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  1. Home
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  3. Paxonil LS 12.5 mg Tablet 10's

Not for online sale
Paxonil LS 12.5 mg Tablet 10's, Pack of 10
Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

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Composition :

CLONAZEPAM-0.25MG + PAROXETINE-12.5MG

Manufacturer/Marketer :

Alteus Biogenics Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Paxonil LS 12.5 Tablet

Paxonil LS 12.5 Tablet belongs to a group of medicines called ‘antidepressants’. It is used in the treatment of depression. Depression is a common mood disorder, which negatively affects a person's daily life described as feelings of sadness, loss, or anger. Depression symptoms can vary from mild to severe and can include: feeling sad, thoughts of death or suicide, loss of interest, weight loss or gain unrelated to dieting, trouble sleeping, loss of energy, feeling worthless or guilty and difficulty thinking.

Paxonil LS 12.5 Tablet is a combination of two drugs: clonazepam and paroxetine. Clonazepam increases levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine increases the serotonin hormone levels that improve mood, behaviour and prevent symptoms of depression.

You are advised to take Paxonil LS 12.5 Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, memory impairment, uncoordinated body movements, drowsiness, low sexual desire and delayed ejaculation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Paxonil LS 12.5 Tablet for as long as your doctor has prescribed. Do not take Paxonil LS 12.5 Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Paxonil LS 12.5 Tablet causes drowsiness, sleepiness, do not drive unless you are alert. Paxonil LS 12.5 Tablet should not be given to children and adolescents aged 18 years for treating depression. Avoid consuming alcohol along with Paxonil LS 12.5 Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Paxonil LS 12.5 Tablet

Depression

Directions for Use

Take Paxonil LS 12.5 Tablet with or without food. Paxonil LS 12.5 Tablet should be swallowed as a whole with a glass of water; do not chew or crush it.

Medicinal Benefits

Paxonil LS 12.5 Tablet is a combination of two drugs: clonazepam and paroxetine. Clonazepam is a benzodiazepine, which works by increasing levels of a calming chemical, gamma-amino-butyric-acid (GABA), in your brain. Paroxetine is an antidepressant that increases the serotonin hormone levels that improve mood, behaviour, and prevent symptoms of depression.

Storage

Keep Paxonil LS 12.5 Tablet out of the sight and reach of children.

Drug Warnings

Do not take Paxonil LS 12.5 Tablet if you are allergic to Paxonil LS 12.5 Tablet or any other ingredients in it. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or pain medication. Talk to your doctor if you have a history of seizures, bipolar disorder, suicide attempts, or schizophrenia. Patients with liver diseases, diabetes, heart disease, lung disease and bleeding disorders should use Paxonil LS 12.5 Tablet with caution. Please do not stop the treatment abruptly as it can cause withdrawal reactions. Paxonil LS 12.5 Tablet is not recommended to use in children and adolescents under 18 years of age as it increases suicidal tendencies in this population. Consult your doctor immediately if you experience suicidal thoughts such as killing or harming yourself while on this medication. Do not take Paxonil LS 12.5 Tablet if you are pregnant or breastfeeding unless prescribed. Paxonil LS 12.5 Tablet causes drowsiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Paxonil LS 12.5 Tablet as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

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ParoxetineSelegiline
Critical
ParoxetinePhenelzine
Critical

Drug-Drug Interactions

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ParoxetineSelegiline
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
When Paxonil LS 12.5 mg Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Selegiline can possibly lead to an interaction but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, diarrhea, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
ParoxetinePhenelzine
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Using phenelzine with Paxonil LS 12.5 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Phenelzine is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineLinezolid
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Using Linezolid together with Paxonil LS 12.5 mg Tablet can increase the risk of a serious condition called serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is a chemical that plays a role in overall wellbeing and especially a mood stabilizer).

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Linezolid is not recommended but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineFurazolidone
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Taking Furazolidone with Paxonil LS 12.5 mg Tablet can increase the risk of side effects

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Furazolidone is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineThioridazine
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Coadministration of Paxonil LS 12.5 mg Tablet with Thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Thioridazine with Paxonil LS 12.5 mg Tablet is not recommended, but should be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetinePimozide
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Combining Paxonil LS 12.5 mg Tablet with Pimozide can effect the rhythm of the heart

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Pimozide is not recommended, but should be taken if advised by a doctor. However, if you experience chest tightness, irregular heartbeat, blurred vision and nausea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineProcarbazine
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Using procarbazine together with Paxonil LS 12.5 mg Tablet can increase the risk of a serious condition called the serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Procarbazine is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, or blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineTranylcypromine
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Using tranylcypromine with Paxonil LS 12.5 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Tranylcypromine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineIsocarboxazid
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Using isocarboxazid with Paxonil LS 12.5 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paxonil LS 12.5 mg Tablet with Isocarboxazid is not recommended, but should be taken if advised by a doctor. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ParoxetineMetoclopramide
Critical
How does the drug interact with Paxonil LS 12.5 mg Tablet:
Using Metoclopramide with Paxonil LS 12.5 mg Tablet can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Metoclopramide with Paxonil LS 12.5 mg Tablet is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy and well-balanced diet. 
  • Do not take stress as it may aggravate your condition.
  • Limit alcohol intake and quit smoking.
  • Engage in social activities frequently as it may improve self-esteem and confidence. 
  • Limit caffeine intake.
  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Side Effects of Paxonil LS 12.5 Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Memory impairment
  • Uncoordinated body movements
  • Drowsiness
  • Low sexual desire and delayed ejaculation

Habit Forming

Yes

Therapeutic Class

ANTIDEPRESSANT

Paxonil LS 12.5 Tablet Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Paxonil LS 12.5 Tablet causes sleepiness, drowsiness, and dizziness. Do not drive or operate machinery if you experience these symptoms after taking Paxonil LS 12.5 Tablet .

Paxonil LS 12.5 Tablet causes weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.

Do not discontinue Paxonil LS 12.5 Tablet without consulting your doctor as it could lead to recurring symptoms. To treat your condition effectually continue taking Paxonil LS 12.5 Tablet for as long as prescribed. Moreover, stopping this medicine suddenly may result in withdrawal symptoms. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Paxonil LS 12.5 Tablet .

Paxonil LS 12.5 Tablet may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth could be a side-effect of Paxonil LS 12.5 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Some patients experienced increased suicidal thoughts or actions in the first few months of the treatment with Paxonil LS 12.5 Tablet . Report to your doctor immediately if you notice any changes in your behaviour or mood while on this medication.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PREGABALIN
  • METOPROLOL
  • HYDROCODONE
  • QUETIAPINE
  • ALPRAZOLAM
  • CETIRIZINE
  • ARIPIPRAZOLE
  • ZOLPIDEM
  • LAMOTRIGINE
  • SERTRALINE

Special Advise

  • Paxonil LS 12.5 Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention like driving when on this drug.
  • Abrupt stoppage of Paxonil LS 12.5 Tablet can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on this medication as it can lead to dangerous side effects.
  • Paxonil LS 12.5 Tablet is unsafe for usage if you're pregnant or are planning to get pregnant. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
  • To avoid getting addicted to this drug take it only in prescribed quantities and only as directed by your doctor. Do not self-medicate.

Disease/Condition Glossary

Depression: It is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drugs use, and medical conditions.

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