Paliris LA 75 mg PFS Injection 0.75 ml belongs to a group of medicines called 'antipsychotics' used for the treatment of schizophrenia and schizoaffective disorder in adults as monotherapy and as an adjunct to mood stabilizers or antidepressants. Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

Paliris LA 75 mg PFS Injection 0.75 ml contains 'Paliperidone' that works by blocking the effects of chemical messengers in the brain (i.e., dopamine and serotonin), thereby helping improve mood, behaviour and thoughts. Paliris LA 75 mg PFS Injection 0.75 ml elevates the symptoms of the disease and prevents them from recurring.

Paliris LA 75 mg PFS Injection 0.75 ml is for intramuscular injection only. It should be given by experienced healthcare professionals. In some cases, you may experience common side effects such as injection site reactions, sleepiness or drowsiness, feeling restlessness or needing to be constantly moving, dizziness, abnormal muscle movements including tremor (shaking), uncontrolled involuntary movements, shuffling and abnormal movements of your eyes. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Paliris LA 75 mg PFS Injection 0.75 ml is restricted to use in people who are sensitive to paliperidone, risperidone, or any excipients in the formulation. Keep your doctor informed about your health condition and medicines to rule out any side effects. Before using Paliris LA 75 mg PFS Injection 0.75 ml, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Paliris LA 75 mg PFS Injection 0.75 ml is recommended not to use in children. Avoid consuming alcohol with Paliris LA 75 mg PFS Injection 0.75 ml as it could lead to increased drowsiness and dizziness. Paliris LA 75 mg PFS Injection 0.75 ml may impair your ability to make judgements, think clearly, or respond fast. Do not drive, operate heavy machinery, or engage in any other risky activity.

Paliris LA 75 mg PFS Injection 0.75 ml belongs to a group of medicines called antipsychotics used to treat schizophrenia in adults. Paliris LA 75 mg PFS Injection 0.75 ml improves mood and behaviour in people with an imbalance of chemicals known as neurotransmitters in their brains. Thus, Paliris LA 75 mg PFS Injection 0.75 ml relieves psychotic symptoms like delusions, hallucinations, confusion, disturbing thoughts and lack of self-awareness.

• Dementia-related psychosis
• Stroke
• Dementia-Related psychosis
• Neuroleptic malignant syndrome
• QT prolongation
• Tardive dyskinesia (involuntary movements)
• Metabolic changes orthostatic hypotension and syncope
• Falls
• Leukopenia or Neutropenia (low levels of white blood cells)
• Agranulocytosis
• Hyperprolactinemia
• Potential for cognitive and motor impairment
• Seizures
• Dysphagia (swallowing difficulties)
• Priapism (prolonged erection of the penis)
• Disruption of body temperature regulation
• Dry mouth
• Abdominal pain/Discomfort
• Nausea
• Diarrhoea
• High fever
• Severe muscle stiffness
• Confusion
• Loss of consciousness
• Changes in your breathing, heartbeat and blood pressure

Let your doctor know before prescribing Paliris LA 75 mg PFS Injection 0.75 ml if you are sensitive to paliperidone, risperidone, or any excipients in the formulation. Keep your doctor informed about your health condition and medicines to rule out any side effects. Before using the Paliris LA 75 mg PFS Injection 0.75 ml, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Paliris LA 75 mg PFS Injection 0.75 ml is recommended not to use in children. Avoid consuming alcohol with Paliris LA 75 mg PFS Injection 0.75 ml as it could lead to increased drowsiness and dizziness. Paliris LA 75 mg PFS Injection 0.75 ml has the potential to impair your capacity to make judgements, think clearly, or respond swiftly. Avoid being dehydrated or overheated.

Drug-Drug Interactions: Paliris LA 75 mg PFS Injection 0.75 ml may have interaction with antipsychotic medicines (e.g. haloperidol), medicines used to treat anxiety and sleeping problems (e.g. lorazepam), anti-depression medications (e.g. duloxetine), anti-allergic medications (e.g. diphenhydramine) and medicines used to treat schizophrenia and bipolar disorder (aripiprazole).

Drug-Food Interactions: Paliris LA 75 mg PFS Injection 0.75 ml may interact with alcohol. Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Paliris LA 75 mg PFS Injection 0.75 ml may have interactions with disease conditions including dementia (memory loss), irregular heartbeat (with QT interval prolongation), Neuroleptic Malignant Syndrome, aspiration, seizure, hematologic abnormalities, hyperglycemia/diabetes, hypotension, lipid alterations, priapism, weight gain, depression, hyperprolactinemia, tardive dyskinesia, antiemetic effect and gastrointestinal obstruction.

• HALOPERIDOL
• LORAZEPAM
• DULOXETINE
• DIPHENHYDRAMINE
• ARIPIPRAZOLE

• Maintain proper weight by following a healthy diet.
• Exercise regularly as it helps in less cognitive decline and brain volume loss.
• Avoid smoking and alcohol consumption.
• Try to avoid stress by practising meditation or yoga.
• Include fruits and vegetables in your diet as they contain antioxidants.
• Eat nutritious food as it helps in cognitive stimulation.
• Limit foods with high cholesterol and saturated fats.
• Cut down on sugar, salt and processed foods.
• Drink plenty of water.
• Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.
• Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Schizophrenia: It is a condition where a person experiences unusually suspicious or confused feelings, believes things that are not true, or perceives, hears, or feels things that are not there. Hallucinations, delusions, movement disorders, disordered thinking, loss of interest, lack of emotions, and more are among the symptoms.