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Prescription drugWhats That
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Parentacin 150mg Injection:
Co-administration of Parentacin 150mg Injection with Balsalazide may reduce the effectiveness of Balsalazide.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Co-administration of Parentacin 150mg Injection with Balsalazide may reduce the effectiveness of Balsalazide.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with balsalazide if prescribed by the doctor. Consult the prescriber if you have any concerns, the doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Parentacin 150mg Injection:
Co-administration of of Parentacin 150mg Injection with gentamicin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
Co-administration of of Parentacin 150mg Injection with gentamicin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with gentamicin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.
ClindamycinBacitracin
Severe
How does the drug interact with Parentacin 150mg Injection:
Co-administration of Parentacin 150mg Injection with Bacitracin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with bacitracin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.
Co-administration of Parentacin 150mg Injection with Bacitracin may increase the risk of kidney and/or nerve damage.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with bacitracin if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.
ClindamycinCholera, live attenuated
Severe
How does the drug interact with Parentacin 150mg Injection:
Co-administration of Parentacin 150mg Injection may reduce the activity of the cholera vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Parentacin 150mg Injection or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
Co-administration of Parentacin 150mg Injection may reduce the activity of the cholera vaccine.
How to manage the interaction:
Talk to your doctor before receiving the Cholera vaccine if you are currently being treated with Parentacin 150mg Injection or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete antibiotic therapy. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Parentacin 150mg Injection:
Taking Parentacin 150mg Injection with Botulinum toxin can increase the risk or severity of side effects.
How to manage the interaction:
Taking Parentacin 150mg Injection with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Parentacin 150mg Injection with Botulinum toxin can increase the risk or severity of side effects.
How to manage the interaction:
Taking Parentacin 150mg Injection with Botulinum toxin together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClindamycinAmprenavir
Severe
How does the drug interact with Parentacin 150mg Injection:
Co-administration of Amprenavir together with Parentacin 150mg Injection can increase the effects of Parentacin 150mg Injection.
How to manage the interaction:
Co-administration of Parentacin 150mg Injection with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Amprenavir together with Parentacin 150mg Injection can increase the effects of Parentacin 150mg Injection.
How to manage the interaction:
Co-administration of Parentacin 150mg Injection with Amprenavir can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have ongoing feelings of sickness, throwing up, having loose stools, or pain in your stomach, it's important to contact your doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Parentacin 150mg Injection:
Taking Parentacin 150mg Injection with clarithromycin may increase the effects of Parentacin 150mg Injection.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with clarithromycin if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not discontinue the medication without consulting a doctor.
Taking Parentacin 150mg Injection with clarithromycin may increase the effects of Parentacin 150mg Injection.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with clarithromycin if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhea. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Parentacin 150mg Injection:
Concomitant use of Parentacin 150mg Injection with ceritinib can increase the effects of Parentacin 150mg Injection
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
Concomitant use of Parentacin 150mg Injection with ceritinib can increase the effects of Parentacin 150mg Injection
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with ceritinib if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain, or diarrhoea.
Severe
How does the drug interact with Parentacin 150mg Injection:
Coadministration of use of Parentacin 150mg Injection with ketoconazole can increase the effects of Parentacin 150mg Injection.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
Coadministration of use of Parentacin 150mg Injection with ketoconazole can increase the effects of Parentacin 150mg Injection.
How to manage the interaction:
Although there is a possible interaction, Parentacin 150mg Injection can be taken with ketoconazole if prescribed by the doctor. Consult the prescriber if you experience persistent vomiting, nausea, abdominal pain or diarrhea. Do not discontinue any medication without consulting a doctor. Do not discontinue any medication without consulting a doctor.
Severe
How does the drug interact with Parentacin 150mg Injection:
Co-administration of Capreomycin with Parentacin 150mg Injection can increase the risk of kidney or nerve damage.
How to manage the interaction:
There may be a possibility of interaction between Parentacin 150mg Injection and Capreomycin, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
Co-administration of Capreomycin with Parentacin 150mg Injection can increase the risk of kidney or nerve damage.
