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Written By Divya L , PharmaD
Reviewed By Santoshini Reddy G , M Pharmacy

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Composition :

PANTOPRAZOLE-40MG

Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Pantafol Injection 10 ml

Pantafol Injection 10 ml is a proton pump inhibitor, primarily used to treat gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis (acid-related damage to the oesophagus lining), Zollinger-Ellison syndrome and other conditions caused due to excessive acid in the stomach. GERD is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

Pantafol Injection 10 ml contains Pantoprazole. It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. 

Pantafol Injection 10 ml will be administered by a healthcare professional. Common side effects of Pantafol Injection 10 ml include headache, dizziness, diarrhoea, nausea, vomiting, stomach pain, gas, joint pain, pain, redness, and swelling at the injection site. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are sensitive or allergic to Pantafol Injection 10 ml or other medications. Before using Pantafol Injection 10 ml, let your doctor know if you have any liver, kidney or heart diseases and gastrointestinal problems. Pregnant and breastfeeding women should consult their doctor before using Pantafol Injection 10 ml. Pantafol Injection 10 ml may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol intake while using Pantafol Injection 10 ml since it can increase acid production in the stomach. Pantafol Injection 10 ml is not recommended for children below five years of age.

Uses of Pantafol Injection 10 ml

Stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis, and Zollinger-Ellison syndrome.

Directions for Use

Pantafol Injection 10 ml will be injected by a healthcare professional. Do not self-administer.

Medicinal Benefits

Pantafol Injection 10 ml contains Pantoprazole, which is a proton pump inhibitor. It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. It also relieves the symptoms of GERD like heartburn, difficulty in swallowing, and persistent cough. Pantoprazole may also prevent oesophageal cancer.

Storage

Keep out of sight and reach of children.

Drug Warnings

Let your doctor know if you are sensitive to any of the components in Pantafol Injection 10 ml. Pantafol Injection 10 ml should be used with caution and only under a doctor’s supervision if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, and autoimmune diseases like lupus. Long term treatment with Pantafol Injection 10 ml may increase the risk of fractures of the hip, spine, and wrist. Hence, inform your doctor if you have osteoporosis and bone-related problems. Pantafol Injection 10 ml may also cause low Vitamin B12 levels on long term usage. Hence let your doctor know if you have Vitamin B12 deficiency before starting Pantafol Injection 10 ml. Let your doctor know if you are pregnant or a nursing mother before starting Pantafol Injection 10 ml. Pantafol Injection 10 ml may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol intake while using Pantafol Injection 10 ml since it can increase acid production in the stomach. Pantafol Injection 10 ml is recommended for children above five years of age only when prescribed by a doctor.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time; instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomfort.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids to prevent dehydration.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Author Details

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FAQs

Pantafol Injection 10 ml works by reducing the amount of acid produced in the stomach and thus relieves stomach ulcers, heartburn, GERD, and other gastrointestinal discomforts.

Pantafol Injection 10 ml should be used with caution and only under a doctor’s supervision if you have any liver, kidney or heart diseases, stomach and intestinal problems, recent abdominal surgery, Vitamin B12 deficiency, risk of bone fractures, osteoporosis, and autoimmune diseases like lupus.

Please do not take Pantafol Injection 10 ml for longer durations unless prescribed by the doctor. Taking Pantafol Injection 10 ml on long-term may cause you to develop stomach growths known as fundic gland polyps. A regular check-up is advised if Pantafol Injection 10 ml is prescribed for longer durations.

Pantafol Injection 10 ml may cause bloating as a side effect with its regular use. You may experience tightness, fullness, or swelling of your stomach area. It is advised to avoid consuming wind/gas-producing foods like beans, onions, lactose-containing foods, and carbonated beverages. You can also try herbal teas like peppermint, coriander, fennel, turmeric, and chamomile. If you do not notice any improvement in your bloating, please seek medical advice.

Diarrhoea might be a side-effect of Pantafol Injection 10 ml. Drink lots of fluids and eat non-spicy foods if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Prolonged intake of proton pump inhibitors like Pantafol Injection 10 ml is linked with a greater risk of Clostridium difficile-associated diarrhoea. If you develop diarrhoea that does not improve, immediately consult a doctor.

On long term treatment, Pantafol Injection 10 ml may increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis, bone-related problems, or take any corticosteroids. Your doctor may suggest supplements like Calcium citrate and Vitamin D.

Pantafol Injection 10 ml may cause low Vitamin B12 levels on long term usage. Your doctor may adjust the dose of Pantafol Injection 10 ml accordingly and may suggest Vitamin B12 supplements if you are on long term treatment with Pantafol Injection 10 ml.

Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • METHOTREXATE
  • DIGOXIN

Special Advise

  • Your doctor may suggest diagnostic procedures like endoscopy or colonoscopy to understand your condition and its severity.
  • Pantafol Injection 10 ml may interfere with urine tests for tetrahydrocannabinol-THC and blood tests to find certain tumours. Inform your doctor and laboratory staff that you are taking Pantafol Injection 10 ml before undergoing examinations.

Disease/Condition Glossary

Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, stomach ulcer, and Zollinger Ellison syndrome.

Gastroesophageal reflux disease (GERD): It is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms of GERD include chest pain, difficulty swallowing, regurgitation (expulsion of food from the pharynx or oesophagus) of food/sour liquid, and a burning sensation in the chest.

Zollinger Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers. Symptoms include abdominal pain, diarrhoea, heartburn, acid reflux, and burping.

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