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Written By ,
Reviewed By Sunny S , MBBS

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Consume Type :

Oral

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About Pazom DSR Capsule

Pazom DSR Capsule belongs to a class of medications known as 'dopamine antagonist' used to treat nausea (feeling sick) and vomit (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying).

Pazom DSR Capsule contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take Pazom DSR Capsule as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking Pazom DSR Capsule . However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take Pazom DSR Capsule for longer than seven days. The most common side effect of Pazom DSR Capsule is dry mouth. This side effect is temporary and may resolve after some time; however, if this side persists, contact the doctor.

Do not consume Pazom DSR Capsule if you are hypersensitive to any components present in Pazom DSR Capsule . Before taking the Pazom DSR Capsule , inform your doctor if you suffer from liver or kidney problems. Prolonged intake of Pazom DSR Capsule may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Pazom DSR Capsule is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Pazom DSR Capsule .

Uses of Pazom DSR Capsule

Nausea, Vomiting.

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Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it. Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole. Oral Suspension/Syrup/Oral drops: Shake the bottle well before use. Check the label for directions and take Pazom DSR Capsule in doses as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack.

Key Benefits

Pazom DSR Capsule contains domperidone, a dopamine antagonist that helps by blocking certain vomiting-inducing receptors in the brain. Pazom DSR Capsule also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pazom DSR Capsule
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Drug Warnings

Do not consume Pazom DSR Capsule if you are allergic to any components present in Pazom DSR Capsule . Before taking the Pazom DSR Capsule , contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of Pazom DSR Capsule may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the Pazom DSR Capsule , immediately contact your doctor. Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the Pazom DSR Capsule .

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Pazom DSR Capsule:
Co-administration of Rilpivirine is taken with Pazom DSR Capsule, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Pazom DSR Capsule with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pazom DSR Capsule:
Taking Pazom DSR Capsule with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Pazom DSR Capsule and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Pazom DSR Capsule:
Co-administration of Pazom DSR Capsule reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Pazom DSR Capsule with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pazom DSR Capsule:
Taking Dasatinib with Pazom DSR Capsule may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Pazom DSR Capsule with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pazom DSR Capsule:
Co-administration of Methotrexate with Pazom DSR Capsule can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Pazom DSR Capsule and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Pazom DSR Capsule:
Taking Pazom DSR Capsule can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Pazom DSR Capsule with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleNelfinavir
Severe
How does the drug interact with Pazom DSR Capsule:
Taking Nelfinavir with Pazom DSR Capsule may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Pazom DSR Capsule with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pazom DSR Capsule:
Taking Erlotinib with Pazom DSR Capsule may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Pazom DSR Capsule with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pazom DSR Capsule:
Taking Gefitinib with Pazom DSR Capsule reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Pazom DSR Capsule with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Pazom DSR Capsule to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Pazom DSR Capsule:
Coadministration of Pazom DSR Capsule with Cisapride can increase the blood levels of Pazom DSR Capsule.

How to manage the interaction:
There may be a possibility of interaction between Pazom DSR Capsule and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Include more cool beverages in your food like clear soups, flavoured gelatin, and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink after or any other liquid at least 30 minutes after eating food. After eating food, lie down for at least after 2 hours.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

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Alcohol

Safe if prescribed

Drinking alcohol with Pazom DSR Capsule may cause sleepiness, or an irregular heartbeat.

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Pregnancy

Consult your doctor

Pazom DSR Capsule is not usually recommended in pregnancy.

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Breast Feeding

Consult your doctor

Pazom DSR Capsule is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

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Driving

Safe if prescribed

Pazom DSR Capsule has no effect on your ability to drive or operate machinery.

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Liver

Consult your doctor

Pazom DSR Capsule should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Kidney

Consult your doctor

Pazom DSR Capsule should be taken with caution in patients with kidney problems. Your doctor will adjust your dose depending upon the condition of your disease.

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Children

Safe if prescribed

Pazom DSR Capsule should not be given to adolescents younger than 12 years of age or are less than 35 kg in weight.

FAQs

Pazom DSR Capsule contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

If you are intolerant to sugars, please inform your doctor before starting Pazom DSR Capsule as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.

Yes, Pazom DSR Capsule can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.

If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.

Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.

No, it is a prescribed medication; it should be used only if specified by the doctor.

Country of origin

India

Manufacturer/Marketer address

S No. 259, P No. 4, Kalwadi Wasti Vishrantwadi Pune Pune MH 411032 IN
Other Info - PAZ0033

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