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  3. Petaxel 260 mg Injection 43.4 ml

Petaxel 260 mg Injection 43.4 ml, Pack of 1 INJECTION
Petaxel 260 mg Injection 43.4 ml, Pack of 1 INJECTION
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Composition :

PACLITAXEL-260MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Petaxel 260 mg Injection 43.4 ml

Petaxel 260 mg Injection 43.4 ml belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. 
 
Petaxel 260 mg Injection 43.4 ml contains ‘Paclitaxel’, which works by stopping cell division and preventing the growth of certain cancer cells. 
 
In some cases, Petaxel 260 mg Injection 43.4 ml may cause common side effects, such as nausea, vomiting, mild diarrhoea, and joint or muscle pain. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Consult your doctor if you are pregnant, breastfeeding, think you may be pregnant or are planning pregnancy. Petaxel 260 mg Injection 43.4 ml is not recommended for children below 18 years. Inform your doctor about your health condition and medications to rule out any side effects.

Uses of Petaxel 260 mg Injection 43.4 ml

Ovarian cancer, breast cancer, non-small cell lung cancer.

Directions for Use

Petaxel 260 mg Injection 43.4 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Petaxel 260 mg Injection 43.4 ml belongs to the group of anti-cancer medicines called anti-microtubule agents used to treat various types of cancers, including ovarian and breast cancer (in advanced/spreading state or after surgery) and advanced-stage non-small cell lung cancer. It may also be used when other treatments have failed or in combination with other treatments. Petaxel 260 mg Injection 43.4 ml may also be indicated in patients with Kaposi’s sarcoma (cancer that develops from the cells that line lymph or blood vessels) associated with AIDS (Acquired Immuno-Deficiency Syndrome), where other treatments have not been effective. Petaxel 260 mg Injection 43.4 ml contains ‘Paclitaxel’, which works by preventing the growth of certain cancer cells. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Petaxel 260 mg Injection 43.4 ml
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Do not take Petaxel 260 mg Injection 43.4 ml if you are allergic to any of its components, if your white blood cell or platelet count is very low, if you have a serious uncontrolled infection, and Petaxel 260 mg Injection 43.4 ml has to be given for the treatment of Kaposi’s sarcoma (cancer that causes lesions in soft tissues), or if you have severe liver problems. Inform your doctor if you have heart disease, abnormal blood cell counts, irregular heartbeat, tingling, numbness, or burning sensation in fingers or toes, visual problems, if you are on radiation therapy, or if you have Kaposi’s sarcoma and have a sore or inflamed mouth. Also, inform your doctor if you are pregnant, breastfeeding, think you are pregnant or planning pregnancy.

Drug-Drug Interactions

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PaclitaxelRitonavir
Severe
PaclitaxelThalidomide
Severe

Drug-Drug Interactions

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PaclitaxelRitonavir
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
Taking Ritonavir and Petaxel 260 mg Injection 43.4 ml may significantly increase the blood levels of Petaxel 260 mg Injection 43.4 ml.

How to manage the interaction:
Taking Ritonavir with Petaxel 260 mg Injection 43.4 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. In case of any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelThalidomide
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
Taking thalidomide together with Petaxel 260 mg Injection 43.4 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Petaxel 260 mg Injection 43.4 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
PaclitaxelEtanercept
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
When Etanercept is used with Petaxel 260 mg Injection 43.4 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Petaxel 260 mg Injection 43.4 ml, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
PaclitaxelInfliximab
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
Combining Infliximab with Petaxel 260 mg Injection 43.4 ml can enhance the breakdown of Petaxel 260 mg Injection 43.4 ml in the body. This can reduce the treatment outcomes and can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Petaxel 260 mg Injection 43.4 ml with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PaclitaxelBaricitinib
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
Coadministration of baricitinib and Petaxel 260 mg Injection 43.4 ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Petaxel 260 mg Injection 43.4 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
PaclitaxelClozapine
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
Combining Petaxel 260 mg Injection 43.4 ml with Clozapine can increase the risk of infection.

How to manage the interaction:
Taking Petaxel 260 mg Injection 43.4 ml with Clozapine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
PaclitaxelCladribine
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
Combining Cladribine with Petaxel 260 mg Injection 43.4 ml can increase the risk of developing serious infections.

How to manage the interaction:
Taking Petaxel 260 mg Injection 43.4 ml with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PaclitaxelTofacitinib
Severe
How does the drug interact with Petaxel 260 mg Injection 43.4 ml:
Taking Tofacitinib with Petaxel 260 mg Injection 43.4 ml may increase the risk of infection.

How to manage the interaction:
Although taking Petaxel 260 mg Injection 43.4 ml and Tofacitinib together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Petaxel 260 mg Injection 43.4 ml Substitute

Substitutes safety advice

  • Gros-260 Injection 43.4 ml

    by Others

    ₹227.81per tablet

  • Chemotax * 260Mg/43.4Ml Inj

    by AYUR

    ₹179.83per tablet

  • Celtax 260mg/43.3ml Injection 1's

    by Others

    ₹9741.60per tablet

  • Caitxel 260 mg Injection 43.4 ml

    by Others

    ₹238.37per tablet

  • ALTAXEL 260MG INJECTION 43.4ML

    by Others

    ₹199.41per tablet

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:16 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Petaxel 260 mg Injection 43.4 ml works by stopping cell division and preventing the growth of certain cancer cells.

Petaxel 260 mg Injection 43.4 ml might cause sterility which could be permanent. Please talk to your doctor if you have any concerns.

The most common side effect of Petaxel 260 mg Injection 43.4 ml is hair loss. The hair may grow back after the treatment with Petaxel 260 mg Injection 43.4 ml is finished. However, consult your doctor if you have any concerns.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • FLUOXETINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • GEMFIBROZIL
  • CIMETIDINE
  • RITONAVIR
  • SAQUINAVIR
  • INDINAVIR
  • NELFINAVIR
  • EFAVIRENZ
  • NEVIRAPINE
  • CLOPIDOGREL

Special Advise

  • Your doctor may advise regular blood tests to check for liver activity, kidney function and blood cell count.
  • You and/or your partner should use reliable contraception during treatment with Petaxel 260 mg Injection 43.4 ml and for at least six months after the treatment.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in the breast when the breast cells begin to grow abnormally. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.

Ovarian Cancer: Ovarian cancer occurs when abnormal cells grow and multiply in the ovaries and fallopian tubes. Signs and symptoms include pain, swelling, or a feeling of pressure in the pelvis or abdomen, frequent or sudden urge to urinate, feeling full or trouble eating, a lump in the pelvic area, gas, bloating, or constipation.

Non-small cell lung cancer: It is a disease in which cancer cells form in the tissues of the lungs. Smoking is the major risk factor for non-small cell lung cancer. Symptoms include a cough that does not go away and shortness of breath.

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