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  3. Perinorm Tablet 10's

Perinorm Tablet 10's, Pack of 10 TABLETS
Perinorm Tablet 10's, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Composition :

METOCLOPRAMIDE-10MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Perinorm Tablet

Perinorm Tablet belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and which might occur after migraine. Additionally, Perinorm Tablet is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus.

Perinorm Tablet contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

In some cases, Perinorm Tablet may cause common side-effects such as restlessness, fatigue, drowsiness, diarrhoea, weakness, and lassitude (lack of energy). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Perinorm Tablet for more than 3 months as it might increase the risk of tardive dyskinesia (movement disorder). Consult your doctor before taking Perinorm Tablet if you are pregnant or breastfeeding. Perinorm Tablet may cause drowsiness and dizziness, so avoid driving until you know how Perinorm Tablet affects you. Avoid consuming alcohol along with Perinorm Tablet as it could lead to increased drowsiness. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Perinorm Tablet

Nausea, vomiting, gastroesophageal reflux disease (GERD), and diabetic gastroparesis (delayed gastric emptying in people with diabetes).

Directions for Use

Take Perinorm Tablet 30 minutes before food, preferably at bedtime or as advised by the doctor. Tablet/Capsule: Swallow it as a whole with water; do not chew or break the tablet/capsule. Orally disintegrating tablet (ODT): Place the tablet on top of the tongue and allow it to dissolve. Do not handle the ODT with wet hands.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the bottle well before each use.

Medicinal Benefits

Perinorm Tablet belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and which might occur after migraine. Additionally, Perinorm Tablet is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus. Perinorm Tablet contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also affects the dopamine receptor in the brain and gut, thereby helps in preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight
Side effects of Perinorm Tablet
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Drug Warnings

Do not take Perinorm Tablet if you are allergic to any of its contents; if you have bleeding or obstruction in the stomach, tardive dyskinesia (movement disorder), pheochromocytoma (tumour in the adrenal glands), or epilepsy. Talk to your doctor before taking Perinorm Tablet if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, liver or kidney problems, Parkinson’s disease, methaemoglobinaemia; if you are taking levodopa or if you have gastrointestinal surgery in the last 3-4days. Do not take Perinorm Tablet for more than three months as it might increase the risk of tardive dyskinesia; the risk increases if you are older, especially if you are an older woman or if you have diabetes. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions

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MetoclopramideVenlafaxine
Critical
MetoclopramideLurasidone
Critical

Drug-Drug Interactions

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MetoclopramideVenlafaxine
Critical
How does the drug interact with Perinorm Tablet:
Coadministration of Perinorm Tablet with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Perinorm Tablet with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideLurasidone
Critical
How does the drug interact with Perinorm Tablet:
The combination of Lurasidone and Perinorm Tablet may result in significantly increased Lurasidone blood levels. This may raise the possibility of undesirable consequences such as Parkinson's disease. (It is a neurological condition that causes uncontrollable movements)and Tardive dyskinesia (uncontrollable movements, particularly of the lower face).

How to manage the interaction:
Lurasidone and Perinorm Tablet is not recommended, as they may interact, but can be used if a doctor prescribes them. Consult a doctor if you have muscle spasms, or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning, tongue thrusting, teeth clenching, jaw twitching, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without visiting a doctor.
MetoclopramideTetrabenazine
Critical
How does the drug interact with Perinorm Tablet:
Coadministration of Tetrabenazine and Perinorm Tablet can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Tetrabenazine and Perinorm Tablet together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoclopramideProchlorperazine
Critical
How does the drug interact with Perinorm Tablet:
Coadministration of Perinorm Tablet and prochlorperazine can increase the risk of side effects.

How to manage the interaction:
Taking Perinorm Tablet with Prochlorperazine together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
MetoclopramideNefazodone
Critical
How does the drug interact with Perinorm Tablet:
Coadministration of Perinorm Tablet with Nefazodone can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Perinorm Tablet with Nefazodone is generally avoided as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.
MetoclopramideAripiprazole
Critical
How does the drug interact with Perinorm Tablet:
Co-administration of Perinorm Tablet with Aripiprazole can increase the risk of side effects.

How to manage the interaction:
Taking Aripiprazole with Perinorm Tablet is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideMethyldopa
Critical
How does the drug interact with Perinorm Tablet:
Taking Methyldopa and Perinorm Tablet together can decrease the levels and effects of Methyldopa.

How to manage the interaction:
Taking Perinorm Tablet with Methyldopa is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MetoclopramideDuloxetine
Critical
How does the drug interact with Perinorm Tablet:
Coadministration of Perinorm Tablet with duloxetine increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Perinorm Tablet with Duloxetine is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
MetoclopramideCitalopram
Critical
How does the drug interact with Perinorm Tablet:
Coadministration of Citalopram with Perinorm Tablet can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Citalopram with Perinorm Tablet is generally avoided as it can possibly result in an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
MetoclopramideZiprasidone
Critical
How does the drug interact with Perinorm Tablet:
Taking Perinorm Tablet with Ziprasidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Perinorm Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience lip-smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:31 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Perinorm Tablet works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Take Perinorm Tablet only for as long as the doctor has prescribed it for you. Do not take Perinorm Tablet for more than three months as it might increase the risk of tardive dyskinesia (movement disorder), which is often irreversible. The risk of developing tardive dyskinesia increases with the total dosage and duration of treatment.

Diarrhoea might be a side-effect of Perinorm Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if the condition persists or worsens.

Maintain a minimum gap of 6 hours between each dose. Do not take another dose of Perinorm Tablet even in case of vomiting and rejection of dose to avoid an overdose.

Perinorm Tablet may cause uncontrollable movements such as shaking, tics, twisting movements, muscle stiffness and rigidity. Consult your doctor if you experience these symptoms.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ACETAMINOPHEN
  • DULOXETINE
  • DIPHENHYDRAMINE
  • ALPRAZOLAM
  • PREGABALIN
  • LEVODOPA

Special Advise

Your doctor may advise you to regularly get blood tests done to check your blood pigment levels. If Methaemoglobinaemia is observed, treatment with Perinorm Tablet should be stopped immediately and permanently. Methaemoglobinaemia is a blood condition in which the haemoglobin iron is in the oxidized state and cannot reversibly bind to oxygen.

Disease/Condition Glossary

Nausea/Vomiting: Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the contents of the stomach through the mouth. Nausea and vomiting may occur separately or together. The common causes include motion sickness, emotional stress, indigestion, food poisoning, high fever or overeating. Nausea/vomiting might also occur as an unpleasant effect of therapy, such as chemotherapy and radiation therapy. 

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

Diabetic gastroparesis: Diabetic gastroparesis is delayed gastric emptying in people with diabetes. Gastroparesis, also called delayed gastric emptying is a condition that occurs when the stomach takes too long to empty the food into the intestine. Symptoms include nausea, vomiting, indigestion, loss of appetite, bloating and heartburn.

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