Perampil 4mg Tablet 15's

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

Prescription drug

MRP ₹223

(Inclusive of all Taxes)

₹33.5 Cashback (15%)

Provide Delivery Location

Non returnable*

Know More

COD available

Online payment accepted

Prescription drug

Whats That

About Perampil 4mg Tablet

Perampil 4mg Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading unconscious state.

Perampil 4mg Tablet contains 'Perampanel'. It prevents seizures or epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the brain's abnormal and excessive activity of the nerve cells.

In some cases, Perampil 4mg Tablet may cause common side effects such as dizziness, drowsiness, increased or decreased appetite, weight gain, fatigue, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Perampil 4mg Tablet is not recommended during pregnancy and in children below four years. Consult your doctor if you are breastfeeding. Perampil 4mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Perampil 4mg Tablet as it could lead to increased dizziness and drowsiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Perampil 4mg Tablet

Epilepsy/seizures

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Perampil 4mg Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Perampil 4mg Tablet contains perampanel. It is used to treat epilepsy. Perampil 4mg Tablet prevents seizures or epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.

Storage

Keep Perampil 4mg Tablet out of the sight and reach of children.

Side effects of Perampil 4mg Tablet

Dizziness Or Spinning Sensation

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drowsiness

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Difficulty Walking

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Irritability

Manage stress by practising deep breathing, yoga or meditation.
Get enough sleep. Maintain a regular sleep cycle.
Exercise regularly. Try physical activities like walking, running, or dancing.
Limit stimulants like tea, coffee and alcohol.
Identify triggers and try managing them.
Take a break by scheduling time for yourself.
Try creative activities like writing, dancing or painting as it helps release tension.

Uncoordinated Muscle Movements

Uncoordinated muscle movements need immediate medical attention.
Observe your movements and try to understand and control the particular movement.
Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
Implement massage techniques to enhance blood flow to organs.
Take a balanced diet and quit smoking.
Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.

Burning Or Tingling Sensation

Change positions or take a break from activity to relieve symptoms.
Avoid postures that put a lot of pressure on just one area of the body.
If you have vitamin deficiency, take supplements or change your diet.
Exercise regularly like cycling, walking or swimming.
Avoid sitting with your legs crossed.
Clench and unclench your fists and wiggle your toes.
Massage the affected area.

Drug Warnings

Do not take Perampil 4mg Tablet if you are allergic to any of its contents. Inform your doctor before taking Perampil 4mg Tablet if you have serious liver problems, moderate or severe kidney problems, alcoholism, or drug dependence. Perampil 4mg Tablet is not recommended during pregnancy and in children below 4 years. Consult your doctor if you are breastfeeding. Perampil 4mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Perampil 4mg Tablet as it could lead to increased dizziness and drowsiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

PerampanelBuprenorphine

Severe

PerampanelEsketamine

Severe

Drug-Drug Interactions

Login/Sign Up

PerampanelBuprenorphine

Severe

How does the drug interact with Perampil 4mg Tablet:
When buprenorphine is used with Perampil 4mg Tablet, it may lead to significant adverse effects.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Perampil 4mg Tablet can result in an interaction, it can be taken if a doctor has advised it. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Consult a doctor if you have any questions or concerns. Do not discontinue any medications without consulting a doctor.

PerampanelEsketamine

Severe

How does the drug interact with Perampil 4mg Tablet:
Co-administration of Perampil 4mg Tablet with esketamine can increase the risk of side effects of Perampil 4mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Perampil 4mg Tablet and Esketamine, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

PerampanelKetamine

Severe

How does the drug interact with Perampil 4mg Tablet:
Using ketamine together with Perampil 4mg Tablet may increase side effects such as dizziness, drowsiness, confusion and difficulty concentrating.

How to manage the interaction:
Although there is a possible interaction between Perampil 4mg Tablet and Ketamine, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

PerampanelSodium oxybate

Severe

How does the drug interact with Perampil 4mg Tablet:
Using sodium oxybate together with Perampil 4mg Tablet may increase side effects such as dizziness, drowsiness, confusion, difficulty concentrating

How to manage the interaction:
Although taking Perampil 4mg Tablet and Sodium oxybate together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
Exercising regularly helps in maintaining weight and improving overall health.
Rest well, and get plenty of sleep.
Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
Understand what triggers seizures and try reducing or avoiding them.
Please pay attention to overall health, as it can help reduce seizure activity.
Have a seizure response plan, and help those around you know what to do.
Install an alarm or emergency device to get assistance during a seizure attack.
A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for the generation of energy.
Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
Avoid smoking and alcohol consumption.

Side Effects of Perampil 4mg Tablet

Dizziness
Drowsiness or sleepiness
Increased or decreased appetite
Weight gain
Feeling aggressive, angry, irritable, anxious or confused
Fatigue
Nausea

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Perampil 4mg Tablet Substitute

Fytonil 4 Tablet 15's

by Others

₹9.90per tablet

Hetram 4Mg Tab 10'S

by Others

₹12.60per tablet

Addperam 4 Tablet 10's

by Others

₹13.32per tablet

Ampanel 4 Tablet 10's

by Others

₹14.58per tablet

Peramnel 4 Tablet 10's

by Others

₹14.58per tablet

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:40 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

How does Perampil 4mg Tablet work?

Perampil 4mg Tablet prevents seizures by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.

Does Perampil 4mg Tablet cause weight gain?

Perampil 4mg Tablet may cause weight gain, so try to maintain a proper weight by following a healthy diet and exercising regularly.

Can I stop taking Perampil 4mg Tablet if I feel well?

Do not discontinue Perampil 4mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Perampil 4mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Perampil 4mg Tablet ; your doctor will reduce the dose gradually to avoid precipitating seizures.

Is it safe to conceive while on treatment with Perampil 4mg Tablet ?

Avoid conceiving while on treatment with Perampil 4mg Tablet as it is not recommended for use during pregnancy. Use a reliable method of contraception during treatment with Perampil 4mg Tablet and for one month after the last dose of Perampil 4mg Tablet .

Does Perampil 4mg Tablet affect contraceptives?

Perampil 4mg Tablet might make certain hormonal contraceptives, such as levonorgestrel less effective, affecting contraception. Therefore, you are advised to use other forms of contraception such as coil or condom while on treatment with Perampil 4mg Tablet . Discuss with your doctor if you have any concerns.

Drug-Drug Interactions Checker List

ESLICARBAZEPINE ACETATE
RUFINAMIDE
CLOBAZAM
TOPIRAMATE
BACLOFEN

Special Advise

Close monitoring of lipid profile is recommended during treatment with Perampil 4mg Tablet .
Consult your doctor immediately if you experience suicidal tendencies.

Disease/Condition Glossary

Epilepsy: It is a neurological/central nervous system disorder in which the brain's electrical pattern is disrupted by sudden electrical impulses that affect an individual’s consciousness, movements, or sensations. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.