Parrel Plus Tablet 10's

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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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MRP ₹192.5

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₹28.9 Cashback (15%)

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Whats That

About Parrel Plus Tablet 10's

Parrel Plus Tablet 10's belongs to a group of medicines called ‘antidepressants’. It is used in the treatment of depression. Depression is a common mood disorder, which negatively affects a person's daily life described as feelings of sadness, loss, or anger. Depression symptoms can vary from mild to severe and can include: feeling sad, thoughts of death or suicide, loss of interest, weight loss or gain unrelated to dieting, trouble sleeping, loss of energy, feeling worthless or guilty and difficulty thinking.

Parrel Plus Tablet 10's is a combination of two drugs: clonazepam and paroxetine. Clonazepam increases levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine increases the serotonin hormone levels that improve mood, behaviour and prevent symptoms of depression.

You are advised to take Parrel Plus Tablet 10's for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Parrel Plus Tablet 10's for as long as your doctor has prescribed. Do not take Parrel Plus Tablet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Parrel Plus Tablet 10's causes drowsiness, sleepiness, do not drive unless you are alert. Parrel Plus Tablet 10's should not be given to children and adolescents aged 18 years for treating depression. Avoid consuming alcohol along with Parrel Plus Tablet 10's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Parrel Plus Tablet 10's

Depression

Directions for Use

Take Parrel Plus Tablet 10's with or without food. Parrel Plus Tablet 10's should be swallowed as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Parrel Plus Tablet 10's is a combination of two drugs: clonazepam and paroxetine. Clonazepam is a benzodiazepine, which works by increasing levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine is an antidepressant that increases the serotonin hormone levels that improve mood, behaviour, and prevent symptoms of depression.

Storage

Keep Parrel Plus Tablet 10's out of the sight and reach of children.

Side effects of Parrel Plus Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Dry Mouth

Here are the steps to Dry Mouth (xerostomia) caused by medication:

Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Do not take Parrel Plus Tablet 10's if you are allergic to Parrel Plus Tablet 10's or any other ingredients in it. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or pain medication. Talk to your doctor if you have a history of seizures, bipolar disorder, suicide attempts, or schizophrenia. Patients with liver diseases, diabetes, heart disease, lung disease and bleeding disorders should use Parrel Plus Tablet 10's with caution. Please do not stop the treatment abruptly as it can cause withdrawal reactions. Parrel Plus Tablet 10's is not recommended to use in children and adolescents under 18 years of age as it increases suicidal tendencies in this population. Consult your doctor immediately if you experience suicidal thoughts such as killing or harming yourself while on this medication. Do not take Parrel Plus Tablet 10's if you are pregnant or breastfeeding unless prescribed. Parrel Plus Tablet 10's causes drowsiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Parrel Plus Tablet 10's as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

ClonazepamSodium oxybate

Critical

ParoxetineFurazolidone

Critical

Drug-Drug Interactions

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ClonazepamSodium oxybate

Critical

How does the drug interact with Parrel Plus Tablet:
Taking Parrel Plus Tablet with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Parrel Plus Tablet and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

ParoxetineFurazolidone

Critical

How does the drug interact with Parrel Plus Tablet:
Taking Furazolidone with Parrel Plus Tablet can increase the risk of side effects

How to manage the interaction:
Taking Parrel Plus Tablet with Furazolidone is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

ParoxetineSelegiline

Critical

How does the drug interact with Parrel Plus Tablet:
When Parrel Plus Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Parrel Plus Tablet with Selegiline can possibly lead to an interaction but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

ParoxetineMetoclopramide

Critical

How does the drug interact with Parrel Plus Tablet:
Using Metoclopramide with Parrel Plus Tablet can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Metoclopramide with Parrel Plus Tablet is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.

