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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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About Pegawin Tablet

Pegawin Tablet is a combination of medicine that belongs to the class of medications called 'anticonvulsant' used for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms of neuropathic pain include shooting, burning pain followed by tingling and numbness (loss of sensation). Neuropathic pain can be caused due to amputation of limbs, diabetic neuropathy (nerve damage due to excess blood sugar level), excessive alcohol intake (alcoholism) and cancer treatment via chemotherapy.

Pegawin Tablet is a combination of five drugs: Pregabalin (anticonvulsant), Methylcobalamin (vitamin B12), Benfotiamine (vitamin B1), Pyridoxine (vitamin B6) and Folic acid (vitamin B9). Pregabalin affects the chemicals in the brain that send pain signals to the nervous system thereby relieving nerve pain and lowers the risk of seizures (fits). Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Benfotiamine and Folic acid help in delivering essential nutrients to the nerves. Together, Pegawin Tablet provides relief from neuropathic pain.

Take Pegawin Tablet as prescribed. Your doctor will advise you on how often you take Pegawin Tablet based on your medical condition. A person taking Pegawin Tablet might experience side effects like dizziness, sleepiness, tiredness, nausea and vomiting. Although, not every person faces the side effects of Pegawin Tablet  and even some of the unpleasant effects of Pegawin Tablet do not require medical attention. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Pegawin Tablet for as long as your doctor has prescribed. Please do not stop taking Pegawin Tablet without consulting your doctor as it could cause withdrawal symptoms. Do not take Pegawin Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Pegawin Tablet causes drowsiness and dizziness, so drive only if you are alert. Pegawin Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pegawin Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Pegawin Tablet

Neuropathic pain

Directions for Use

Take Pegawin Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

Pegawin Tablet is a combination of five drugs: Pregabalin (anti-convulsant or antiepileptic), methylcobalamin (vitamin B12), benfotiamine (vitamin B1), pyridoxine (vitamin B6) and folic acid (vitamin B9). Pegawin Tablet is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals in the nervous system, thereby relieving nerve pain and lowers the risk of seizures. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Benfotiamine and Folic acid help in providing essential nutrients to the nerves. Together, Pegawin Tablet helps in providing relief from neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Pegawin Tablet if you are allergic to any of its contents. Inform your doctor before taking Pegawin Tablet if you have or had heart problems or bipolar syndrome. Please do not stop taking Pegawin Tablet without consulting your doctor as it could cause withdrawal symptoms. Do not take Pegawin Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Pegawin Tablet may affect a person's ability to drive. So, avoid driving or operating any machine. Pegawin Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pegawin Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects. Pegawin Tablet can cause life-threatening breathing problems in patients with COPD and asthma. So a person with long paused breathing, blue-colored lips, or sleeping disorder should inform the doctor before use of Pegawin Tablet .

Drug-Drug Interactions

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PregabalinHydromorphone
Severe
PregabalinPethidine
Severe

Drug-Drug Interactions

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PregabalinHydromorphone
Severe
How does the drug interact with Pegawin Tablet:
Using Pegawin Tablet together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Pegawin Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pegawin Tablet:
Using Pegawin Tablet together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pegawin Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pegawin Tablet:
Using Pegawin Tablet together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pegawin Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pegawin Tablet:
Using Tapentadol together with Pegawin Tablet may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Pegawin Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinSodium oxybate
Severe
How does the drug interact with Pegawin Tablet:
Using Sodium oxybate together with Pegawin Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Pegawin Tablet with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
PregabalinAlfentanil
Severe
How does the drug interact with Pegawin Tablet:
Using Pegawin Tablet together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Pegawin Tablet and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pegawin Tablet:
Using Pegawin Tablet together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pegawin Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinCodeine
Severe
How does the drug interact with Pegawin Tablet:
Using Pegawin Tablet together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Pegawin Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pegawin Tablet:
When Tramadol is used with Pegawin Tablet, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Although taking tramadol and Pegawin Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Pegawin Tablet:
Using Pegawin Tablet together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pegawin Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • GABAPENTIN
  • PHENOBARBITAL
  • PHENYTOIN
  • AMITRIPTYLINE
  • DULOXETINE
  • MIRTAZAPINE
  • FLUOXETINE
  • SERTRALINE
  • CODEINE
  • FENTANYL
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • DIAZEPAM
  • ALPRAZOLAM
  • METFORMIN
  • METHOTREXATE
  • SULFASALAZINE
  • NEOMYCIN
  • CHLORAMPHENICOL
  • LEVODOPA

Special Advise

  • Pegawin Tablet contains Pregabalin, prolonged intake of pregabalin may lead to mental or physical dependence. Keep your doctor informed about your health condition.
  • Pegawin Tablet may rarely have serious side effects like suicidal thoughts, consult your doctor immediately if you face any such side effects.
  • Your doctor may advice you to maintain a healthy diet as Pegawin Tablet may cause weight gain.

Disease/Condition Glossary

Neuropathic pain: It is a nervous disorder that occurs due to nerve damage caused by chronic progressive nerve disease, limb amputation, diabetes or due to infection or injury. The pain could be intermittent or continuous, felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of senses is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain that is not triggered by an injury, the body sends the pain signals. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).

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