Pazobrite 400 mg Tablet 30's

Pazobrite 400 mg Tablet 30's belongs to the group of medicine called ‘anti-cancer’ that is primarily indicated in the treatment of kidney and soft tissue cancer.  Kidney cancer also known as renal cancer is a disease in which healthy cells of the kidney become malignant (cancerous), grow in an uncontrolled manner and forms a tumor. When a group of cancer occurs in different parts of the body such as bones, muscles, deep layers of skin, and fat then it is known as soft tissue sarcomas. This type of cancer may also form in nerves, blood vessels or connective tissues that support organs of the body.

Pazobrite 400 mg Tablet 30's contains 'Pazopanib' which falls in the category of medicines known as 'kinase inhibitors'. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Pazobrite 400 mg Tablet 30's as prescribed by your doctor. You are suggested to take Pazobrite 400 mg Tablet 30's as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side effects such as itching or skin rash, acne, dry skin, vomiting, diarrhea and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Pazobrite 400 mg Tablet 30's for as long as your doctor has prescribed. Do not take Pazobrite 400 mg Tablet 30's if you are pregnant or planning for pregnancy as Pazobrite 400 mg Tablet 30's causes serious birth defects. Pazobrite 400 mg Tablet 30's should not be taken by breastfeeding mothers as it passes into breast milk and may cause possible risk to the infant. Elderly people are more sensitive to medicine so the doctor may adjust the dosage according to the condition. Avoid consuming alcohol along with Pazobrite 400 mg Tablet 30's as it could lead to increased dizziness.

Pazobrite 400 mg Tablet 30's is a ' tyrosine kinase inhibitor (TKI)', that stops the uncontrolled growth and spread of cancerous cells. Pazobrite 400 mg Tablet 30's is effective in treating thyroid, liver and kidney cancer. It acts by stopping the action of the abnormal protein that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed it undergoes a usual process of maturity. Cancerous cells form new cells more quickly so Pazobrite 400 mg Tablet 30's targets cancerous cells and blocks the action of Tyrosine kinases enzymes (responsible for causing cancer). It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Pazobrite 400 mg Tablet 30's stops the production, spread and growth of cancerous cells in the body.

• Acne
• Dry skin
• Nausea
• Vomiting
• Diarrhea
• Loss of appetite
• Itching or skin rash

Pazobrite 400 mg Tablet 30's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side-effects. Before your doctor prescribes you Pazobrite 400 mg Tablet 30's, tell them if you have heart problems, high blood pressure, bleeding issues, surgery or an electrolyte imbalance (like abnormal levels of magnesium, calcium  or potassium in the blood). Pazobrite 400 mg Tablet 30's is restricted to use in persons who are sensitive to any of its constituents or have squamous cell lung cancer or already taking carboplatin and paclitaxel.

Drug-Drug Interaction: Pazobrite 400 mg Tablet 30's may have interaction with anti-cancer medicine (Sorafenib and Paclitaxel), antibiotics (Neomycin), anti-seizure medicine (carbamazepine, phenytoin), an antacid  (Omeprazole).

Drug-Food Interaction: The absorption of Pazobrite 400 mg Tablet 30's gets reduced in presence of food. This is why it is suggested to take Pazobrite 400 mg Tablet 30's on an empty stomach or 1 or 2 hours after a meal. Additionally, an individual should avoid grapefruit juice as it may increase the amount of drug in the bloodstream.

Drug-Disease Interaction: Do not take Pazobrite 400 mg Tablet 30's if you have squamous cell lung cancer. 

• CARBAMAZEPINE
• PACLITAXEL
• OMEPRAZOLE
• NEOMYCIN
• SORAFENIB
• PHENYTOIN

• Physical activity helps in strengthening muscles reduce fatigue, helps in weight loss and give strength. Gentle activities like 20-30minutes of walking or swimming would be helpful.
• Performing yoga and other relaxation techniques may also help in improving physical and mental health and may reduce your stress levels.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep as resting helps in improving your health, mental ability, and improves attention.
• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing fiber help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
• Avoid smoking and alcohol consumption.

• Seek medical attention immediately you have swelling in your lower legs, fast heartbeats, or trouble breathing. It may be a sign of a heart problem.
• Pazobrite 400 mg Tablet 30's may cause bleeding so tell your doctor if you see blood in urine or stools.

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer, namely benign (localized) and metastatic (spread to the whole body). There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer, etc. Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation and stem cell therapy.

Renal cancer: Kidneys help to get rid of waste by filtering blood, regulate fluid balance, and helps in making urine. Kidney cancer occurs when cancerous cells start growing uncontrollably in the kidneys.

Soft tissue sarcoma: It is a disease in which cancerous cells form in the soft tissues of the body such as a deep layer of skin, fat, muscles and bones. This type of cancer can also form in nerves, blood vessels or tissues that support organs of the body. This type of cancer is most common in the neck, arms, legs, abdomen and legs.