aripiprazole).

Drug-Food Interactions: Paliris LA 75 mg PFS Injection 0.75 ml may interact with alcohol. Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Paliris LA 75 mg PFS Injection 0.75 ml may have interactions with disease conditions including dementia (memory loss), irregular heartbeat (with QT interval prolongation), Neuroleptic Malignant Syndrome, aspiration, seizure, hematologic abnormalities, hyperglycemia/diabetes, hypotension, lipid alterations, priapism, weight gain, depression, hyperprolactinemia, tardive dyskinesia, antiemetic effect and gastrointestinal obstruction.

Drug-Drug Interactions Checker List

  • HALOPERIDOL
  • LORAZEPAM
  • DULOXETINE
  • DIPHENHYDRAMINE
  • ARIPIPRAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Disease/Condition Glossary

Schizophrenia: It is a condition where a person experiences unusually suspicious or confused feelings, believes things that are not true, or perceives, hears, or feels things that are not there. Hallucinations, delusions, movement disorders, disordered thinking, loss of interest, lack of emotions, and more are among the symptoms.

Country of origin

India
Other Info - PAL0261

FAQs

Paliris LA 75 mg PFS Injection 0.75 ml works by balancing the chemical messengers called neurotransmitters and blocking the effect of dopamine and serotonin located in the brain, thereby helping in improving mood, behaviour and thoughts.
Paliris LA 75 mg PFS Injection 0.75 ml may cause metabolic changes: So it is recommended to monitor for hyperglycemia/diabetes mellitus, dyslipidemia and weight gain. If you experience any major changes inform the doctor immediately.
Paliris LA 75 mg PFS Injection 0.75 ml may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Paliris LA 75 mg PFS Injection 0.75 ml. Diabetes patients should discuss with a doctor before taking Paliris LA 75 mg PFS Injection 0.75 ml.
Yes, orthostatic hypotension could be a side-effect of Paliris LA 75 mg PFS Injection 0.75 ml. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Paliris LA 75 mg PFS Injection 0.75 ml are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.
Paliris LA 75 mg PFS Injection 0.75 ml may make you sweat less, making you more likely to get heatstroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather, or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly.
Dry mouth could be a side-effect of Paliris LA 75 mg PFS Injection 0.75 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Paliris LA 75 mg PFS Injection 0.75 ml is known to cause increased mortality in people who are elderly with dementia. So, please inform your doctor if you have dementia; before starting Paliris LA 75 mg PFS Injection 0.75 ml.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid consumption of alcohol while taking Paliris LA 75 mg PFS Injection 0.75 ml as it may cause increased drowsiness and lower your blood pressure.

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Pregnancy

Caution

Paliris LA 75 mg PFS Injection 0.75 ml is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Paliris LA 75 mg PFS Injection 0.75 ml.

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Breast Feeding

Caution

Caution should be exercised. Paliris LA 75 mg PFS Injection 0.75 ml is not recommended for use in breastfeeding unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Paliris LA 75 mg PFS Injection 0.75 ml.

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Driving

Unsafe

Paliris LA 75 mg PFS Injection 0.75 ml may affect your ability to make decisions, think clearly, or react quickly. Do not drive, operate heavy machinery, or do other dangerous activities.

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Liver

Caution

Inform your doctor if you have a liver impairment. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Inform your doctor if you have kidney impairment. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

The safety and efficacy of Paliris LA 75 mg PFS Injection 0.75 ml are not established in children under the age of 18 years.

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