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  3. Pancruz DSR Capsule 10's

Pancruz DSR Capsule 10's, Pack of 10
Pancruz DSR Capsule 10's, Pack of 10
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
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Whats That

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Composition :

DOMPERIDONE-30MG + PANTOPRAZOLE-40MG

Manufacturer/Marketer :

Biorex Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pancruz DSR Capsule

Pancruz DSR Capsule is composed of two medicines, namely: Domperidone and Pantoprazole. Domperidone is a prokinetic and anti-nausea agent that helps to treat indigestion and stomach pain. On the other hand, Pantoprazole is a proton pump inhibitor that reduces the excess stomach acid formation by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). Pancruz DSR Capsule is a widely used medicine to treat peptic ulcers and gastroesophageal reflux disease (GERD). Pancruz DSR Capsule prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, that is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.

It should be taken as prescribed by the doctor. Like all medicines, Pancruz DSR Capsule may cause side effects, although not everybody gets them. The most common side effects of Pancruz DSR Capsule are diarrhoea, stomach pain, flatulence (gas), dryness in the mouth, dizziness, and headache. Everyone doesn't need to experience the above side effects. In case of any discomfort, speak with your doctor.

It is recommended not to use if you are allergic to any ingredinets present in it. Prolonged intake of Pantoprazole is associated with a low level of Vitamin B12 and low magnesium. Hence yearly test of Vitamin B12 and magnesium is required if you are taking Pancruz DSR Capsule for the long term. Use of Pancruz DSR Capsule is contraindicated in people with lupus (autoimmune inflammatory disease). Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated drinks, acidic foods like citrus fruits/vegetables (tomatoes).

Uses of Pancruz DSR Capsule

Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), Peptic ulcer.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Pancruz DSR Capsule plays a vital role in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions due to hyperacidity or acid reflux. Pantoprazole prevents the proton pumps gate from producing an excessive amount of stomach acid. While Domperidone stops nausea (feeling sick) and vomiting (being sick) blocking messages between parts of your brain called the chemoreceptor trigger zone (CTZ) and the vomiting centre.

Drug Warnings

You should avoid taking Pancruz DSR Capsule if you are allergic to Pancruz DSR Capsule or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Pancruz DSR Capsule may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Pancruz DSR Capsule may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Pancruz DSR Capsule may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
PantoprazoleNelfinavir
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Pancruz DSR Capsule:
Co-administration of Rilpivirine is taken with Pancruz DSR Capsule, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Pancruz DSR Capsule with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PantoprazoleNelfinavir
Severe
How does the drug interact with Pancruz DSR Capsule:
Taking Nelfinavir with Pancruz DSR Capsule may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Pancruz DSR Capsule with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazolePazopanib
Severe
How does the drug interact with Pancruz DSR Capsule:
Taking Pancruz DSR Capsule with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Pancruz DSR Capsule and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PantoprazoleDasatinib
Severe
How does the drug interact with Pancruz DSR Capsule:
Taking Dasatinib with Pancruz DSR Capsule may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Pancruz DSR Capsule with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
PantoprazoleMethotrexate
Severe
How does the drug interact with Pancruz DSR Capsule:
Co-administration of Methotrexate with Pancruz DSR Capsule can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Pancruz DSR Capsule and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
PantoprazoleAtazanavir
Severe
How does the drug interact with Pancruz DSR Capsule:
Co-administration of Pancruz DSR Capsule reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Pancruz DSR Capsule with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleGefitinib
Severe
How does the drug interact with Pancruz DSR Capsule:
Taking Gefitinib with Pancruz DSR Capsule reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Pancruz DSR Capsule with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Pancruz DSR Capsule to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
PantoprazoleErlotinib
Severe
How does the drug interact with Pancruz DSR Capsule:
Taking Erlotinib with Pancruz DSR Capsule may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Pancruz DSR Capsule with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleDacomitinib
Severe
How does the drug interact with Pancruz DSR Capsule:
Taking Pancruz DSR Capsule can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Pancruz DSR Capsule with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
DomperidoneClarithromycin
Severe
How does the drug interact with Pancruz DSR Capsule:
Coadministration of Pancruz DSR Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Pancruz DSR Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Pancruz DSR Capsule Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone - CTZ) located in your brain, which is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.

Pancruz DSR Capsule can be safely taken as long as your doctor has prescribed it to you.

Yes, taking Pancruz DSR Capsule for a very long time can cause calcium depletion from the body leading to weakening of bones. Hence a calcium and vitamin D supplement is recommended along with Pancruz DSR Capsule to replenish calcium depletion in the body.

Yes. Pancruz DSR Capsule can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

Prolonged intake of Pancruz DSR Capsule may weaken your bone and lower haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

Combination of pantoprazole and domperidone is effective & safe.

No, Pancruz DSR Capsule is a prescribed drug with minimal side effects. Only take it if your doctor has recommended it to you for acidity.

Drug-Drug Interactions Checker List

  • CLOPIDOGREL
  • WARFARIN
  • KETOCONAZOLE
  • VORICONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • ATAZANAVIR
  • NELFINAVIR
  • AMPICILLIN
  • RIFAMPICIN
  • DIGOXIN
  • METHOTREXATE

Disease/Condition Glossary

Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, a peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

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