ParoxetineProcarbazine

Critical

How does the drug interact with Parrel Plus Tablet:
Using procarbazine together with Parrel Plus Tablet can increase the risk of a serious condition called the serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Parrel Plus Tablet with Procarbazine is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

ParoxetineIsocarboxazid

Critical

How does the drug interact with Parrel Plus Tablet:
Using isocarboxazid with Parrel Plus Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Parrel Plus Tablet with Isocarboxazid is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

ParoxetineTranylcypromine

Critical

How does the drug interact with Parrel Plus Tablet:
Using tranylcypromine with Parrel Plus Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Parrel Plus Tablet with Tranylcypromine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

ParoxetineLinezolid

Critical

How does the drug interact with Parrel Plus Tablet:
Using Linezolid together with Parrel Plus Tablet can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Taking Parrel Plus Tablet with Linezolid is not recommended but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

ParoxetineEliglustat

Critical

How does the drug interact with Parrel Plus Tablet:
Coadministration of Parrel Plus Tablet with eliglustat can increase the risk of irregular heart rhythm

How to manage the interaction:
Although there is an interaction between Parrel Plus Tablet and Eliglustat, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.

ParoxetinePimozide

Critical

How does the drug interact with Parrel Plus Tablet:
Combining Parrel Plus Tablet with Pimozide can effect the rhythm of the heart

How to manage the interaction:
Taking Parrel Plus Tablet with Pimozide is not recommended, but should be taken if advised by a doctor. However, if you experience chest tightness, irregular heartbeat, blurred vision and nausea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Maintain a healthy and well-balanced diet.
Do not take stress as it may aggravate your condition.
Limit alcohol intake and quit smoking.
Engage in social activities frequently as it may improve self-esteem and confidence.
Limit caffeine intake.
Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
Regularly attend therapy sessions.
Perform meditation and yoga. This helps in relieving stress and provides relaxation.
Follow a regular sleep pattern to improve the amount and quality of sleep you get.
Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters.
Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Side Effects of Parrel Plus Tablet 10's

Nausea
Vomiting
Diarrhoea
Memory impairment
Uncoordinated body movements
Drowsiness
Low sexual desire and delayed ejaculation

Habit Forming

Yes

Therapeutic Class

ANTIDEPRESSANT

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Can I drive after taking Parrel Plus Tablet 10's?

Parrel Plus Tablet 10's causes sleepiness, drowsiness, and dizziness. Do not drive or operate machinery if you experience these symptoms after taking Parrel Plus Tablet 10's.

Does Parrel Plus Tablet 10's cause weight gain?

Parrel Plus Tablet 10's causes weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.

Can I stop taking Parrel Plus Tablet 10's if I feel well?

Do not discontinue Parrel Plus Tablet 10's without consulting your doctor as it could lead to recurring symptoms. To treat your condition effectually continue taking Parrel Plus Tablet 10's for as long as prescribed. Moreover, stopping this medicine suddenly may result in withdrawal symptoms. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Parrel Plus Tablet 10's.

Does Parrel Plus Tablet 10's cause sexual disturbances?

Parrel Plus Tablet 10's may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.

Does Parrel Plus Tablet 10's cause dry mouth?

Dry mouth could be a side-effect of Parrel Plus Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

What are the important warnings associated with Parrel Plus Tablet 10's?

Some patients experienced increased suicidal thoughts or actions in the first few months of the treatment with Parrel Plus Tablet 10's. Report to your doctor immediately if you notice any changes in your behaviour or mood while on this medication.

Drug-Drug Interactions Checker List

ASPIRIN
PREGABALIN
METOPROLOL
HYDROCODONE
QUETIAPINE
ALPRAZOLAM
CETIRIZINE
ARIPIPRAZOLE
ZOLPIDEM
LAMOTRIGINE
SERTRALINE

Special Advise

Parrel Plus Tablet 10's causes drowsiness. Avoid doing activities that require your complete focus and attention like driving when on this drug.
Abrupt stoppage of Parrel Plus Tablet 10's can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
Avoid consuming alcohol while on this medication as it can lead to dangerous side effects.
Parrel Plus Tablet 10's is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
To avoid getting addicted to this drug take it only in prescribed quantities and only as directed by your doctor. Do not self-medicate.

Disease/Condition Glossary

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drugs use, and medical conditions.