How to manage the interaction:
There may be a possibility of interaction between Parentacin 150mg Injection and Capreomycin, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
CLINDAMYCIN-150MG/MLOther bacterial intestinal infections
Severe
CLINDAMYCIN-150MG/MLDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
Drug-Diseases Interactions
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CLINDAMYCIN-150MG/MLOther bacterial intestinal infections
Severe
How does the disease interact with Parentacin 150mg Injection:
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
Almost all antibacterial medications have been associated with reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis.
How to manage the interaction:
Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis has been reported during treatment with antibacterial agents. Therapy should be administered cautiously in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, and antibacterial treatment of C difficile is advised.
CLINDAMYCIN-150MG/MLDisorders related to short gestation and low birth weight, not elsewhere classified
Severe
How does the disease interact with Parentacin 150mg Injection:
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
Benzyl alcohol is frequently used as a preservative in the formulation of multidose vials for parenteral medicines. Manufacturers of pharmaceuticals believe that using them in neonates, especially preterm and underweight newborns, is contraindicated. In low birth weight preterm newborns, the use of benzyl alcohol in bacteriostatic saline intravascular flush and endotracheal tube lavage solutions has been linked to mortality and serious respiratory and metabolic problems.
How to manage the interaction:
Parenteral medications containing benzyl alcohol as a preservative are contraindicated in neonates, particularly premature infants and infants of low birth weight.
CLINDAMYCIN-150MG/MLOther diseases of liver
Moderate
How does the disease interact with Parentacin 150mg Injection:
The liver is the primary site of Parentacin 150mg Injection metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Parentacin 150mg Injection and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Parentacin 150mg Injection therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Parentacin 150mg Injection is primarily metabolized by the liver. Therapy with Parentacin 150mg Injection should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
The liver is the primary site of Parentacin 150mg Injection metabolism. Patients with significantly impaired hepatic function may have a rise in the blood concentration of Parentacin 150mg Injection and a prolongation of the half-life. Additionally, the drug's usage may result in abnormal liver enzyme levels and jaundice. Patients with liver problems should receive Parentacin 150mg Injection therapy with caution. When given every 8 hours, dosage modifications might not be required. However, with high-dose therapy, serum concentrations should be observed, and during prolonged therapy, regular liver function tests should be carried out.
How to manage the interaction:
Parentacin 150mg Injection is primarily metabolized by the liver. Therapy with Parentacin 150mg Injection should be administered cautiously in patients with liver disease. Serum concentrations should be monitored during high-dose therapy, and periodic liver function tests should be performed during prolonged therapy.
CLINDAMYCIN-150MG/MLOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Parentacin 150mg Injection:
Parentacin 150mg Injection is partially removed by the kidney. Parentacin 150mg Injection should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Parentacin 150mg Injection concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Parentacin 150mg Injection should be administered cautiously in patients with severely impaired renal function. Serum Parentacin 150mg Injection concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Parentacin 150mg Injection is partially removed by the kidney. Parentacin 150mg Injection should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Parentacin 150mg Injection concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Parentacin 150mg Injection should be administered cautiously in patients with severely impaired renal function. Serum Parentacin 150mg Injection concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
CLINDAMYCIN-150MG/MLOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Parentacin 150mg Injection:
Parentacin 150mg Injection is partially removed by the kidney. Parentacin 150mg Injection should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Parentacin 150mg Injection concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Parentacin 150mg Injection should be administered cautiously in patients with severely impaired renal function. Serum Parentacin 150mg Injection concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
Parentacin 150mg Injection is partially removed by the kidney. Parentacin 150mg Injection should be used with caution in individuals with significantly impaired renal function. Dosage changes are probably to be required. Serum Parentacin 150mg Injection concentrations should be monitored throughout high-dose therapy, and renal function tests should be conducted on a regular basis during extended medication.
How to manage the interaction:
Therapy with Parentacin 150mg Injection should be administered cautiously in patients with severely impaired renal function. Serum Parentacin 150mg Injection concentrations should be monitored during high-dose therapy, and periodic renal function tests should be performed during prolonged therapy.
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