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Whats That
About Pernex-Plus Gel
Pernex-Plus Gel belongs to the class of dermatological preparations called ‘antiacne’ used to treat acne (pimples) and remove the skin's upper dead layer. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin) causing redness and swelling.
Pernex-Plus Gel is a combination of two drugs: Adapalene (retinoids) and Benzoyl peroxide (keratolytic agent). Adapalene belongs to the retinoid class (human-made vitamin A) which works by loosening the cells on the skin’s surface and unblocks pores by reducing oil production in the skin. Thereby, decreases pimples, whiteheads, and blackheads. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that cause acne.
Take Pernex-Plus Gel as prescribed. Pernex-Plus Gel is only for external use. Avoid contact of Pernex-Plus Gel with nose, ears, mouth, or eyes. In case Pernex-Plus Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Your doctor will advise you how often you take Pernex-Plus Gel based on your medical condition. You may experience dry skin, scaling, local skin rash, irritation, redness, or burning sensation of the skin in some cases. Most of these side effects of Pernex-Plus Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to Pernex-Plus Gel or any other medicines, please tell your doctor. Do not apply Pernex-Plus Gel on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Avoid exposure to tanning beds or sunlight while using Pernex-Plus Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Pernex-Plus Gel. Do not apply Pernex-Plus Gel in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as irritation, scaling, or redness of the skin. If you have eczema (itchy, swollen, rough, and cracked skin) or sunburned skin, please inform your doctor before taking Pernex-Plus Gel.
Uses of Pernex-Plus Gel
Directions for Use
Key Benefits
Pernex-Plus Gel is a combination of two drugs: Adapalene and Benzoyl peroxide used to treat acne (pimples). Adapalene is a retinoid (human-made vitamin A) that loosens the cells on the skin’s surface and unblocks pores by reducing oil production in the skin. Thereby, decreases pimples, spots, whiteheads, and blackheads. Also, it increases the production of new skin cells and helps in natural exfoliation (removal of dead skin cells) of the outer layers of the skin. Adapalene has an anti-inflammatory effect and thus reduces irritation and soreness. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that cause acne.
Storage
Drug Warnings
If you are known to be allergic to Pernex-Plus Gel or any other medicines, please tell your doctor. Do not apply Pernex-Plus Gel on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Pernex-Plus Gel is only for external use. Do not swallow Pernex-Plus Gel. In case of accidental swallowing, please consult a doctor. Avoid contact of Pernex-Plus Gel with nose, ears, mouth, or eyes. In case Pernex-Plus Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Avoid exposure to tanning beds or sunlight while using Pernex-Plus Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Pernex-Plus Gel. Do not apply Pernex-Plus Gel in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as irritation, scaling, or redness of the skin. If you have eczema (itchy, swollen, rough, and cracked skin) or sunburned skin, please inform your doctor before taking Pernex-Plus Gel.
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Pernex-Plus Gel contains Adapalene and Benzoyl peroxide. Adapalene is a retinoid (man-made vitamin A) that loosens the cells on the skin’s surface and unblocks pores by reducing the production of oil in the skin. Thereby, decreases pimples, spots, whiteheads and blackheads. Benzoyl peroxide is a keratolytic agent that works by breaking down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that causes acne.
Pernex-Plus Gel may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.
No, Pernex-Plus Gel is not recommended for eczema (itchy, cracked, swollen or rough skin) patients as it may cause severe irritation. Therefore, if you are suffering from eczema, inform your doctor before using Pernex-Plus Gel.
Yes, Pernex-Plus Gel may cause skin irritation as a side effect. However, if the irritation persists or worsens, stop using Pernex-Plus Gel and consult a doctor.
Yes, Pernex-Plus Gel may bleach coloured fabrics or hair. Therefore, avoid contact of Pernex-Plus Gel with hair or fabrics and thoroughly wash your hands after using Pernex-Plus Gel.
Yes, Pernex-Plus Gel may cause dryness of the skin. You can use a moisturizer while using Pernex-Plus Gel to prevent dry skin. However, do not apply Pernex-Plus Gel and moisturizer at the same time as it may reduce the effectiveness of Pernex-Plus Gel. Please consult a doctor before using other products with Pernex-Plus Gel.
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Special Advise
Disease/Condition Glossary
Acne (pimples): It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. Acne symptoms include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.

Have a query?
Alcohol
Safe if prescribed
Interaction of Pernex-Plus Gel with alcohol is unknown. Please consult a doctor before consuming alcohol while using Pernex-Plus Gel.
Pregnancy
Consult your doctor
Pernex-Plus Gel is a category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant.
Breast Feeding
Consult your doctor
It is unknown whether Pernex-Plus Gel is excreted in human milk. Therefore, Pernex-Plus Gel is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. However, do not apply Pernex-Plus Gel on the chest area to avoid the contact of Pernex-Plus Gel with the baby.
Driving
Safe if prescribed
Pernex-Plus Gel usually does not affect your ability to drive or operate machinery.
Liver
Consult your doctor
If you have any concerns regarding the use of Pernex-Plus Gel in patients with Liver problems, please consult a doctor.
Kidney
Consult your doctor
If you have any concerns regarding the use of Pernex-Plus Gel in patients with kidney problems, please consult a doctor.
Children
Safe if prescribed
Pernex-Plus Gel is not recommended for children below 9 years as the safety and effectiveness were not established.