Pegihep 100 Injection 1's

Pegihep 100 Injection is in a class of medications called interferons. It can be used alone or in combination with other medications to treat chronic (long-term) hepatitis C infection (swelling of the liver caused by a virus) in people who show signs of liver damage and who have not been treated with interferon-alpha (a medication similar to peginterferon alfa-2b) in the past.

Pegihep 100 Injection contains Peginterferon alpha-2b works by decreasing the amount of hepatitis C virus (HCV) in the body. 

In some cases, Pegihep 100 Injection may cause side effects such as injection site reactions, breathing problems (including shortness of breath), feeling depressed, trouble sleeping, thinking, or concentrating, dizziness, severe stomach pain or cramps, fever or chills and painful or inflamed muscles (sometimes severe). Pegihep 100 Injection can induce or worsen serious or fatal conditions like infections, mental illness, mood and behaviour issues, or thoughts of hurting or killing oneself or others. You are advised to talk to your doctor if any of the side effects persist or worsen.

Extreme caution should be exercised while using Pegihep 100 Injection in patients with leukopenia, thrombocytopenia, renal Insufficiency and depression. So, inform your doctor about all your medical conditions. Also, let your doctor know about all medications you are taking to rule out the potential interactions and adverse events. Pegihep 100 Injection should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. It is unknown whether the components of this medicinal product are excreted in human milk. Breast-feeding should be stopped before starting treatment. Dosage is determined by body surface area and body weight in children three years of age and older and adolescent patients.

Pegihep 100 Injection contains Interferon beta-1A, which belongs to the class of medications called interferons. It can be used alone or in combination with other medications to treat chronic (long-term) hepatitis C infection (swelling of the liver caused by a virus) in people who show signs of liver damage and who have not been treated with interferon-alpha (a medication similar to peginterferon alfa-2b) in the past. It works by modulating the body's immune system.

Pegihep 100 Injection cause or worsen serious or fatal autoimmune, ischemic, neuropsychiatric, and infectious illnesses. Patients with these diseases should be examined on a regular basis by clinical and laboratory testing, and they should discontinue taking Pegihep 100 Injection. Many, but not all, of these issues are resolved once the PEG-Intron medicine is stopped.

Only a physician with experience managing hepatitis C patients should initiate and monitor treatment.

Pregnancy must be avoided at all costs in female patients or partners of male patients taking Pegihep 100 Injection in combination with ribavirin. Females of childbearing potential must use an effective contraceptive during treatment and four months after treatment. Male patients or their female partners must use an effective contraceptive during treatment and for seven months after treatment is completed.

The use of Pegihep 100 Injection in children and adolescents with serious psychiatric problems is not advised.

Patients having a history of depression and/or suicide attempts should be closely monitored.

Use of Pegihep 100 Injection is contraindicated in populations with hypersensitivity to the active substance, to any interferon, or to any of the excipients present in Pegihep 100 Injection.

Let your doctor know if you have a history of severe pre-existing cardiac disease, including unstable or uncontrolled cardiac disease in the previous six months, severe, debilitating medical conditions, autoimmune hepatitis or a history of autoimmune disease, severe hepatic dysfunction or decompensated cirrhosis of the liver, pre-existing thyroid disease unless it can be controlled with conventional treatment, epilepsy and/or compromised central nervous system (CNS) function and HCV/HIV patients with cirrhosis and a Child-Pugh score ≥ 6.

• Avoid heavily processed foods and saturated fats.
• Include fruits, vegetables, and whole grains in the diet.
• Try to stay active. Choose moderate exercises.
• Quit smoking.
• Prevent stress by doing meditation or yoga.

• Injection site reactions
• Breathing problems (including shortness of breath)
• Feeling depressed
• Trouble sleeping
• Thinking or concentrating
• Dizziness
• Severe stomach pain or cramps
• Fever or chills
• Painful or inflamed muscles (sometimes severe)

• Patients receiving Pegihep 100 Injection therapy should have haematological and blood chemistry testing before beginning treatment and then on a regular basis thereafter.
• Pegihep 100 Injection, alone or in combination with ribavirin, may result in significant reductions in neutrophil and platelet counts, as well as hematologic, endocrine (e.g., TSH), and hepatic problems.

Hepatitis C refers to the inflammation of the liver due to the hepatitis C virus (HCV). This virus can cause lifelong serious illnesses like cancer and cirrhosis (scarring of the liver). It can be both chronic and acute. Acute hepatitis C is a short-term infection with symptoms lasting up to 6 months. Chronic hepatitis C is a long-term infection that can last an entire life and lead to serious health issues if left untreated.

The majority of those suffering from hepatitis C don’t show any symptoms. However, some experience symptoms within 1 to 3 months of exposure to the virus. The symptoms may be fatigue, dark yellow urine, fever, joint pain, clay- or grey-coloured stool, loss of appetite, pain in the abdomen, vomiting or/and nausea and jaundice. Those suffering from chronic hepatitis C often don't have any symptoms until complications arise, which can happen years after exposure to HCV. Consequently, screening for this illness is essential despite having no symptoms.